Results 101 to 110 of about 21,579 (291)
Phytotherapy Research, EarlyView.Leonurine inhibits PKM2 to remodel hepatocyte glycolysis, thereby alleviating liver injury in alcoholic hepatitis. ABSTRACT Alcoholic hepatitis (AH) is a liver disease caused by long‐term heavy drinking. In the early stages, it usually manifests as fatty liver, which can then develop into liver fibrosis and cirrhosis.
Xuan‐Xuan Zhang +7 more
wiley +1 more source
Реальная клиническая практика: данные и доказательстваRelevance. Anticoagulants are commonly used during pregnancy is a fairly common practice. Due to the widespread use of oral anticoagulants in real practice and the high frequency of unplanned pregnancy, physicians should assess the risks and plan ...
Kh. A. Zagorodnikova +2 more
doaj +1 more source
Current Views on the Use of Valproic Acid in Women
Archives of Epilepsy, 2019 Valproic acid (VPA) is one of the most frequently prescribed antiepileptic drugs for idiopathic generalized epilepsy, chronic or migraine headache, and bipolar disorder; however concerns about teratogenic effects have resulted in limited usage of the ...
Kezban ASLAN KARA, Hacer BOZDEMİR
doaj +1 more source
Comparative teratogenicity of Chlorpyrifos and Malathion on Xenopus laevis development
, 2004 The embryotoxic potential of chlorpyrifos (CPF) and malathion (MTN), two organ ophosphorus insecticides (OPs), was evaluated by modified Frog Embryo Teratogenesis Assay-Xenopus (FETAX).
P. Bonfanti +9 more
core +1 more source
Rheumatology &Autoimmunity, EarlyView.A proposed mechanistic framework of systemic lupus erythematosus (SLE) and autoimmune thyroid disease (AITD) pathogenesis. In Stage 1, genetically susceptible individuals harbor risk variants within major histocompatibility complex (HLA) and non‐HLA loci that impair central and peripheral immune tolerance mechanisms within the thymic and peripheral ...
Elisa Elisa +3 more
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Urban walking routes are promoted as health‐supportive environments, yet they may also act as microenvironments of pollutant exposure during physical activity. This study evaluated heavy metal exposure along urban walking routes by integrating road dust metal concentrations, conventional health risk assessment, deposited inhalation dose, and ...
Berfin Sever +2 more
wiley +1 more source
Scientific opinion on the tolerable upper intake level for preformed vitamin A and β‐carotene
EFSA JournalFollowing two requests from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on the revision of the tolerable upper intake level (UL) for preformed vitamin A and β ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) +21 more
doaj +1 more source
Toxicological evaluation of porcine bile powder in Kunming mice and Sprague–Dawley rats
Frontiers in PharmacologyBackground: Porcine bile powder (PBP) is a traditional Chinese medicine that has been used for centuries in various therapeutic applications. However, PBP has not previously undergone comprehensive component analysis and not been evaluated for safety ...
Lirong Wu +14 more
doaj +1 more source
Regulating teratogenicity as a health risk
The development of scientific knowledge and regulatory policy with respect to teratogenicity is reviewed. The current debate on the definition of teratogenicity and on perceived risks, as illustrated by the Dutch Health Council report on teratogenicity ...
Gilden, Nanda, Bodewitz, Henk
core
The Future of the Teratogenicity Testing
The purpose of this review is to examine the importance, possible advantages and disadvantages of teratogenicity tests, and their future. For this purpose, numerous sources have been scanned in the field of teratogenicity. Although there are many methods
Aydin, Muhsin +2 more
core +1 more source