High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models. [PDF]
, 2016 Liver metastasis is the main cause of colon cancer-related death and is a recalcitrant disease. We report here the efficacy and safety of intra-portal-vein (iPV) targeting of Salmonella typhimurium A1-R on colon cancer liver metastasis in a nude-mouse ...
Bouvet, Michael +11 more
core +3 more sources
Prenatal Diagnosis, EarlyView.ABSTRACT Objective To present and evaluate the dynamic tongue contraction technique as a novel prenatal sonographic method for detecting soft palate clefts in fetuses with a cleft lip and palate (CLP) sequence. Methods This prospective cross‐sectional study was conducted at a tertiary care center between September 2023 and September 2024. Seven fetuses
Ettie Piura +6 more
wiley +1 more source
TERATOGENIC PROPERTIES OF DRUGS. BACKGROUND INFORMATION
Педиатрическая фармакология, 2013 The article presents the most significant steps in the development of ideas about drugs’ effects on fetus. It features the thalidomide tragedy and features of thalidomide teratogenic properties, as well as data on thalidomide syndrome prevention ...
A. A. Ivanova +2 more
doaj +1 more source
Fluorescence-guided surgery of a highly-metastatic variant of human triple-negative breast cancer targeted with a cancer-specific GFP adenovirus prevents recurrence. [PDF]
, 2016 We have previously developed a genetically-engineered GFP-expressing telomerase-dependent adenovirus, OBP-401, which can selectively illuminate cancer cells.
Bouvet, Michael +9 more
core +2 more sources
PLANTS, PEOPLE, PLANET, EarlyView.Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana +4 more
wiley +1 more source
The Control of Reproductive Hazards in the Workplace: A Prescription for Prevention [PDF]
, 1983 As workers become more aware that occupational exposure to toxic substances can impair their ability to bring healthy children into the world. they will begin to focus on legal mechanisms for reducing reproductive hazards in the workplace.
Ashford, Nicholas A. +1 more
core
A patient-derived orthotopic xenograft (PDOX) mouse model of a cisplatinum-resistant osteosarcoma lung metastasis that was sensitive to temozolomide and trabectedin: implications for precision oncology. [PDF]
, 2017 In the present study, we evaluated the efficacy of trabectedin (TRAB) and temozolomide (TEM) compared to cisplatinum (CDDP) on a patient-derived orthotopic xenogrraft (PDOX) of a lung-metastasis from an osteosarcoma of a patient who failed CDDP therapy ...
Dry, Sarah M +15 more
core +1 more source
Major effects on teratogen-induced facial clefting in mice determined by a single genetic region. [PDF]
, 1990 Jill Karolyi +3 more
openalex +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve +6 more
wiley +1 more source
Review on the Toxicity and Safety of Medicinal Plants during Pregnancy
ProceedingsIntroduction: Although herbs are widely used and considered safe, they can be toxic, especially during pregnancy [...]
Aniket Rajesing Girase +4 more
doaj +1 more source