Results 51 to 60 of about 12,518 (290)
Advanced Healthcare Materials, EarlyView.This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre +3 more
wiley +1 more source
The role of the pediatrican in the effort to prevent congenital malformations [PDF]
, 2011 N
Brent, Robert L, Dr.
core +1 more source
Advanced Photonics Research, EarlyView.Recent advances in nanophotonics‐based chiral biosensing approaches are comprehensively reviewed, highlighting key trends, advantages, and limitations of each technology. Special attention is given to emerging strategies that exploit magneto‐optical and quantum plasmonic phenomena to enhance sensitivity down to the level of a few molecules, or even a ...
Jorge Ricardo Mejía‐Salazar
wiley +1 more source
Embryonic stem cells: An alternative approach to developmental toxicity testing
Journal of Pharmacy and Bioallied Sciences, 2012 Stem cells in the body have a unique ability to renew themselves and give rise to more specialized cell types having functional commitments. Under specified growth conditions, these cell types remain unspecialized but can be triggered to become specific ...
S Tandon, S Jyoti
doaj +1 more source
Teratogenicity and Teratogenic Factors
MOJ Anatomy & Physiology, 2017 Teratology is the science that investigates the congenital malformations and their causes Intrauterine exposure to a toxicant particularly in early pregnancy induces embryonic and fetal changes ranging from none up to malformations and stillbirths The teratogenic agents include some viral spirochetal and protozoal infections physical agents as ionizing
openaire +1 more source
, 2014 Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust +15 more
core +2 more sources
Advanced Intelligent Discovery, EarlyView.This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng +4 more
wiley +1 more source
DNA Modifications: Function and Applications in Normal and Disease States
Biology, 2014 Epigenetics refers to a variety of processes that have heritable effects on gene expression programs without changes in DNA sequence. Key players in epigenetic control are chemical modifications to DNA, histone, and non-histone chromosomal proteins ...
Vichithra R. B. Liyanage +5 more
doaj +1 more source
Ethnic Identity and Teratogenic Risk Perceptions [PDF]
, 2016 Elevated perceptions of teratogenic risk can cause anxiety and confusion among pregnant women. To assess whether ethnic identity and demographic factors can influence teratogenic risk perceptions, 194 pregnant women in Houston were surveyed using the ...
Chan, Katie M
core +1 more source
The disintegrin echistatin in combination with doxorubicin targets high-metastatic human osteosarcoma overexpressing ανβ3 integrin in chick embryo and nude mouse models. [PDF]
, 2016 Echistatin, a cyclic RGD peptide, which is an antagonist of αvβ3 integrin (disintegrin), inhibited human osteosarcoma in the chick chorioallontoic membrane (CAM) model and tumor growth and pulmonary metastases in a nude mouse orthotopic model.
Bouvet, Michael +6 more
core +4 more sources