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Human teratogens: update 2010.
Birth defects research. Clinical and molecular teratology, 2011 A wide variety of human teratogens have been identified. The characteristics of human teratogens can be used in the assessment of apparent "new" teratogens, when postulated.
L. Holmes
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar +4 more
wiley +1 more source
Teratogenicity and hyperprolactinemia
Indian Journal of Psychiatry, 2009 Byline: Chittaranjan. Andrade CME Questions A) Drugs should be prescribed with caution to women of childbearing age because of the risk of teratogenicity, should conception occur during treatment; this concern is particularly important when prescribing drugs that will be required for long periods, such as in the maintenance therapy of epilepsy, bipolar
openaire +3 more sources
Ethnic Identity and Teratogenic Risk Perceptions [PDF]
, 2016 Elevated perceptions of teratogenic risk can cause anxiety and confusion among pregnant women. To assess whether ethnic identity and demographic factors can influence teratogenic risk perceptions, 194 pregnant women in Houston were surveyed using the ...
Chan, Katie M
core +1 more source
A method for human teratogen detection by geometrically confined cell differentiation and migration [PDF]
, 2014 Unintended exposure to teratogenic compounds can lead to various birth defects; however current animal-based testing is limited by time, cost and high inter-species variability.
Toh, Yi-Chin +3 more
core +2 more sources
Advanced Science, EarlyView.The dynamic “spring‐like” behavior of Pd─Cu dual atoms with PdN3─CuN3 coordination structure can be stretched and recovered with potential variation, which remarkably elevates the structural stability and catalytic activity of Cu atoms for electrocatalytic reduction reactions in strong‐acid electrolytes. The modulated electron‐orbit coupling effect and
Pei‐Hua Li +12 more
wiley +1 more source
Identifying signals of potentially harmful medications in pregnancy: use of the double false discovery rate method to adjust for multiple testing. [PDF]
, 2018 AIMS: Surveillance of medication use in pregnancy is essential to identify associations between first trimester medications and congenital anomalies (CAs). Medications in the same Anatomical Therapeutic Chemical classes may have similar effects. We aimed
Cavadino, A +2 more
core +2 more sources
A Splice‐Region Variant Causes an Atypical Presentation of GNAS Inactivation Disorder
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Pathogenic variants in GNAS can cause a wide range of diseases including pseudohypoparathyroidism, pseudopseudohypoparathyroidism, McCune‐Albright syndrome, among others. The specific phenotypic features that may be seen are influenced by the variant type and location in the gene, whether it causes loss or gain of function, and whether it is ...
Brandon S. Stone +11 more
wiley +1 more source
Biomedicines, 2022 Neural tube defects (NTDs) are the second most common congenital malformations of humans, characterized by impaired development of the central nervous system.
Jasmina Isaković +4 more
doaj +1 more source
Trends and predictors of women's risk perception about medications that may cause birth defects [PDF]
, 2019 The purpose of this study was to evaluate the proportion of women who reported perception of medications as a risk for birth defects, whether perceptions have changed over time, and identify socioeconomic and medical factors that are independent ...
Samuelson, Mark
core