Results 41 to 50 of about 7,092 (271)

MHC-associated immunopotentiation affects the embryo response to teratogens

open access: yes, 1994
SUMMARY The present study was performed to evaluate whether the effect of environmental teratogens can be modified by maternal immunostimulation.
HJA Carp, A Torchinsky, V Toder, A Fein
core   +1 more source

A Rare Form of Microcephalic Primordial Dwarfism due to NSMCE2 Deficiency (Seckel Syndrome Type 10): A Report of Macular Involvement

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic variants in NSMCE2 (MMS21), which encodes the SUMO E3 ligase subunit of the SMC5/6 chromatin‐maintenance complex, have recently been implicated in microcephalic primordial dwarfism (MPD), corresponding to Seckel syndrome type 10 (OMIM #617246).
Cristina Peduto   +5 more
wiley   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

open access: yesAnimal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang   +6 more
wiley   +1 more source

The effects of teratogens on prenatal human development

open access: yes, 2021
Teratologija je znanost koja se bavi uzrocima, razvojem, opisivanjem i klasifikacijom urođenih malformacija. Nakon talidomidske katastrofe 60-ih godina 20. stoljeća došlo je do naglog porasta u zanimanju za ovo područje.
Žulj, Iva
core  

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló   +5 more
wiley   +1 more source

Teratogenese por Drogas. [PDF]

open access: yes, 1977
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Tocoginecologia, Curso de Medicina, Florianópolis ...
Santos, Hilton Porto
core  

Prescribing Drugs to Pregnant Women in Primary Healthcare

open access: yesGenel Tıp Dergisi
It is crucial for the health of both the mother and the fetus that drugs are only used during pregnancy when absolutely necessary. While appropriate drugs can be used for appropriate indications during pregnancy, it is preferably recommended not to use ...
İzzet Fidancı
doaj   +1 more source

When meta‐analyses mislead: Promises and pitfalls in teratology counselling

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Meta‐analysis has become a central tool for evidence synthesis in clinical teratology, offering the promise of increased statistical power, earlier signal detection and consolidated guidance for teratology counselling. When conducted rigorously and interpreted carefully, pooled analyses can provide clinicians with a structured basis for risk ...
Yusuf Cem Kaplan, Nusret Uysal
wiley   +1 more source

A Review of the Teratogenic Factors Effect on Embryo

open access: yesJournal of Fasa University of Medical Sciences, 2017
Background & Objectives: Teratology is a branch of embryology science that studies causes, mechanisms and abnormal pattern development. Embryo growth traumatic factors during pregnancy are called teratogens that some teratogens pass the placental barrier
Manzarbanoo Shojaei fard   +2 more
doaj  

Overview of Neural Tube Defects: Gene–Environment Interactions, Preventative Approaches and Future Perspectives

open access: yesBiomedicines, 2022
Neural tube defects (NTDs) are the second most common congenital malformations of humans, characterized by impaired development of the central nervous system.
Jasmina Isaković   +4 more
doaj   +1 more source

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