Results 21 to 30 of about 11,254 (283)

Hormonal Contraceptives: What if Exposed During Pregnancy?

open access: yesErciyes Medical Journal, 2019
Objective: Hormonal contraceptives are contraindicated in pregnancy. However, some women may become pregnant while using contraceptives to prevent pregnancy.
Duygun Altıntaş Aykan, Yusuf Ergün
doaj   +1 more source

Evaluation of Teratogenic Activity of Antiepileptic Drug Lamotrigine in Mouse Fetuses

open access: yesFolia Medica, 2019
Background: Use of antiepileptic drugs during pregnancy can be associated with an increased risk of teratogenicity as well as congenital abnormalities. However, there are numerous discrepancies to determine whether lamotrigine, as an antiepileptic drug ...
Mobini Gholam Reza   +3 more
doaj   +1 more source

Risk factors and demographics for microtia in South America: a case-control analysis [PDF]

open access: yes, 2013
BACKGROUND: The etiopathogenesis of microtia is still unknown in the majority of the cases, particularly for individuals presenting with isolated microtia.
Castilla, Eduardo Enrique   +4 more
core   +1 more source

Teratogenicity with Olanzapine

open access: yesIndian Journal of Psychological Medicine, 2014
Olanzapine, a 2(nd) generation antipsychotic, is in use in the clinical practice for nearly a decade and a half now. It is classified as a category C drug with very few reports of its toxic effects on the fetus. In general, the risk benefit analysis warrants its use in pregnancy.
Sathya Prakash, Rakesh Kumar Chadda
openaire   +4 more sources

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

open access: yesAngewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

A Review of the Teratogenic Factors Effect on Embryo [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2016
Background & Objectives: Teratology is a branch of embryology science that studies causes, mechanisms and abnormal pattern development. Embryo growth traumatic factors during pregnancy are called teratogens that some teratogens pass the placental barrier
Manzarbanoo Shojaei fard   +2 more
doaj  

Medication use in pregnancy: a cross-sectional, multinational web-based study [PDF]

open access: yes, 2014
Objectives: Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. his study aimed to examine patterns and factors associated with medications use in pregnancy from a
Bjornsdottir, I.   +17 more
core   +5 more sources

Comparative Genomics Identifies Putative Interspecies Mechanisms Underlying Crbn-Sall4-Linked Thalidomide Embryopathy

open access: yesFrontiers in Genetics, 2021
The identification of thalidomide–Cereblon-induced SALL4 degradation has brought new understanding for thalidomide embryopathy (TE) differences across species. Some questions, however, regarding species variability, still remain.
Thayne Woycinck Kowalski   +29 more
doaj   +1 more source

Risk factors of congenital heart diseases: A hospital-based case-control study in Isfahan, Iran [PDF]

open access: yesARYA Atherosclerosis, 2020
BACKGROUND: Improving knowledge towards risk factors for congenital heart disease (CHD) is important because of its high mortality and morbidity and trying for prevention of occurrence of CHD.METHODS: This case-control study was conducted on a total of ...
Alireza Ahmadi   +3 more
doaj   +1 more source

Drug use during pregnancy

open access: yesHorizonte Médico, 2018
Due to ethical reasons, very scarce clinical assays have been conducted and published. This situation has resulted in the exaggeration of drug risk during pregnancy, thus limiting its reasonable use for chronic diseases in pregnant women.
José Sandoval Paredes   +1 more
doaj   +1 more source

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