Results 31 to 40 of about 11,254 (283)

A Religious Approach to the Role of Mothers in the function of Teratogens [PDF]

open access: yesزن در فرهنگ و هنر, 2013
The role of the motherhood is the most important factor in individual and social life of the human beings. Mother willingly and /or, unwillingly, plays her role in the destination of child via various factors.
Fahimeh Farahmandpour, Reza Firouzi
doaj   +1 more source

High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation

open access: yesCells, 2022
Human-relevant tests to predict developmental toxicity are urgently needed. A currently intensively studied approach makes use of differentiating human stem cells to measure chemically-induced deviations of the normal developmental program, as in a ...
Florian Seidel   +18 more
doaj   +1 more source

A method for human teratogen detection by geometrically confined cell differentiation and migration [PDF]

open access: yes, 2014
Unintended exposure to teratogenic compounds can lead to various birth defects; however current animal-based testing is limited by time, cost and high inter-species variability.
Toh, Yi-Chin   +3 more
core   +2 more sources

Ethnic Identity and Teratogenic Risk Perceptions [PDF]

open access: yes, 2016
Elevated perceptions of teratogenic risk can cause anxiety and confusion among pregnant women. To assess whether ethnic identity and demographic factors can influence teratogenic risk perceptions, 194 pregnant women in Houston were surveyed using the ...
Chan, Katie M
core   +1 more source

Real‐world trends in prenatal antirheumatic drug utilization in Ontario, Canada: A cross‐sectional time‐series analysis

open access: yesArthritis Care &Research, Accepted Article.
Objectives This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah   +6 more
wiley   +1 more source

Teratogens: a public health issue – a Brazilian overview

open access: yesGenetics and Molecular Biology, 2017
Congenital anomalies are already the second cause of infant mortality in Brazil, as in many other middle-income countries in Latin America. Birth defects are a result of both genetic and environmental factors, but a multifactorial etiology has been more ...
Thiago Mazzu-Nascimento   +6 more
doaj   +1 more source

Trends and predictors of women's risk perception about medications that may cause birth defects [PDF]

open access: yes, 2019
The purpose of this study was to evaluate the proportion of women who reported perception of medications as a risk for birth defects, whether perceptions have changed over time, and identify socioeconomic and medical factors that are independent ...
Samuelson, Mark
core  

Identifying signals of potentially harmful medications in pregnancy: use of the double false discovery rate method to adjust for multiple testing. [PDF]

open access: yes, 2018
AIMS: Surveillance of medication use in pregnancy is essential to identify associations between first trimester medications and congenital anomalies (CAs). Medications in the same Anatomical Therapeutic Chemical classes may have similar effects. We aimed
Cavadino, A   +2 more
core   +2 more sources

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng   +4 more
wiley   +1 more source

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