Results 51 to 60 of about 6,483 (296)

Overview of Neural Tube Defects: Gene–Environment Interactions, Preventative Approaches and Future Perspectives

Biomedicines, 2022
Neural tube defects (NTDs) are the second most common congenital malformations of humans, characterized by impaired development of the central nervous system.
Jasmina Isaković, Iva Šimunić, Denis Jagečić, Valentina Hribljan, Dinko Mitrečić   +4 more
doaj   +1 more source

Teratogenese por Drogas. [PDF]

, 1977
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Tocoginecologia, Curso de Medicina, Florianópolis ...
Santos, Hilton Porto
core  

Termination of Pregnancy Following Periconception Isotretinoin Exposure in South Korea

Clinical and Experimental Obstetrics & Gynecology
Background: Despite South Korea’s Ministry of Food and Drug Safety (MFDS) risk management program (RMP) since June 2019, isotretinoin prescriptions have surged 2.5 times from 0.39 million in 2017 to 0.97 million in 2021.
Young-Rae Lee, Dong-Won Hwang, Kyoung-Chul Chun, Young-Ah Kim, Jae-Whoan Koh, Jung-Yeol Han, June-Seek Choi, Hye-Young Kwon   +7 more
doaj   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

A Review of the Teratogenic Factors Effect on Embryo

Journal of Fasa University of Medical Sciences, 2017
Background & Objectives: Teratology is a branch of embryology science that studies causes, mechanisms and abnormal pattern development. Embryo growth traumatic factors during pregnancy are called teratogens that some teratogens pass the placental barrier
Manzarbanoo Shojaei fard, Samira Malekzadeh, Mehrdad Shariati   +2 more
doaj  

Use of antiemetics in early pregnancy 2012–2022: A cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
Aim Nausea and vomiting in pregnancy impact quality of life, yet many pregnant women feel dismissed by healthcare professionals, despite the safety of first‐line antiemetic treatments for both mother and fetus. Therefore, this study aims to describe the prevalence of patient‐reported antiemetic use in early pregnancy in Copenhagen, Denmark, the changes
Katrine Bak Wraae, Nanna Roed Ballegaard, Mie Lærkeholm Hede, Line Buchgreitz, Ane Lilleøre Rom, Hanne Kristine Hegaard, Nina Olsén Nathan   +6 more
wiley   +1 more source

Rheumatologists’ knowledge of contraception, teratogens, and pregnancy risks

, 2018
Introduction Rheumatologists are essential partners in planning and managing pregnancies in women with lupus. Whether they know the essentials of contraceptive and medical treatment in pregnancy, however, is unknown.
Gillian D Sanders, Jessica Revels, Lisa Criscione-Schreiber, Megan EB Clowse, Amanda M Eudy   +4 more
core   +1 more source

Identification of major congenital malformations based on healthcare databases in France: A proof‐of‐concept study using the epi‐meres nationwide mother–child register

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Besides registries, healthcare databases can provide useful information for assessing the frequency of major congenital malformations (MCMs) and investigating their risk factors, particularly medication exposures. This study aimed to assess the validity of MCMs identification based on French national, comprehensive healthcare databases ...
Tom Duchemin, Lise Marty, Jérôme Drouin, Sara Miranda, Jérémie Botton, Valérie Olié, Alain Weill, Rosemary Dray‐Spira   +7 more
wiley   +1 more source

Prenatal teratogens and the development of adult mental illness

, 1999
Our findings in the Helsinki Influenza Study and the Danish Forty Year Study lead us to conclude that a 2nd-trimester maternal influenza infection may increase risk for adult schizophrenia or adult major affective disorder.
SARNOFF A. MEDNICK, JENNIFER B. WATSON, MATTI HUTTUNEN, XUEYI WANG   +3 more
core   +1 more source

Drug use during pregnancy

Horizonte Médico, 2018
Due to ethical reasons, very scarce clinical assays have been conducted and published. This situation has resulted in the exaggeration of drug risk during pregnancy, thus limiting its reasonable use for chronic diseases in pregnant women.
José Sandoval Paredes, Cindy Sandoval Paz   +1 more
doaj   +1 more source