Results 11 to 20 of about 11,254 (283)

Pregnancy and neonatal outcomes after periconceptional exposure to isotretinoin in Koreans [PDF]

Obstetrics & Gynecology Science, 2022
Objective Isotretinoin should not be used during pregnancy because of the risk of birth defects. Most pregnant women exposed to isotretinoin choose voluntary pregnancy termination due to concerns about birth defects.
Eun-Hwan Cha, NaeRy Kim, Ho-Seok Kwak, Hae Ji Han, Sung Hong Joo, June-Seek Choi, Kyoung-Chul Chun, Young-Ah Kim, Jae-Whoan Koh, Jung Yeol Han   +9 more
doaj   +1 more source

Effects of sub-lethal teratogen exposure during larval development on egg laying and egg quality in adult Caenorhabditis elegans [version 1; referees: 2 approved]

F1000Research, 2016
Background: Acute high dose exposure to teratogenic chemicals alters the proper development of an embryo leading to infertility, impaired fecundity, and few viable offspring.
Alexis Killeen, Caralina Marin de Evsikova   +1 more
doaj   +1 more source

Functional Polymorphisms in the p53 Pathway Genes on the Genetic Susceptibility to Zika Virus Teratogenesis

Frontiers in Cellular and Infection Microbiology, 2021
Congenital Zika Syndrome (CZS) occurs in up to 42% of individuals exposed to ZIKV prenatally. Deregulation in gene expression and protein levels of components of the p53 signaling pathway, such as p53 and MDM2, due to ZIKV infection has been reported ...
Julia A. Gomes, Julia A. Gomes, Julia A. Gomes, Julia A. Gomes, Eduarda Sgarioni, Igor A. Vieira, Igor A. Vieira, Lucas R. Fraga, Lucas R. Fraga, Lucas R. Fraga, Lucas R. Fraga, Patrícia Ashton-Prolla, Patrícia Ashton-Prolla, Ana Cláudia P. Terças-Tretell, Juliana H. da Silva, Bethânia F.R. Ribeiro, Marcial F. Galera, Thalita M. de Oliveira, Maria Denise F. Carvalho de Andrade, Isabella F. Carvalho, Lavínia Schuler-Faccini, Lavínia Schuler-Faccini, Lavínia Schuler-Faccini, Fernanda S. L. Vianna, Fernanda S. L. Vianna, Fernanda S. L. Vianna, Fernanda S. L. Vianna   +26 more
doaj   +1 more source

Arterial dysgenesis and limb defects : Clinical and experimental examples [PDF]

, 2017
Acknowledgements This article is dedicated to Dr David S. Packard Jr. With thanks to Dr John DeSesso, Dr Lewis B. Holmes, Dr Mark Levinsohn, Dr David S.
Hootnick, David R., Vargesson, Neil
core   +1 more source

Knowledge regarding teratogens among women of childbearing age at a large tertiary care center in Saudi Arabia

Journal of Family Medicine and Primary Care, 2020
Aim: To investigate the knowledge of Saudi women regarding the teratogenic effects of environmental agents such as fever, some chronic conditions and medications and its association with certain socio-demographic factors.
Wejdan Alhamdan, Afaf Moukaddem, Nourh AlOtaibi, Adibah Aledrees, Nada Alhatem, Nada Alshehri, Samaher Alfaraj, Maysoon Aladham   +7 more
doaj   +1 more source

Teratogenic Effects of Diatom Metabolites on Sea Urchin Paracentrotus lividus Embryos

Marine Drugs, 2010
The diatom-derived polyunsaturated aldehydes (PUAs), 2-trans,4-trans-decadienal, 2-trans,4-trans-octadienal, 2-trans,4-trans,7-octatrienal, 2-trans,4-trans-heptadienal, as well as tridecanal were tested on early and later larval development in the sea ...
Giovanna Romano, Antonio Miralto, Adrianna Ianora   +2 more
doaj   +1 more source

Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models. [PDF]

, 2015
Malignant melanoma requires precise resection in order to avoid metastatic recurrence. We report here that the telomerase-dependent, green fluorescent protein (GFP)-containing adenovirus OBP-401 could label malignant melanoma with GFP in situ in ...
Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M, Kagawa, Shunsuke, Kishimoto, Hiroyuki, Takehara, Kiyoto, Urata, Yasuo, Yano, Shuya   +7 more
core   +1 more source

Expert consensus on neurodevelopmental outcomes in pregnancy pharmacovigilance studies

Frontiers in Pharmacology, 2023
Background: Exposure in utero to certain medications can disrupt processes of fetal development, including brain development, leading to a continuum of neurodevelopmental difficulties.
R. L. Bromley, R. L. Bromley, M. Bickle Graz, M. Bluett-Duncan, C. Chambers, P. Damkier, K. Dietrich, H. Dolk, K. Grant, S. Mattson, K. J. Meador, H. Nordeng, H. Nordeng, T. F. Oberlander, A. Ornoy, A. Revet, A. Revet, J. Richardson, J. Rovet, J. Rovet, L. Schuler-Faccini, E. Smearman, V. Simms, C. Vorhees, K. Wide, A. Wood, L. Yates, L. Yates, E. Ystrom, E. Ystrom, T. A. Supraja, J. Adams   +31 more
doaj   +1 more source

Use of psychotropic medications during pregnancy: perception of teratogenic risk among physicians in two Latin American countries

Brazilian Journal of Psychiatry, 2014
Objective: Pregnant women and their health care professionals commonly believe that use of medications during pregnancy may be harmful to the unborn fetus.
Amaury Cantilino, Laura Lorenzo, Juliane dos A. de Paula, Adrienne Einarson   +3 more
doaj   +1 more source

Teratogenic risk and contraceptive counselling in psychiatric practice: analysis of anticonvulsant therapy [PDF]

, 2013
<p>Background: Anticonvulsants have been used to manage psychiatric conditions for over 50 years. It is recognised that some, particularly valproate, carbamazepine and lamotrigine, are human teratogens, while others including topiramate require ...
A Basan, A Wieck, Andrea Perry, D Taylor, E Perrucs, EB Samrén, FJE Vajda, H Grunze, JL Heffner, Julie Langan, L Citrome, L James, Maria Oto, N Adab, O Diav-Citrin, PA Lambert, S Fried, S Leucht, S Matalon, Scotland's Population, T Okuma, T Tomson, VK Hiilesmaa, World Health Organisation   +23 more
core   +2 more sources