Results 141 to 150 of about 2,627 (175)

Teratozoospermia and asthenozoospermia are associated with specific epigenetic signatures

Andrology, 2016
Semen analysis is commonly used as a tool to assess the fertility potential of a male, despite its relatively low predictive power. In this study, we have assessed associations between semen analysis findings (low count, low motility, low viability, poor sperm penetration assay results, poor morphology, and increased DNA damage) and DNA methylation ...
T G, Jenkins, K I, Aston, J M, Hotaling, M B, Shamsi, L, Simon, D T, Carrell   +5 more
openaire   +2 more sources

A Cascade of epistatic interactions regulating teratozoospermia in mice

Mammalian Genome, 2015
Infertility in humans and subfertility in domestic animals are two major reproductive problems. Among human couples, ~15% are diagnosed as infertile, and males are considered responsible in about 50% of the cases. To examine male fertility, various sperm tests including analyses of sperm morphology, sperm count and sperm mobility are usually performed.
Keitaro, Hirawatari, Naoto, Hanzawa, Ikuo, Miura, Shigeharu, Wakana, Hideo, Gotoh   +4 more
openaire   +2 more sources

Expression of NOX5 in human teratozoospermia compared to normozoospermia

Andrologia, 2012
Spermatozoa are capable of producing small amounts of reactive oxygen species (ROS), and sperm in teratozoospermia generate more ROS than sperm in normozoospermia. The source of ROS production in ejaculated human sperm has not been fully clarified.
E, Ghani, S, Keshtgar, M, Habibagahi, A, Ghannadi, M, Kazeroni   +4 more
openaire   +2 more sources

Teratozoospermia and in-vitro fertilization: a randomized prospective study

Human Reproduction, 1994
A prospective randomized study was conducted to assess the prognostic value of sperm morphology in an in-vitro fertilization (IVF) programme, using strict criteria. The first group (T, teratozoospermic) included 32 couples with an isolated teratozoospermia in the male partner (morphology < 9% normal).
W, Ombelet, F L, Fourie, H, Vandeput, E, Bosmans, A, Cox, M, Janssen, T, Kruger   +6 more
openaire   +2 more sources

[Genetic aspects of the teratozoospermia].

Gynecologie, obstetrique & fertilite, 2009
Recent mutation identification in well-known sperm defects gives proof that there are genetic causes of infertility. Familial forms and some features of the spermograms lead toward the genetic origin of these syndromes. For each syndrome, several clinical aspects and partial forms were described.
M-R, Guichaoua, C, Geoffroy-Siraudin, G, Mercier, V, Achard, O, Paulmyer-Lacroix, C, Metzler-Guillemain   +5 more
openaire   +1 more source

[DAZL gene polymorphisms and astheno-teratozoospermia].

Zhonghua nan ke xue = National journal of andrology, 2013
To investigate the association between single nucleotide polymorphism (SNP) of the DZAL gene in infertile Han Chinese males with astheno-teratozoospermia.We collected semen samples from 173 infertile Han Chinese men with astheno-teratozoospermia (case group) and 175 age-matched normal male volunteers (control group) for semen routine and morphological ...
Lu-Wei, Ye, Qing-Feng, Yu, Xue-Xi, Yang, Jing-Ping, Li, Xiao-Qiang, Wu, Yong-Hai, Zhang, Xiang-Ming, Mao   +6 more
openaire   +2 more sources

O-176 Genetics of teratozoospermia

Human Reproduction
Abstract Male infertility, affecting over 20 million men worldwide, is a significant health concern with a strong yet underexplored genetic basis. Recent advances in genetic sequencing, particularly the use of whole-exome sequencing (WES), have enabled the identification of many genetic causes of teratozoospermia, including AURKC ...
openaire   +1 more source

[Molecular genetic mechanisms of teratozoospermia].

Zhonghua nan ke xue = National journal of andrology, 2014
Teratozoospermia is one of the important factors contributing to male infertility, and its pathogenesis is not yet clear. Recent years have witnessed some progress in the researches on sperm morphology, and some genes have been confirmed to be correlated with spermatogenesis.
Rui-Zhi, Liu, Jing, Wu, Rui-Xue, Wang
openaire   +1 more source

Oxidative stress and phenotype frequencies of paraoxonase‐1 in teratozoospermia

Andrologia, 2019
Oxidative stress causes infertility in men by affecting especially sperm morphology. The aim of the study was to examine the frequencies of paraoxonase-1 (PON1) phenotypes and the serum PON1, arylesterase, total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index, catalase and thiol levels in teratozoospermic infertile men and ...
Omer Faruk Ozer, Habib Akbulut, Eray Metin Guler, Hifa Gulru Caglar, Fatih Gevher, Fatmanur Koktasoglu, Sahabettin Selek   +6 more
openaire   +3 more sources

[Teratozoospermia affects in vitro fertilization outcome].

Zhonghua nan ke xue = National journal of andrology, 2009
To analyze the possible causes of total fertilization failure (TFF) in conventional in vitro fertilization (IVF).We included in this study 552 couples who accomplished the first conventional IVF cycle in our center from January 2007 to August 2008. All the males met the Kruger/Tygerberg criteria, with the teratozoospermia rate < 96% in the previous 12 ...
Juan-Zi, Shi, Xia, Xue, Zhou, Zhang, Han-Ying, Zhou, Bao-Zhu, Guo   +4 more
openaire   +1 more source