Results 21 to 30 of about 9,832 (188)

The Influence of Oral Terbinafine on Gut Fungal Microbiome Composition and Microbial Translocation in People Living with HIV Treated for Onychomycosis

Journal of Fungi, 2023
People living with HIV (PLWH) display altered gut epithelium that allows for the translocation of microbial products, contributing to systemic immune activation.
Jing Ouyang, Jiangyu Yan, Xin Zhou, Stéphane Isnard, Shengquan Tang, Cecilia T. Costiniuk, Yaling Chen, Jean-Pierre Routy, Yaokai Chen   +8 more
doaj   +1 more source

Trichophyton indotineae: Epidemiology, antifungal resistance and antifungal stewardship strategies. [PDF]

J Eur Acad Dermatol Venereol
There is a concerning trend of widespread and severe superficial fungal infections caused by a new pathogen—Trichophyton indotineae—resistant to standard antifungal therapies. T. indotineae is now spreading globally and evolving. There is increasing urgency for healthcare providers and policy makers to initiate surveillance systems and antifungal ...
Gupta AK, Susmita, Nguyen HC, Liddy A, Talukder M, Wang T, Magal L, Chowdhary A, Shemer A, Saunte DML, Hay R, Piguet V.   +11 more
europepmc   +2 more sources

Modulation of yeast Erg1 expression and terbinafine susceptibility by iron bioavailability

Microbial Biotechnology, 2022
Ergosterol is a specific sterol component of yeast and fungal membranes. Its biosynthesis is one of the most effective targets for antifungal treatments.
Tania Jordá, Ana Martínez‐Martín, María Teresa Martínez‐Pastor, Sergi Puig   +3 more
doaj   +1 more source

Investigation on utility of some novel terpenes on transungual delivery of terbinafine for the management of onychomycosis

Dermatology Practical & Conceptual, 2022
Introduction: Onychomycosis is a fungal disorder of the nail which afflicts 5% of the population worldwide. The disease is strenuous to cure as it is chronic, hard to eliminate and tends to recur. Topical therapy is at the forefront for the treatment of
Isha Gupta, Syeda Nashvia Adin, Mohd Aqil, Mohd Mujeeb, Yasmin Sultana   +4 more
doaj   +1 more source

Efficacy and safety of terbinafine 500 mg once daily in patients with dermatophytosis

Indian Journal of Dermatology, 2017
Introduction: Dermatophytosis are the most common fungal infections globally. Terbinafine is considered to have good potency against dermatophytes, but resistance to terbinafine is on the rise.
P Ravindra Babu, A J S Pravin, Gaurav Deshmukh, Dhiraj Dhoot, Aniket Samant, Bhavesh Kotak   +5 more
doaj   +1 more source

Fungal Translocation Marker in People Living with HIV Needing Treatment for Onychomycosis: A Protocol for the Prospective Pilot Study

​​​​​​​​Infectious Diseases & Immunity, 2022
. Increased microbial translocation and chronic immune activation are two critical problems for people living with HIV (PLWH) in the antiretroviral therapy (ART) era.
Yaling Chen, Jing Ouyang, Stéphane Isnard, Cecilia T. Costiniuk, Jiangyu Yan, Xin Zhou, Jean-Pierre Routy, Yaokai Chen, Wei Zhao   +8 more
doaj   +1 more source

TREATMENT OF DERMATOPHYTE ONYCHOMYCOSIS WITH TERBINAFINE (LAMISIL) PULSE THERAPY [PDF]

Journal of IMAB, 2004
Terbinafine is the most active currently available antidermatophyte agent with fungicidal action. The aim of the present study was to assess the efficacy of terbinafine pulse therapy in the treatment of dermatophyte nail infections.
Sonia Valkova
doaj   +1 more source

Synergistic effect of terbinafine and amphotericin B in killing Fonsecaea nubica in vitro and in vivo

Revista do Instituto de Medicina Tropical de São Paulo
Chromoblastomycosis is a chronic fungal infection. Itraconazole and terbinafine are the most recommended antifungal drugs for chromoblastomycosis, while amphotericin B is not usually recommended.
Jing Zhang, Xiaoyan Wu, Meirong Li, Jiamin Huang, Songchao Yin, Huaiqiu Huang, Chun Lu, Liyan Xi   +7 more
doaj   +1 more source

Terbinafine versus itraconazole: a long-term, randomized, double-blind, clinical trial in chronic pulmonary aspergillosis. A pilote study [PDF]

Journal of Health and Social Sciences, 2016
Background: The frequency of pulmonary aspergillosis has been increasing for decades. Standard oral treatment is associated with tolerability problems and interactions with commonly used medications.
Gianfranco Schiraldi, Salvatore Lo Cicero, Claudio Rossetti, Delia Colombo, Michele Chiericozzi, Elvana Kola, Luigi Allegra   +6 more
doaj   +1 more source

To compare the efficacy of oral terbinafine alone against the combination of oral terbinafine and intense pulsed light (IPL) in difficult to treat tinea patients

MGM Journal of Medical Sciences, 2021
Background: Dermatophytosis is a major health problem in developing countries, with their increase in resistance patterns toward various antifungals being the main reason for concern.
Suraj Pawar, Ashish R Deshmukh
doaj   +1 more source