Results 31 to 40 of about 9,832 (188)

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

One‐Pot Ruthenium‐Catalyzed Synthesis of Benzyl/Allyl‐Halide Substituted (dihydro)naphthalenes via Radical Benzannulation

ChemistryEurope, EarlyView.
A one‐pot protocol to synthesize reactive benzyl‐ and allyl‐halide‐substituted (dihydro)naphthalenes from 2,3‐aryl‐1,3‐butadiene substrates and halogenated alkanes has been developed, using [Cp*RuCl(PPh3)2] as the catalyst. Mechanistic studies revealed an atom transfer radical addition and radical benzannulation sequence, followed by HCl elimination ...
Nicole S. van Leeuwen, David Vesseur, Thijmen Bonhoff, Jeffrey van Laar, Coert E. J. van Lare, Simon Mathew, Sonja Pullen, Joost N. H. Reek, Aalbert Zwijnenburg, Bas de Bruin   +9 more
wiley   +1 more source

Emerging antifungal resistance in Trichophyton mentagrophytes: insights from susceptibility profiling and genetic mutation analysis

Emerging Microbes and Infections
Trichophyton species, the leading cause of dermatophytosis globally, are increasingly resistant to antifungal treatments, concerns about effective management strategies.
Yakun Shao, Jin Shao, Sybren de Hoog, Paul Verweij, Lin Bai, Riina Richardson, Malcolm Richardson, Zhe Wan, Ruoyu Li, Jin Yu, Yinggai Song   +10 more
doaj   +1 more source

Therapeutic effects of a novel DA5505 formulation on a guinea pig model of tinea pedis

Dermatologica Sinica, 2017
Background/Objective: Tinea pedis, a superficial mycosal infection affecting the soles and toe webs of feet, is generally treated with terbinafine. However, the main problem with available marketed formulations is their inability to deliver terbinafine ...
Raj Kumar Thapa, Ju Yeon Choi, Sang Duk Han, Ga Hyeon Lee, Chul Soon Yong, Joon-Ho Jun, Jong Oh Kim   +6 more
doaj   +1 more source

The Rare Presentation of Deep Dermatophytosis‐Trichophyton in an Immunosuppressed Patient

JEADV Clinical Practice, EarlyView.
ABSTRACT Dermatophytes typically cause superficial skin infections characterized by an active border. However, they can present atypically invading deeper in immunocompromised patients. We present a case of a 72‐year‐old woman with bullous pemphigoid who had received oral prednisolone for 3 months and developed umbilicated papules.
Jidapa Triwatcharikorn, Nitina Yeesibsean, Jirapon Jesrichai, Chanat Kumtornrut   +3 more
wiley   +1 more source

In vitro Evaluation of Antifungal Activity of Terbinafine Nano Form against Yeast Organism Isolated in Thumby Labs Ajman

Journal of Pure and Applied Microbiology
The goal of this study is to evaluate the antifungal activity of terbinafine in its nano form against yeast organisms in vitro and compare its effectiveness to the normal form of terbinafine.
Ahmed Luay Osman, Shery Jacob, Abdelrahman Mohammed, Rana Raid, Alaa Hammoud, Sofiyat Ajoke Zayyad, Zulekha Tora Shemote, Praveen Kumar, Devapriya Finney Shadroch   +8 more
doaj   +1 more source

Modified Screen-Printed Microchip for Potentiometric Detection of Terbinafine Drugs

Journal of Chemistry, 2022
The development of miniaturized microchips has widespread and growing interest in manufacturing potentiometric sensors with extremely valuable modifying response characteristics.
Menna El-Beshlawy, Hassan Arida
doaj   +1 more source

Towards an Early Clinical and Biological Resistance Detection in Dermatophytosis: About 2 Cases of Trichophyton indotineae

Journal of Fungi, 2023
Trichophyton indotineae causes resistant dermatophytosis to terbinafine. The global spread of terbinafine-resistant Trichophyton indotineae strains with mutations in the squalene epoxidase gene is a major issue.
Giuseppe Russo, Laurence Toutous Trellu, Lionel Fontao, Béatrice Ninet   +3 more
doaj   +1 more source

Successful Use of Bimekizumab in Refractory Acute Generalised Exanthematous Pustulosis Triggered by Amoxicillin‐Clavulanate

JEADV Clinical Practice, EarlyView.
ABSTRACT Acute generalised exanthematous pustulosis (AGEP) is a rare, acute neutrophilic dermatosis most commonly triggered by drugs, which typically resolves within 2 weeks following withdrawal of the causative agent. Topical and systemic corticosteroids remain the standard treatment.
Alexandra Junge, Charlotte Vogel, Theresa Hempel, Basil Signer, Nikhil Yawalkar, Kristine Heidemeyer   +5 more
wiley   +1 more source

Comparison of efficacy combination oral terbinafine pulse-dosed and topical 8% ciclopirox olamine with terbinafine monotherapy for onychomycosis: An evidence-based case report [PDF]

JDVI (Journal of General Procedural Dermatology & Venereology Indonesia), 2017
Background: Onychomycosis is a fungal infection of the nails, which manifested as nail discoloration, thickening, and detachment from the nail bed. It is not life-threatening, however inappropriate treatment of onychomycosis might lead to complications ...
Marsha Bianti, Sandra Widaty, Teffy Nuary   +2 more
doaj   +1 more source