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Steroid-Modified Dermatophytosis: A Clinical and Diagnostic Challenge. [PDF]
CureusJadhav V, Mane PM, Patil SR.
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Reliability of a terbinafine agar containing method for the screening of dermatophyte resistance
Medical Mycology, 2023 Abstract The increase in terbinafine resistance worldwide due to Trichophyton indotineae underlies the need for surveillance networks, deploying easy to perform methods to correctly identify resistant isolates and thereby reduce their spread.
Alicia Moreno Sabater +2 more
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Terbinafine and Itraconazole Resistance in Dermatophytes
2021Terbinafine-resistant dermatophytes in patients were exceptional before the second decade of this century. However, acquired resistance to commonly used antifungal compounds has recently emerged in several countries. Resistance towards terbinafine is generated by missense mutations in the squalene epoxidase enzyme targeted by the drug, while recorded ...
Michel Monod +2 more
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Terbinafine resistance in dermatophytes: Time to revisit alternate antifungal therapy
Journal De Mycologie Medicale, 2021Resistant superficial dermatophytic infections of the skin and its appendages have emerged as a major health problem in India. Mutations in Squalene epoxidase gene have led to increasing incidence of resistance to terbinafine in dermatophytic isolates.
S N Bhattacharya
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Terbinafine-Resistant Dermatophytes and the Presence of Trichophyton indotineae in North America
Journal of Clinical Microbiology, 2023Dermatophytes are common causes of skin, hair, and nail infections in humans. The most common species causing infections in humans are Trichophyton rubrum , Trichophyton mentagrophytes , and Trichophyton interdigitale .
Connie F. Cañete-Gibas +8 more
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Identification of genes involved in terbinafine resistance in Aspergillus nidulans
Letters in Applied Microbiology, 2002To determine the pattern and the genetic basis of resistance to terbinafine, a drug extensively used for the treatment of fungal infections in humans.Four resistant mutants from Aspergillus nidulans isolated after irradiation with ultraviolet light were crossed with the master strain F (MSF).
E M F, Rocha +2 more
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[Terbinafine-resistant dermatophytoses and onychomycosis due to Trichophyton rubrum].
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2021In recent years, therapy-refractory courses of dermatophytoses have increasingly become the focus of attention. The most frequent pathogens are Trichophyton (T.) rubrum and T. mentagrophytes. In addition to local therapy, first-line treatment includes terbinafine, an allylamine antifungal agent that acts by inhibiting squalene epoxidase and thus ...
L, Appelt +10 more
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Trichophyton indotineae and other terbinafine-resistant dermatophytes in North America
Journal of Clinical Microbiology, 2023ABSTRACT Dermatophyte infections (a.k.a. ringworm, tinea) affect an estimated 20%–25% of the world’s population. In North America, most dermatophytoses are caused by Trichophyton rubrum or Trichophyton mentagrophytes species complexes. Severe and antifungal-resistant dermatophytoses
Shawn R. Lockhart +2 more
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Assessment of Efficacy of Terbinafine in The Treatment of Resistant Dermatophytosis
North East Medical College JournalAbstract The term “dermatophytosis” refers to a group of pathogenic fungi called dermatophytes that have a strong affinity for the keratinized tissues found in nails, skin, and hair. There are already a number of antifungal medications available to treat mycoses, yet they have limited cellular targets, and fungus may develop tolerance or resistance to ...
Iqbal Ahmed +4 more
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