Results 51 to 60 of about 11,982,284 (288)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

High-order sliding mode control of a DC motor drive via a switched controlled multi-cellular converter [PDF]

, 2011
In this article, we present a high-order sliding mode controller of a DC motor drive connected to a multi-cellular converter. More specifically, we design a second-order (super-twisting) control algorithm for the speed regulation of a DC motor. For this,
Benmansour, Khelifa, Marouf, Alaa, K. Busawon, K. Benmansour, Djemaï, Mohamed, Busawon, Krishna, M. Djemaï, A. Marouf   +7 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Fin stabilizer control strategy based on adaptive sliding mode

Applied Ocean Research
Ships are typically equipped with fin stabilizers to effectively weaken ship’s roll and enhance the voyage's safety. To achieve better anti-roll performance, this study proposes an adaptive sliding mode control (SMC) method for a roll reduction ...
Ling Deng, Xiujun Xu, Yu Shao
doaj   +1 more source

Finite time tracking control of mobile robot based on non-singular fast terminal sliding mode

Systems Science & Control Engineering, 2018
To solve the tracking problem of mobile robot, a hybrid control algorithm based on back-stepping control and non-singular fast terminal sliding mode control is proposed in this paper. The algorithm not only ensures the pose tracking of the robot but also
Xinchen Guo, Zhenying Liang, Caihong Li
doaj   +1 more source

Adaptive Second Order Recursive Terminal Sliding Mode Control for a Four-Wheel Independent Steer-by-Wire System

IEEE Access, 2020
An adaptive second order recursive terminal sliding mode (SO-RTSM) is developed for the steering angle control of a four-wheel independent steer-by-wire (4WI-SbW) system.
Bin Deng, Ke Shao, Han Zhao
doaj   +1 more source

Second‐order adaptive integral terminal sliding mode approach to tracking control of robotic manipulators

IET Control Theory & Applications, 2021
A second‐order adaptive integral terminal sliding mode controller is proposed for the trajectory tracking control of robotic manipulators with uncertainties.
Shuang Hao, Lingyan Hu, Peter Xiaoping Liu   +2 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Barrier Function-Based Adaptive Super-Twisting Integral Terminal Sliding Mode Control for a Quad-Rotor UAV

IEEE Access
In this paper, a novel barrier function-based super-twisting integral terminal sliding mode control algorithm is proposed for a quad-rotor unmanned aerial vehicle (UAV).
Xinxin Chen
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source