Results 91 to 100 of about 51,947 (297)

The Approach of Voyager 1 to the Termination Shock [PDF]

, 2003
From 2001 to 2002 the anomalous cosmic ray (ACR) He intensity at 52 MeV/nuc increased by a factor of ∼2.2 at Voyager 1. The increase was larger at lower energies, indicating that Voyager 1 was 7.5±2.2 AU closer to the termination shock in 2002.
Stone, E. C., Cummings, A. C.
core  

Hybrid Simulations of Interstellar Pickup Ions at the Solar Wind Termination Shock Revisited

The Astrophysical Journal
We revisit previous hybrid simulations of the heating and acceleration of interstellar pickup ions (PUIs) at the solar wind termination shock. In previous simulations, a relatively cold initial distribution of PUIs was assumed; and while the resulting ...
Joe Giacalone, M. Kornbleuth, M. Opher, M. Gkioulidou, J. Köta, E. Puzzoni, J. D. Richardson, G. P. Zank   +7 more
doaj   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

A “Valley” in Heliospheric Energetic Particle Intensities and Implications for a New Horizons Encounter with the Solar Wind Termination Shock

The Astrophysical Journal
We analyze ∼40–200 keV energetic particle observations from the Pluto Energetic Particle Spectrometer Science Investigation (PEPSSI) on board the New Horizons (NH) spacecraft from 2007 to 2024 and compare them with similar measurements from the Low ...
Romina Nikoukar, Matthew E. Hill, Konstantinos Dialynas, Stamatios M. Krimigis, Lawrence E. Brown, Peter Kollmann, Robert D. Decker, Jerry W. Manweiler, W. Spencer Reeve, Vladimir Florinski, Ming Zhang, John Richardson, Merav Opher, Joe Giacalone, Laxman Adhikari, Pontus C. Brandt, Fernando Carcaboso, John F. Cooper, Heather A. Elliott, Robert Gold, Dennis Haggerty, Douglas C. Hamilton, Jozsef Kota, David Lario, Scott Lasley, Ralph McNutt Jr., Donald G. Mitchell, Parisa Mostafavi, Joel Parker, Andrew R. Poppe, Erick Powell, Elena Provornikova, Kelsi N. Singer, Justyna M. Sokół, S. Alan Stern, Anne J. Verbiscer, Bingbing Wang, Lingling Zhao   +37 more
doaj   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Injection Process of Pickup Ion Acceleration at an Oblique Heliospheric Termination Shock

The Astrophysical Journal Letters
The injection process of pickup ion acceleration at a heliospheric termination shock is investigated. Using two-dimensional fully kinetic particle-in-cell simulation, accelerated pickup ions are self-consistently reproduced by tracking long time ...
Shuichi Matsukiyo, Yosuke Matsumoto
doaj   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

The Fermi bubbles as starburst wind termination shocks [PDF]

Monthly Notices of the Royal Astronomical Society: Letters, 2014
Abstract The enhanced star formation in the inner 100 pc of the Galaxy launches a superwind at ∼1600 km s-1 for M82-like parameters. The ram pressure of the wind is very low compared to more powerful starburst winds. I show that halo gas stops the wind a few kpc from the Galactic Centre.
openaire   +2 more sources

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Visualization of Shock Wave Phenomenon around a Sharp Cone Model at Hypersonic Mach Number in a Shock Tunnel using High Speed Schlieren Facility

Journal of Applied Fluid Mechanics, 2019
The flow field around a Sharp cone model configuration has been investigated by means of Schlieren facility in hypersonic shock tunnel. The time dependent evolution of flow around a cone of angle 11.38° with base radius of 150mm has been visualized ...
M. Saiprakash, C. Senthil Kumar, G. K. Sunil, S. P. Rampratap, V. Shanmugam, G. Balu   +5 more
doaj   +2 more sources