Results 41 to 50 of about 51,947 (297)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

The influence of wall and shock curvature on shock reflection processes

open access: yes, 2022
S.543-549 : Abb.,Tab.,Lit.The paper deals with the transition conditions from regular to irregular two-dimensional shock wave reflection at a convex curved obstacle in air and with the subsequent modes of irregular reflection determined by these ...
Heilig, W.
core  

Usefulness of lead repositioning from left to right sternal border for a patient with subcutaneous implantable cardioverter defibrillator showing high defibrillation threshold

open access: yesJournal of Arrhythmia, 2019
A 62‐year‐old man with Brugada syndrome underwent subcutaneous implantable cardioverter defibrillator implantation. The lead was positioned along the left sternal border and defibrillation threshold (DFT) testing was performed.
Yasushi Wakabayashi   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

On the maximum energy of protons in the hotspots of AGN jets [PDF]

open access: yesEPJ Web of Conferences, 2019
We study particle acceleration and magnetic field amplification in the termination shocks (hotspots) of radiogalaxy jets. The cut-off of the synchrotron spectrum in the hotspots of powerful radiogalaxies is typically observed between infrared and optical
Araudo Anabella T.   +3 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Economic assessment of SRM under socio-political and geophysical tipping dynamics

open access: yesEnvironmental Research: Climate
Solar radiation modification (SRM) is increasingly discussed as a policy response to worsening climate impacts and stalled mitigation progress. Yet the viability of SRM hinges on its long-term governance, particularly the risk of abrupt and permanent ...
Francisco Estrada   +6 more
doaj   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

Particles acceleration at solar wind termination shock

open access: yes, 2020
A selfconsistent time dependent model is developed to study anomalous cosmic ray (ACR) acceleration at the heliospheric termination shock in the upwind direction and the shock modification under the influence of pickup protons and ACRs.
L T Ksenofontov, E G Berezhko
core  

How interacting winds shape the mechanical feedback of massive star clusters over millions of years

open access: yesAstronomy & Astrophysics
In recent years, massive star cluster environments have proved to be bright sources of very-high-energy γ-rays, in particular young clusters that are powered by the winds interacting in their cores.
Vieu T., Härer L., Reville B.
doaj   +1 more source

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