Results 1 to 10 of about 90,000 (258)

Construction of sodium alginate/trehalose/wheat starch ternary complex and its effects on storage stability of frozen dough system [PDF]

Food Chemistry: X
In order to improve the quality of frozen dough, a calcium alginate-coated sodium alginate/trehalose/wheat starch ternary complex was designed in this paper.
Tongchao Su, Wenkai Du, Jie Zeng, Haiyan Gao, Benguo Liu   +4 more
doaj   +4 more sources

A comprehensive kinetic model for ternary complex catalysis. [PDF]

Sci Rep, 2022
Ternary-complex directed enzyme catalysis underlies a vast array of biological processes and several clinical therapies including growth hormones, interferon, and heparin. Recently, interest in ternary catalysis drugs has increased significantly with the rapid expansion of research new technologies such as bispecific antibodies and proteolysis ...
Douglass EF, Miller CJ.
europepmc   +4 more sources

Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation [PDF]

Nature Communications, 2023
Targeted protein degradation via “hijacking” of the ubiquitin-proteasome system using proteolysis targeting chimeras (PROTACs) has evolved into a novel therapeutic modality.
Ryan P. Wurz, Huan Rui, Ken Dellamaggiore, Sudipa Ghimire-Rijal, Kaylee Choi, Kate Smither, Albert Amegadzie, Ning Chen, Xiaofen Li, Abhisek Banerjee, Qing Chen, Dane Mohl, Amit Vaish   +12 more
doaj   +2 more sources

Construction and Characterization of Emulsions Stabilized by Whey Protein Isolate-Naringin-Sodium Alginate Ternary Complex [PDF]

Foods
This study constructed ternary complexes of whey protein isolate (WPI), naringin (NAR), and sodium alginate (SA) and their stabilized emulsions, and characterized their physicochemical properties.
Si Chen, Mengmeng Wei, Guoyang Liu, Benguo Liu   +3 more
doaj   +2 more sources

Interaction mechanisms in cassava starch–hemicellulose–sinapic acid ternary complex [PDF]

Food Chemistry: X
This research explores the mechanisms underlying the interactions within the cassava starch (CS)-hemicellulose (HE)-sinapic acid (EA) ternary complex.
Guangjia Lv, Dehai Li, Chengsen Hou, Mingsen Wang, Xuan Zhang, Wendi Zhang, Yihong Bao, Yutong Zhang, Yanjun Zhang   +8 more
doaj   +2 more sources

Suitable Promoter for DNA Vaccination Using a pDNA Ternary Complex [PDF]

Pharmaceutics
In this study, we evaluated the effect of several promoters on the transfection activity and immune-induction efficiency of a plasmid DNA (pDNA)/polyethylenimine/γ-polyglutamic acid complex (pDNA ternary complex). Model pDNAs encoding firefly luciferase (
Tomoaki Kurosaki, Hiroki Nakamura, Hitoshi Sasaki, Yukinobu Kodama   +3 more
doaj   +2 more sources

Positive allosteric modulation of a GPCR ternary complex. [PDF]

Sci Adv
Abstract The activation of a G protein-coupled receptor (GPCR) leads to the formation of a ternary complex between agonist, receptor, and G protein that is characterised by high-affinity binding. Allosteric modulators bind to a distinct binding site from the orthosteric agonist and can modulate both the affinity and ...
Burger WAC, Draper-Joyce CJ, Valant C, Christopoulos A, Thal DM.   +4 more
europepmc   +3 more sources

Improving the Solubilization and Bioavailability of Arbidol Hydrochloride by the Preparation of Binary and Ternary β-Cyclodextrin Complexes with Poloxamer 188

Pharmaceuticals, 2021
In the current study, the effect of poloxamer 188 on the complexation efficiency and dissolution of arbidol hydrochloride (ADL), a broad-spectrum antiviral agent, with β-cyclodextrin (β-CD) was investigated.
Md. Khalid Anwer, Muzaffar Iqbal, Mohammad Muqtader Ahmed, Mohammed F. Aldawsari, Mohd Nazam Ansari, Essam Ezzeldin, Nasr Y. Khalil, Raisuddin Ali   +7 more
doaj   +1 more source

Formation and characterization of noncovalent ternary complexes based on whey protein concentrate, high methoxyl pectin, and phenolic acid

Journal of Dairy Science, 2022
: Protein-polysaccharide-polyphenol noncovalent ternary complexes possess unique physicochemical, structural, and functional properties. In the present study, ternary complexes based on whey protein concentrate (WPC; 2%, wt/vol) and high methoxyl pectin (
Yuanyuan Zhang, Siyao Li, Yang Yang, Cuina Wang, Tiehua Zhang   +4 more
doaj   +1 more source

Evaluation of transgene expression characteristics and DNA vaccination against melanoma metastasis of an intravenously injected ternary complex with biodegradable dendrigraft poly-L-lysine in mice

Drug Delivery, 2021
We developed a biocompatible splenic vector for a DNA vaccine against melanoma. The splenic vector is a ternary complex composed of plasmid DNA (pDNA), biodegradable dendrigraft poly-L-lysine (DGL), and γ-polyglutamic acid (γ-PGA), the selective uptake ...
Yukinobu Kodama, Ayako Tokunaga, Junya Hashizume, Hiroo Nakagawa, Hitomi Harasawa, Tomoaki Kurosaki, Tadahiro Nakamura, Koyo Nishida, Mikiro Nakashima, Mitsuru Hashida, Shigeru Kawakami, Hitoshi Sasaki   +11 more
doaj   +1 more source