Results 21 to 30 of about 90,000 (258)

New Insights in Thrombin Inhibition Structure–Activity Relationships by Characterization of Octadecasaccharides from Low Molecular Weight Heparin

Molecules, 2017
Low Molecular Weight Heparins (LMWH) are complex anticoagulant drugs that mainly inhibit the blood coagulation cascade through indirect interaction with antithrombin.
Pierre A. J. Mourier, Olivier Y. Guichard, Fréderic Herman, Philippe Sizun, Christian Viskov   +4 more
doaj   +1 more source

Sensitive Hg²⁺ Sensing via Quenching the Fluorescence of the Complex between Polythymine and 5,10,15,20-tetrakis(N-methyl-4-pyridyl) Porphyrin (TMPyP)

Sensors, 2018
The interaction between polythymine (dTn) and 5,10,15,20-tetrakis(N-methyl-4-pyridyl) porphyrin (TMPyP) was systematically studied using various techniques. dTn remarkably enhanced the fluorescence intensity of TMPyP as compared to other oligonucleotides.
Daohong Wu, Yaliang Huang, Shengqiang Hu, Xinyao Yi, Jianxiu Wang   +4 more
doaj   +1 more source

Extraction-Chromogenic System for Cobalt Based on 5-Methyl-4-(2-thiazolylazo)resorcinol and Benzalkonium Chloride

Acta Chimica Slovenica, 2021
The interaction between CoII and 5-methyl-4-(2-thiazolylazo)-resorcinol (MTAR) was studied in a water-chloroform system, in the presence or absence of benzalkonium chloride (BZC) as a cationic ion-association reagent. The optimum pH, concentration of the
Danail Georgiev Hristov, Petya Vassileva Racheva, Galya Konstantinova Toncheva, Kiril Blazhev Gavazov   +3 more
doaj   +1 more source

Development of a DNA Vaccine for Melanoma Metastasis by Inhalation Based on an Analysis of Transgene Expression Characteristics of Naked pDNA and a Ternary Complex in Mouse Lung Tissues

Pharmaceutics, 2020
The present study investigated a pulmonary delivery system of plasmid DNA (pDNA) and its application to melanoma DNA vaccines. pCMV-Luc, pEGFP-C1, and pZsGreen were used as a model pDNA to evaluate transfection efficacy after inhalation in mice.
Yukinobu Kodama, Mikiro Nakashima, Tadayuki Nagahara, Natsuko Oyama, Junya Hashizume, Hiroo Nakagawa, Hitomi Harasawa, Takahiro Muro, Tomoaki Kurosaki, Chikamasa Yamashita, Mitsuru Hashida, Takashi Kitahara, Hitoshi Sasaki, Shigeru Kawakami, Tadahiro Nakamura   +14 more
doaj   +1 more source

Playing with Opening and Closing of Heterocycles: Using the Cusmano-Ruccia Reaction to Develop a Novel Class of Oxadiazolothiazinones, Active as Calcium Channel Modulators and P-Glycoprotein Inhibitors

Molecules, 2014
As a result of the ring-into-ring conversion of nitrosoimidazole derivatives, we obtained a molecular scaffold that, when properly decorated, is able to decrease inotropy by blocking L-type calcium channels. Previously, we used this scaffold to develop a
Domenico Spinelli, Roberta Budriesi, Barbara Cosimelli, Elda Severi, Matteo Micucci, Massimo Baroni, Fabio Fusi, Pierfranco Ioan, Simon Cross, Maria Frosini, Simona Saponara, Rosanna Matucci, Camillo Rosano, Maurizio Viale, Alberto Chiarini, Emanuele Carosati   +15 more
doaj   +1 more source

Complexes in Ternary Cholesterol-Phospholipid Mixtures [PDF]

Biophysical Journal, 2005
Recent work by Veatch and Keller has described micron-scale liquid-liquid immiscibility in giant unilamellar vesicles composed of ternary mixtures of cholesterol, dipalmitoylphosphatidylcholine (DPPC), and dioleoylphosphatidylcholine (DOPC). Significantly, they do not observe micron-scale immiscibility in any of the three corresponding binary mixtures ...
openaire   +2 more sources

Formula Complexity of Ternary Majorities [PDF]

, 2012
It is known that any self-dual Boolean function can be decomposed into compositions of 3-bit majority functions. In this paper, we define a notion of a ternary majority formula, which is a ternary tree composed of nodes labeled by 3-bit majority functions and leaves labeled by literals. We study their complexity in terms of formula size. In particular,
openaire   +1 more source

Complex Formation in a Liquid-Liquid Extraction System Containing Vanadium(IV/V), 2,3-Dihydroxynaphtahlene and Thiazolyl Blue

Acta Chimica Slovenica, 2018
Liquid-liquid extraction systems for VIV/V containing 2,3-dihydroxynaphtahlene (DN) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (thiazolyl blue, MTT) were studied. The optimum conditions for VIV and VV extraction were found.
Galya K. Toncheva, Zlatimir T. Zhelev, Vassil B. Delchev, Kiril Blazhev Gavazov   +3 more
doaj   +1 more source

Preparation, and Luminescence Properties of SiO2@Sm(MABA-Si)phen Core-Shell Structure Nanometer Composite

MATEC Web of Conferences, 2018
A novel ternary samarium complex was prepared using HOOCC6H4N(CONH(CH2)3Si- (OCH2CH3)3)2 (MABA-Si) as first ligand, and phen as second ligand. The corresponding SiO2@Sm(MABA-Si)phen core-shell structure nanometer composite was synthesized as well, and ...
Feng Li-Na, Li Wen-Xian, Bao Jin-Rong
doaj   +2 more sources

Crystal structure of a nuclear actin ternary complex [PDF]

Proceedings of the National Academy of Sciences, 2016
Significance Actin is a prominent component of the cytoskeleton in the cytoplasm of eukaryotic cells. Its presence in the nucleus was once considered controversial. However, it is now widely accepted that nuclear actin (N-actin) is a constitutive subunit of several chromatin-remodeling complexes. Yet, the specific structure of N-actin and how
Tingting, Cao, Lingfei, Sun, Yuxiang, Jiang, Shanjin, Huang, Jiawei, Wang, Zhucheng, Chen   +5 more
openaire   +2 more sources