Results 211 to 220 of about 90,000 (258)
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Characterization of the FKBP·Rapamycin·FRB Ternary Complex
Journal of the American Chemical Society, 2005Rapamycin is an important immunosuppressant, a possible anticancer therapeutic, and a widely used research tool. Essential to its various functions is its ability to bind simultaneously to two different proteins, FKBP and mTOR. Despite its widespread use, a thorough analysis of the interactions between FKBP, rapamycin, and the rapamycin-binding domain ...
Laura A, Banaszynski +2 more
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Ets ternary complex transcription factors
Gene, 2004The three ternary complex factors (TCFs) Elk-1, Net and Sap-1 form a subfamily of the E twenty-six (Ets) domain transcription factors. Their characteristic property is the ability to form a ternary nucleoprotein complex with the serum response factor (SRF) over the serum response element (SRE) of the c-fos promoter.
Buchwalter, Gilles +2 more
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On the State Complexities of Ternary Codes
1999The paper studies self-orthogonal codes over GF(3). The state complexities ofs uch codes of lengths ≤ 20 with efficient coordinate ordering are found.
Sylvia B. Encheva, Gérard D. Cohen
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Ternary Ligand−Zinc−Hydroxamate Complexes
Inorganic Chemistry, 2004Because of the importance of the hydroxamic acid functional group in zinc protease inhibitors, we have measured the stability constants of the ternary complex LMG, where L is series of tridentate and tetradentate ligands containing amino, carboxylate, pyridyl, and/or imidazolyl groups as enzyme models and G is the guest molecule, acetohydroxamate or N ...
Yu-Hung, Chiu +2 more
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Ternary complexes in analytical chemistry
Talanta, 1968Reactions between a complex AB and a third component C do not always proceed by a displacement mechanism governed by the energy difference of the chemical bonds A-B and A-C. The third component often becomes part of the complex, forming a mixed co-ordination sphere or ternary complex.
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Ternary complexes of liver alcohol dehydrogenase
Chemico-Biological Interactions, 2001Liver alcohol dehydrogenase (LADH; E.C. 1.1.1.1) provides an excellent system for probing the role of binding interactions with NAD(+) and alcohols as well as with NADH and the corresponding aldehydes. The enzyme catalyzes the transfer of hydride ion from an alcohol substrate to the NAD(+) cofactor, yielding the corresponding aldehyde and the reduced ...
Y, Pocker, J D, Page, H, Li, C C, Bhat
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Encapsulation and stabilization of lactoferrin in polyelectrolyte ternary complexes
Food Hydrocolloids, 2023Effective delivery of the bioactive protein, lactoferrin (LF), remains a challenge as it is sensitive to environmental changes and easily denatured during heating, restricting its application in functional food products. To overcome these challenges, we formulated novel polyelectrolyte ternary complexes of LF with gelatin (G) and negatively charged ...
Tiantian Lin +6 more
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Integrative Modeling of PROTAC-Mediated Ternary Complexes
Journal of Medicinal Chemistry, 2021Proteolysis-targeting chimeras (PROTACs), which selectively induce targeted protein degradation, represent an emerging drug discovery technology. Although numerous PROTACs have been reported, designing potent PROTACs still remains a great challenge, to some extent, due to insufficient structural data of Target-PROTAC-E3 ternary complexes. In this work,
Gaoqi Weng, Dan Li, Yu Kang, Tingjun Hou
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Ternary Complex Therapy for Autoimmune Disease
Hospital Practice, 1995Induction of an immune response is remarkably simple, involving the interaction of three components: processed antigen, an MHC class II molecule, and a CD4 T-cell receptor. Each part of this ternary complex represents a novel target for interventions that may block subsequent effector phenomena of autoimmune disease.
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Binary and ternary complexes of sulphamethoxazole
Monatshefte f�r Chemie Chemical Monthly, 1995The complex formation equilibria involved in the binary and ternary systemsM(II)-sulpha andM(II)-phen-sulpha were investigated by potentiometric titrations at 25°C and a ionic strength of 0.1N NaNO3 (M = Cu, Ni, Co, Zn;sulpha = sulphamethoxazole;phen = phenanthroline).
E. M. Shoukry +3 more
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