Results 61 to 70 of about 4,886 (206)
Isolation of Catharanthus roseus (L.) G. Don Nuclei and Measurement of Rate of Tryptophan decarboxylase Gene Transcription Using Nuclear Run-On Transcription Assay. [PDF]
PLoS ONE, 2015 BACKGROUND:An accurate assessment of transcription 'rate' is often desired to describe the promoter activity. In plants, isolation of transcriptionally active nuclei and their subsequent use in nuclear run-on assays has been challenging and therefore ...
Santosh Kumar, Sabhyata Bhatia
doaj +1 more source
Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi [PDF]
, 2015 Genomics has revolutionized the research on fungal secondary metabolite (SM) biosynthesis. To elucidate the molecular and enzymatic mechanisms underlying the biosynthesis of a specific SM compound, the important first step is often to find the genes that
Cacho, Ralph A. +2 more
core +1 more source
Plant, Cell &Environment, EarlyView.ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo +5 more
wiley +1 more source
Cross-family transcription factor interaction between MYC2 and GBFs modulates terpenoid indole alkaloid biosynthesis [PDF]
Journal of Experimental Botany, 2018 Biosynthesis of medicinally valuable terpenoid indole alkaloids (TIAs) in Catharanthus roseus is regulated by transcriptional activators such as the basic helix-loop-helix factor CrMYC2. However, the transactivation effects are often buffered by repressors, such as the bZIP factors CrGBF1 and CrGBF2, possibly to fine-tune the accumulation of cytotoxic ...
Xueyi, Sui +6 more
openaire +2 more sources
BMC Genomics, 2018 Background The medicinal plant, Catharanthus roseus (C. roseus), accumulates a wide range of terpenoid indole alkaloids (TIAs). Ethylene (ET) and methyl-jasmonate (MeJA) were previously reported as effective elicitors for the production of various ...
Ya-jie Pan +5 more
doaj +1 more source
Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families
Plant, Cell &Environment, EarlyView.ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor +4 more
wiley +1 more source
Plant Biology, EarlyView.Herbicide residues in soil disrupt plant–insect signalling, reducing the effectiveness of biological pest control. Abstract Plants under herbivore attack emit distinct blends of herbivore‐induced plant volatiles (HIPVs) which serve as signalling cues for predatory insects.
B. Fuchs, J. D. Blande, V. Weijola
wiley +1 more source
Transcriptome analysis in Catharanthus roseus leaves and roots for comparative terpenoid indole alkaloid profiles [PDF]
Journal of Experimental Botany, 2006 In Catharanthus roseus (L.) G. Don each tissue is known to produce a distinct spectrum of terpenoid indole alkaloids. Since the invaluable antineoplastic bisindole alkaloids are restricted to the aerial parts of the plant and do not occur in its underground tissues, identification of the structural and regulatory factors operating distinctly in the ...
Ashutosh K, Shukla +3 more
openaire +2 more sources
Frontiers in Plant Science, 2019 The Catharanthus roseus plant is the exclusive source of the valuable anticancer terpenoid indole alkaloids, vinblastine (VB) and vincristine (VC). The recent availability of transcriptome and genome resources for C.
Samuel Mortensen +8 more
doaj +1 more source
AlkaPlorer: A database‐driven explorer for natural alkaloids and derivatives
Journal of Integrative Plant Biology, Volume 68, Issue 5, Page 1384-1398, May 2026.The alkaloid database AlkaPlorer integrates over 130,000 compounds across 12,250 species. By linking chemical structures with biological and evolutionary data, it reveals how these molecules evolve and function. This platform serves as a vital resource for AI‐driven discovery in plant metabolism and modern drug development. ABSTRACT Alkaloids, renowned
Jiahao Li +5 more
wiley +1 more source