Results 61 to 70 of about 2,466 (171)

Identification and Functional Characterization of a Geraniol Synthase UrGES from Uncaria rhynchophylla

Plants
Uncaria rhynchophylla, a medicinal plant extensively used in traditional Chinese medicine, is an important plant source of terpenoid indole alkaloids (TIAs), but the mechanism of TIA biosynthesis at molecular level remains unclear. Geraniol synthase (GES)
Xinghui Liu, Wenqiang Chen, Linxuan Li, Detian Mu, Iain W. Wilson, Xueshuang Huang, Yahui Xiang, Lina Zhu, Limei Pan, Deyou Qiu, Qi Tang   +10 more
doaj   +1 more source

Jasmonic Acid Effect on the Fatty Acid and Terpenoid Indole Alkaloid Accumulation in Cell Suspension Cultures of Catharanthus roseus

Molecules, 2014
The stress response after jasmonic acid (JA) treatment was studied in cell suspension cultures of Catharanthus roseus. The effect of JA on the primary and secondary metabolism was based on changes in profiles of fatty acids (FA) and terpenoid indole ...
Guitele Dalia Goldhaber-Pasillas, Natali Rianika Mustafa, Robert Verpoorte   +2 more
doaj   +1 more source

Inhibition of jasmonic acid‐isoleucine conjugating enzyme JAR1 shifts the local and systemic leaf signals and metabolic profiles in Arabidopsis

New Phytologist, Volume 251, Issue 1, Page 424-437, July 2026.
Summary Jasmonates (JAs)‐mediated pathways are central signaling hubs in plant defense responses. However, the identification of mobile and nonmobile signals involved in downstream systemic signaling is still less studied. Here, we investigate the role of the jasmonic acid‐isoleucine (JA‐Ile) conjugating enzyme, JAR1, in shifting wound‐induced local ...
Ming Zeng, Axel Mithöfer
wiley   +1 more source

The Supporting Role of Natural Products as Effective Adjuvants in Cancer Immunotherapy

eFood, Volume 7, Issue 3, June 2026.
Natural products, as multi‐target and low‐toxicity adjuvants, enhance immune checkpoint inhibitor responses and reduce immune‐related adverse events through T cell reprogramming, microenvironment remodeling, and microbiota‐immune modulation. ABSTRACT Immune checkpoint inhibitors (ICIs) have revolutionized the treatment landscape of malignant tumors ...
Boyang Liu, Yubin Huang, Jianjun Deng, Zhijun Mao, Xue Bai, Longyang Ma, Jianhua Wang   +6 more
wiley   +1 more source

Ornamental Exterior versus Therapeutic Interior of Madagascar Periwinkle (Catharanthus roseus): The Two Faces of a Versatile Herb

The Scientific World Journal, 2015
Catharanthus roseus (L.) known as Madagascar periwinkle (MP) is a legendary medicinal plant mostly because of possessing two invaluable antitumor terpenoid indole alkaloids (TIAs), vincristine and vinblastine.
Naghmeh Nejat, Alireza Valdiani, David Cahill, Yee-How Tan, Mahmood Maziah, Rambod Abiri   +5 more
doaj   +1 more source

Bioactive Composition and Antioxidant and Glycemic‐Regulating Properties of Basella alba L. Leaf, Fruit, and Stem: GC–MS, FTIR, In Vitro and In Silico Insights

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
The bioactive composition, antioxidant capacity, and glycemic‐regulating properties of Basella alba L. leaf, fruit, and stem were comparatively analyzed using gas chromatography–mass spectrometry (GC–MS), Fourier‐transform infrared spectroscopy (FTIR), in vitro assays, and molecular docking analyses.
Shorna Das, Satyajit Roy Rony, Bidduth Kumar Sarkar, Sukalyan Kumar Kundu, Pradip Debnath   +4 more
wiley   +1 more source

Nutritional Composition, Odor‐Contributing Volatile Compounds, and Antioxidant Capacity of the Wild Edible Mushroom Entoloma clypeatum

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Nutritional composition, free amino acids, fatty acids, minerals, 5′ ‐nucleotides, volatile compounds, and antioxidant activities of Entoloma clypeatum. ABSTRACT Wild mushrooms are increasingly valued in diets for their nutrients and health benefits. The nutritional composition of Entoloma clypeatum, a wild mycorrhizal edible species that grows under ...
Cuiduan Wang, Zhuang Li, Xiaomin Yang, Jianhua Lv, Jinxiu Zhang   +4 more
wiley   +1 more source

Functional Metagenomics Insights Into the Allium ampeloprasum Rhizosphere Microbiome Under Different Fertilization Regimes

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Shotgun metagenomic sequencing was used to characterize the functional potential of the Allium ampeloprasum rhizosphere microbiome under chemical fertilizer (G1), biofertilizer (G2), and unfertilized (Bulk) soil (G3) management practices. This study revealed that different fertilization regimes altered microbial functional profiles.
Oluwaseun Emmanuel Shittu, Ben Jesuorsemwen Enagbonma, Olubukola Oluranti Babalola   +2 more
wiley   +1 more source

Genome-wide identification of TCP transcription factors and functional role of UrTCP4 in regulating terpenoid indole alkaloids biosynthesis in Uncaria rhynchophylla

Current Plant Biology
Uncaria rhynchophylla is a widely used Chinese herbal medicine known for its terpenoid indole alkaloids (TIAs), which help in treating hypertension. Teosinte branched 1/cycloidea/proliferating cell factors 1/2 (TCP) TFs have been shown to have a role in ...
Xinghui Liu, Yingying Shao, Detian Mu, Yu Zhou, Jialong He, Huan Zhao, Iain W. Wilson, Yao Zhang, Lina Zhu, Deyou Qiu, Qi Tang   +10 more
doaj   +1 more source

Development of efficient catharanthus roseus regeneration and transformation system using agrobacterium tumefaciens and hypocotyls as explants

BMC Biotechnology, 2012
Background As a valuable medicinal plant, Madagascar periwinkle (Catharanthus roseus) produces many terpenoid indole alkaloids (TIAs), such as vindoline, ajamlicine, serpentine, catharanthine, vinblastine and vincristine et al. Some of them are important
Wang Quan, Xing Shihai, Pan Qifang, Yuan Fang, Zhao Jingya, Tian Yuesheng, Chen Yu, Wang Guofeng, Tang Kexuan   +8 more
doaj   +1 more source