Results 281 to 290 of about 58,085 (320)

The thymus in autoimmune Myasthenia Gravis: Paradigm for a tertiary lymphoid organ

Revue Neurologique, 2013
In autoimmune Myasthenia Gravis (MG), a neuromuscular disease generally mediated by autoantibodies against the acetylcholine receptor (AChR), the muscle is the target organ of the autoimmune attack, while the thymus seems to be the primary production site of the autoantibodies.
J-M, Weiss, P, Cufi, R, Le Panse, S, Berrih-Aknin   +3 more
openaire   +2 more sources

Role of Fibroblast‐Immune Crosstalk in Kidney, Lung, and Skin Tertiary Lymphoid Structures

Immunological Reviews
Tertiary lymphoid structures (TLSs) are organized aggregates of lymphocytes, myeloid cells, and stromal cells that form at sites of inflammation, providing adaptive immune responses outside of secondary lymphoid organs (SLOs).
Amy Cross, Jennifer Shelley, Rebecca Newman, Jessica Strid, Alice E Denton   +4 more
semanticscholar   +1 more source

Tertiary Lymphoid Organs at the Center Stage of Skin's Humoral Immunity

Immunological Reviews
The skin is the outermost organ that serves as the host's live, microbiota‐inhabited physical border, evolved to cope with continuous confrontation by a wide variety of environmental elements.
I. Gribonika
semanticscholar   +1 more source

Abstract B081: Characterizing immune dysregulation and tertiary lymphoid structures in endometriosis: Pathogenic insights and therapeutic implications

Cancer immunology research
Endometriosis (EMS) is a prevalent systemic disorder impacting 10% of women of reproductive age, characterized by the growth of endometrial-like tissue outside the uterine cavity, chronic inflammation, and fibrosis, leading to pain, infertility, and ...
Ariana F Rahman, K. Khazaie, Elika D. Javaheri, Y. Woldeamanuel   +3 more
semanticscholar   +1 more source

Mice with lymphatic dysfunction develop pathogenic lung tertiary lymphoid organs that model an autoimmune emphysema phenotype of COPD

American Journal of Physiology - Lung cellular and Molecular Physiology
We have previously shown that mice with loss of C-type lectin-like type II (CLEC2), which have lymphatic dysfunction due to the role of CLEC2 in platelets for maintaining separation between the venous and lymphatic system, develop lung tertiary lymphoid ...
Barbara Summers, Kihwan Kim, Anjali Trivedi, Tyler M. Lu, Sean Houghton, J. Palmer-Johnson, J. Rojas-Quintero, Juan Cala-García, Tania Pannellini, F. Polverino, Raphaël Lis, H. O. Reed   +11 more
semanticscholar   +1 more source

Abstract 4220: Combined light sheet and multispectral imaging facilitates the detection of tumor-associated tertiary lymphoid structures in the KP NSCLC model

Cancer Research
Tertiary lymphoid structures (TLS) have recently emerged as a predictive biomarker in cancer immunotherapy. Their consideration in preclinical drug development is impeded by rare and transient appearance and random distribution, making them difficult ...
Nils O'Brien, B. Appelt, Marie-Lena Moerbitz, Joerg P J Mueller, F. Herting, P. Umaña, Claudio Murgia, S. Colombetti, Thomas Pöschinger   +8 more
semanticscholar   +1 more source

Radiation therapy‐associated toxicity: Etiology, management, and prevention

Ca-A Cancer Journal for Clinicians, 2021
Kyle Wang
exaly  

Single-cell spatial transcriptomics of tertiary lymphoid organ-like structures in human atherosclerotic plaques

Nature Cardiovascular Research
Zhichao Lai, Deqiang Kong, Qingsong Li, Yue Wang, Kang Li, Xiaohan Duan, Jiang Shao, Yiyun Xie, Junye Chen, Tianjing Zhang, Yuyao Feng, Haohao Deng, Jiaxian Wang, Chaonan Wang, Keqiang Shu, Hongmei Zhao, Hanze Du, Congwei Jia, Huanyu Dai, Lizhi Xie, Jianlin Liu, Xujiao Luo, Lin Wang, Leyin Xu, Zhan Zhu, Xiangling Lei, Yuru Wang, Yixuan Yang, Yanan Liu, Yuyu Liang, Yang Yang, Jun Xie, Bao Liu, Ziqing Deng, Xin Liu   +34 more
semanticscholar   +1 more source

Magnetic resonance linear accelerator technology and adaptive radiation therapy: An overview for clinicians

Ca-A Cancer Journal for Clinicians, 2022
William A Hal, X Allen Li, Daniel A Low
exaly  

[Meningeal tertiary lymphoid organs: Major actors in intrathecal autoimmunity].

Revue neurologique, 2015
Multiple sclerosis (MS) is characterized by an intrathecal synthesis of immunoglobulins synthesized by B-cell clones and by a brain infiltrate of clonal T-cells. The clonal maturation of these lymphocytes takes place in tertiary lymphoid organs (TLO) developed in the intrathecal compartment.
openaire   +1 more source