Results 271 to 280 of about 29,370 (346)

TMIC-39. SPATIAL MULTIOMICS PROFILING REVEALS HETEROGENEITY OF B:T CELL INTERACTIONS AND PLASMA CELL FORMATION IN TERTIARY LYMPHOID STRUCTURES IN HUMAN GLIOMAS [PDF]

Pinar Cakmak, Jennifer H. Lun, Aakanksha Singh, Jadranka Macas, Michael C. Burger, Lucie Marie Hasse, Elke Hattingen, Miriam Köhler, Jonathan Schupp, Tatjana Starzetz, Eike Steidl, Karl H. Plate, Yvonne Reiss, Katharina Imkeller   +13 more
openalex   +1 more source

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

Advanced Science, Volume 13, Issue 7, 3 February 2026.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu, Jiabi Liang, Linda Zeng, Shuping Zhong, Xueling Fang, Yating Xu, Yongjian Wu, Xi Huang   +7 more
wiley   +1 more source

B cells and tertiary lymphoid structures in cancer therapy response. [PDF]

BJC Rep
Hegoburu A, Amer M, Frizelle F, Purcell R.   +3 more
europepmc   +1 more source

Heterogeneity of Tertiary Lymphoid Structures and Plasma Cells in PDAC with and Without Lymph Node Metastasis. [PDF]

Cancers (Basel)
Wang M, Zhang L, Chen H.
europepmc   +1 more source

Beyond bacterial defences: the role of lysozyme in cancer

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Lysozyme (LYZ) is a multi‐functional secreted factor that encompasses both antibacterial and immunomodulatory functions. Emerging evidence highlights its complex role in tumour progression by directly influencing tumour cells and modulating the immune microenvironment.
Lei Wang, Qian Dong, Fuchu He, Zhiwen Gu, Aihua Sun   +4 more
wiley   +1 more source

Th17-like cells and immunosuppressive macrophages infiltrate tertiary lymphoid structures with distinct maturation status in soft-tissue sarcoma. [PDF]

Cell Death Dis
Petroni G, Scolari F, Scoccianti G, Palomba A, Greto D, Romagnoli S, Palchetti I, Bernini A, Caliman E, Polvani S, Nozzoli F, Menicacci B, Nannini G, Campanacci DA, Pillozzi S, Antonuzzo L.   +15 more
europepmc   +1 more source

Causal Effect of Dietary Patterns on Cerebral Small Vessel Disease: A Mendelian Randomization Study

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
This Mendelian randomization (MR) study reveals causal links between dietary factors and cerebral small vessel disease (CSVD) neuroimaging markers. Genetically predicted higher polyunsaturated fatty acid (PUFA) levels reduce white matter hyperintensity volume, while monounsaturated fatty acid (MUFA) intake lowers lobar brain microbleeds (BMB) risk.
Yong Zeng, Ziqian Zhao, Hongyan Liu, Yijun Zeng, Song Xu, Shanjing Nie   +5 more
wiley   +1 more source

An MRI-based model for preoperative prediction of tertiary lymphoid structures in patients with gallbladder cancer. [PDF]

Insights Imaging
Xu Y, Li Z, Zhi W, Yang Y, Ouyang J, Zhou Y, Ma Z, Wang S, Xie L, Ying J, Zhou J, Zhao X, Ye F.   +12 more
europepmc   +1 more source

Advances in the Role of Adipose Tissue in Promoting Injury Repair and Resist Infection

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background In recent years, adipose tissue (AT) transplantation has increasingly been noticed by many people in the field of tissue repair and regeneration. Accumulating evidence demonstrates that AT exerts dual functions in promoting tissue repair and conferring anti‐infective properties, with distinct biological effects attributed to its ...
Xi Duan, Run Li, Lei Fu, Jiali Yang, Zhean Zhan   +4 more
wiley   +1 more source

Tertiary lymphoid structures in esophageal cancer: a novel target for immunotherapy. [PDF]

Front Immunol
Zhai K, Ma Y, Gao X, Ru K, Zhao M.
europepmc   +1 more source