Results 1 to 10 of about 258,881 (309)
Tertiary structure assessment at CASP15. [PDF]
Proteins, 2023 AbstractThe results of tertiary structure assessment at CASP15 are reported. For the first time, recognizing the outstanding performance of AlphaFold 2 (AF2) at CASP14, all single‐chain predictions were assessed together, irrespective of whether a template was available.
Simpkin AJ +7 more
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Protein Macrocyclization for Tertiary Structure Stabilization. [PDF]
Chembiochem, 2021 AbstractProteins possess unique molecular recognition capabilities and enzymatic activities, features that are usually tied to a particular tertiary structure. To make use of proteins for biotechnological and biomedical purposes, it is often required to enforce their tertiary structure in order to ensure sufficient stability under the conditions ...
Haim A, Neubacher S, Grossmann TN.
europepmc +5 more sources
Modeling the Tertiary Structure of the Rift Valley Fever Virus L Protein [PDF]
Molecules, 2019 A tertiary structure governs, to a great extent, the biological activity of a protein in the living cell and is consequently a central focus of numerous studies aiming to shed light on cellular processes central to human health. Here, we aim to elucidate
Gideon K. Gogovi +5 more
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Prediction of Protein Tertiary Structure via Regularized Template Classification Techniques [PDF]
Molecules, 2020 We discuss the use of the regularized linear discriminant analysis (LDA) as a model reduction technique combined with particle swarm optimization (PSO) in protein tertiary structure prediction, followed by structure refinement based on singular value ...
Óscar Álvarez-Machancoses +2 more
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Frontiers in Microbiology, 2023 The functional significance of the HIV-1 Antisense Protein (ASP) has been a paradox since its discovery. The expression of this protein in HIV-1-infected cells and its involvement in autophagy, transcriptional regulation, and viral latency have ...
Balakumaran Sathiyamani +11 more
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Molecular and in silico analysis of the coat protein of hibiscus chlorotic ringspot virus isolates [PDF]
Journal of Crop Protection, 2023 Hibiscus chlorotic ringspot virus (HCRSV), genus Betacarmovirus, family Tombusviridae, is a common pathogen of hibiscus plants in tropical and subtropical regions. During 2020-2021, leaf samples of Chinese hibiscus Hibiscus rosa-sinensis L. with mottling
Nadia Mosharaf +4 more
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Frontiers in Microbiology, 2023 The COVID-19 pandemic has resulted in the implementation of strict mitigation measures that have impacted the transmission dynamics of human respiratory syncytial virus (HRSV).
Chi-yu Guo +8 more
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Biomolecules, 2022 With the debut of AlphaFold2, we now can get a highly-accurate view of a reasonable equilibrium tertiary structure of a protein molecule. Yet, a single-structure view is insufficient and does not account for the high structural plasticity of protein ...
Fardina Fathmiul Alam, Amarda Shehu
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Evaluating Autoencoder-Based Featurization and Supervised Learning for Protein Decoy Selection
Molecules, 2020 Rapid growth in molecular structure data is renewing interest in featurizing structure. Featurizations that retain information on biological activity are particularly sought for protein molecules, where decades of research have shown that indeed ...
Fardina Fathmiul Alam +2 more
doaj +1 more source
Foods, 2023 The limited solubility and stability of pea proteins hinder their utilization in liquid formulations. In this study, protein glutaminase (PG) was employed to modify pea protein isolates (PPIs) and obtain deamidated PPI with varying degrees of deamidation
Lijuan Luo +6 more
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