Results 21 to 30 of about 291,656 (309)
A triphosphate tunnel metalloenzyme from pear (PbrTTM1) moonlights as an adenylate cyclase
Frontiers in Plant Science, 2023 Adenylyl cyclase (AC) is the vital enzyme for generating 3′,5′-cyclic adenosine monophosphate, an important signaling molecule with profound nutritional and medicinal values.
Ye Yuan +14 more
doaj +1 more source
RNA tertiary structure modeling with BRiQ potential in CASP15
, 2023 We describe the modeling method for RNA tertiary structures employed by team AIchemy_RNA2 in the 15th Critical Assessment of Structure Prediction (CASP15). The method consists of the following steps.
Chen, K +7 more
core +1 more source
Characterization of transcription profile and structural properties of avian NK-lysin
Poultry Science, 2020 This study aimed to determine the transcription profile of NK-lysin gene in native chickens. Moreover, it was targeted toward determining the primary, three-dimensional, and molecular dynamic structures of NK-lysin and granulysin peptides to understand ...
Maged M. Mahmoud, Haitham A. Yacoub
doaj +1 more source
Two triphosphate tunnel metalloenzymes from apple exhibit adenylyl cyclase activity
Frontiers in Plant Science, 2022 Adenylyl cyclase (AC) is the key catalytic enzyme for the synthesis of 3′,5′-cyclic adenosine monophosphate. Various ACs have been identified in microorganisms and mammals, but studies on plant ACs are still limited.
Ye Yuan +13 more
doaj +1 more source
Reducing Ensembles of Protein Tertiary Structures Generated De Novo via Clustering
Molecules, 2020 Controlling the quality of tertiary structures computed for a protein molecule remains a central challenge in de-novo protein structure prediction. The rule of thumb is to generate as many structures as can be afforded, effectively acknowledging that ...
Ahmed Bin Zaman +3 more
doaj +1 more source
A novel mutation in the cathepsin C (CTSC) gene in Iranian family with Papillon‐Lefevre syndrome
Clinical and Experimental Dental Research, 2021 Objectives In this study, we analyzed the whole exomes of CTSC gene in a family with history of PLS. Materials and methods Genomic DNA was extracted from peripheral blood and genotype analysis was performed.
Mahmoud Ghanei +4 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2021 Aptamers are short, single-stranded DNA or RNA oligonucleotide molecules that function as synthetic analogs of antibodies and bind to a target molecule with high specificity.
Dmitry Morozov +18 more
doaj +1 more source
Pervasive tertiary structure in the dengue virus RNA genome. [PDF]
Proc Natl Acad Sci U S A, 2018 Dethoff EA +10 more
europepmc +2 more sources
Generative Adversarial Learning of Protein Tertiary Structures
Molecules, 2021 Protein molecules are inherently dynamic and modulate their interactions with different molecular partners by accessing different tertiary structures under physiological conditions. Elucidating such structures remains challenging.
Taseef Rahman +3 more
doaj +1 more source
Plants, 2016 The two major storage proteins identified in Brassica napus (canola) were isolated and studied for their molecular composition, structural characteristics and the responses of structural features to the changes in pH and temperature.
Suneru P. Perera +2 more
doaj +1 more source