Results 21 to 30 of about 7,456,122 (302)

RNA tertiary structure modeling with BRiQ potential in CASP15

, 2023
We describe the modeling method for RNA tertiary structures employed by team AIchemy_RNA2 in the 15th Critical Assessment of Structure Prediction (CASP15). The method consists of the following steps.
Chen, K, Yaoqi Zhou, Xiong, P, Sheng Wang, Ke Chen, Zhou, Y, Wang, S, Peng Xiong   +7 more
core   +1 more source

Use of the 2D ¹H-¹³C HSQC NMR Methyl Region to Evaluate the Higher Order Structural Integrity of Biopharmaceuticals

Molecules, 2021
The higher-order structure (HOS) of protein therapeutics is directly related to the function and represents a critical quality attribute. Currently, the HOS of protein therapeutics is characterized by methods with low to medium structural resolution ...
Tsang-Lin Hwang, Dipanwita Batabyal, Nicholas Knutson, Mats Wikström   +3 more
doaj   +1 more source

Loop Entropy Assists Tertiary Order: Loopy Stabilization of Stacking Motifs

Entropy, 2011
The free energy of an RNA fold is a combination of favorable base pairing and stacking interactions competing with entropic costs of forming loops. Here we show how loop entropy, surprisingly, can promote tertiary order.
Daniel P. Aalberts
doaj   +1 more source

Structural and Functional Exploration of UTS2B Gene for a Possible Role in Poultry Ascites Syndrome: In Silico Analysis [PDF]

Poultry Science Journal
Ascites syndrome is a multifactorial disease in poultry, associated with high mortality and significant economic losses. Genomic studies have identified UTS2B gene as a candidate gene associated with ascites syndrome in poultry.
Mostafa Ghaderi-Zefrehei, Effat Nasre Esfahani, Hamed Sharyarpour, Mustafa Muhaghegh Dolatabay   +3 more
doaj   +1 more source

Morphology of sodium deoxycholate-solubilized apolipoprotein B-100 using negative stain and vitreous ice electron microscopy

Journal of Lipid Research, 2000
The primary and secondary structures of apolipoprotein B-100 (apoB-100) are well established. Previous morphological studies have suggested that apoB is a long, flexible, threadlike molecule that encircles the low density lipoprotein (LDL) particle ...
Donald L. Gantz, Mary T. Walsh, Donald M. Small   +2 more
doaj   +1 more source

STRUCTURAL SIMILARITY OF CheY-LIKE PROTEINS

TASK Quarterly, 2016
The problem of structural similarity of polypeptide chains of low sequence similarity representing a similar 3D structural form has been the object of analysis of researchers engaged in the protein folding problem.
MATEUSZ BANACH, LESZEK KONIECZNY, IRENA ROTERMAN   +2 more
doaj   +1 more source

Influence of ground-state structure and Mg2+ binding on folding kinetics of the guanine-sensing riboswitch aptamer domain [PDF]

, 2011
Riboswitch RNAs fold into complex tertiary structures upon binding to their cognate ligand. Ligand recognition is accomplished by key residues in the binding pocket.
Julia Wirmer-Bartoschek, Anna Wacker, Wirmer-Bartoschek, J., Schwalbe, H., Wacker, A., Wirmer-Bartoschek, Julia, Eberhart Warkentin, Buck, Janina, Warkentin, E., Wacker, Anna, Wöhnert, Jens, Schwalbe, Harald, Harald Schwalbe, Wöhnert, J., Jens Wöhnert, Warkentin, Eberhart, Buck, J., Janina Buck   +17 more
core   +1 more source

Collaborative national evaluation of Signposts: A professional development resource for new tertiary teachers [PDF]

, 2010
This report describes the context, process and outcomes of a formal evaluation of Signposts, a professional development resource for new tertiary teachers, originally developed in ...
Fraser, Cath, Reid, Pat, Van Toor, Helen, Fester, Victor, Honeyfield, Judy, Fitchett, Liz, Shaw, Linda, McMillan, Adam, Robertson-Welsh, Debra   +8 more
core   +1 more source

Structural 3D Domain Reconstruction of the RNA Genome from Viruses with Secondary Structure Models

Viruses, 2021
Three-dimensional RNA domain reconstruction is important for the assembly, disassembly and delivery functionalities of a packed proteinaceus capsid. However, to date, the self-association of RNA molecules is still an open problem. Recent chemical probing
Simón Poblete, Horacio V. Guzman
doaj   +1 more source

Parallel Geometric Hashing Algorithm For Protein Tertiary Structure. [PDF]

, 2007
The amount of protein structure has become very huge nowadays, which has led to the need for improving algorithms to cope with this exponential increase.
Jaber, Khalid, Abdullah, Rosni, Othman, Fazilah   +2 more
core   +1 more source