Results 141 to 150 of about 798,978 (348)

Geology of the Tehachapi Mountains, California [PDF]

, 1954
The San Joaquin-Sacramento Valley, also known as the Great Valley of California, separates the Coast Ranges on the west from the Sierra Nevada on the east. The southern part of this major physiographic and structural province is about 50 miles in average
Buwalda, John P.
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

To split or not to split: CASP15 targets and their processing into tertiary structure evaluation units. [PDF]

Proteins, 2023
Kryshtafovych A, Rigden DJ.
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Exploring effects of gut microbiota on tertiary lymphoid structure formation for tumor immunotherapy

Frontiers in Immunology
Anti-tumor immunity, including innate and adaptive immunity is critical in inhibiting tumorigenesis and development of tumor. The adaptive immunity needs specific lymph organs such as tertiary lymphoid structures (TLSs), which are highly correlated with ...
Yuqing Liu, Fan Li, Juanjuan Wang, Rongcun Yang, Rongcun Yang, Rongcun Yang   +5 more
doaj   +1 more source

APOBEC3A Catalytic Inactivity Mutation Induces Tertiary Structure Destabilization. [PDF]

ACS Med Chem Lett, 2023
Jones KFM, Shehata M, Carpenter MA, Amaro RE, Harki DA.   +4 more
europepmc   +1 more source

Tertiary activities and informality: quantitative importance and interconnections within the economy in Brazil [PDF]

This paper studies the importance of the Tertiary sector and the informal sector for the Brazilian economy, making an interconnection between them and with them and the rest of the economy and the formal sector.
Azzoni, Carlos Roberto, Guilhoto, Joaquim José Martins   +1 more
core   +1 more source

Supplementary Figure 1 from Dendritic Cells in Tumor-Associated Tertiary Lymphoid Structures Signal a Th1 Cytotoxic Immune Contexture and License the Positive Prognostic Value of Infiltrating CD8⁺ T Cells [PDF]

, 2023
Jérémy Goc, Claire Germain, Thi Kim Duy Vo-Bourgais, Audrey Lupo, Christophe Klein, Samantha Knockaert, Luc de Chaisemartin, Hanane Ouakrim, Étienne Becht, Marco Alifano, Pierre Validire, Romain Remark, Scott A. Hammond, Isabelle Cremer, Diane Damotte, Wolf H. Fridman, Catherine Sautès‐Fridman, Marie‐Caroline Dieu‐Nosjean   +17 more
openalex   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Perception of the content, structure and delivery of antenatal health education received by pregnant women in Ibadan, Nigeria: a cross-sectional study

Discover Public Health
Introduction Investigating the structure of antenatal health education (AHE) received by women is crucial for improving maternal and child health outcomes.
Titilope Adenike Oluranti, Victoria Bolanle Brown, Aanuoluwapo Adeyimika Afolabi, Olufemi Idowu Oluranti, Abimbola Oyeninhun Oluwatosin   +4 more
doaj   +1 more source