Results 131 to 140 of about 291,656 (309)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Simultaneous prediction of RNA secondary structure and helix coaxial stacking

BMC Genomics, 2012
Background RNA secondary structure plays a scaffolding role for RNA tertiary conformation. Accurate secondary structure prediction can not only identify double-stranded helices and single stranded-loops but also help provide information for potential ...
Shareghi Pooya, Wang Yingfeng, Malmberg Russell, Cai Liming   +3 more
doaj   +1 more source

Tertiary activities and informality: quantitative importance and interconnections within the economy in Brazil

This paper studies the importance of the Tertiary sector and the informal sector for the Brazilian economy, making an interconnection between them and with them and the rest of the economy and the formal sector.
Guilhoto, Joaquim José Martins, Azzoni, Carlos Roberto   +1 more
core  

On the significance of an RNA tertiary structure prediction

, 2010
Tertiary structure prediction is important for understanding structure–function relationships for RNAs whose structures are unknown and for characterizing RNA states recalcitrant to direct analysis. However, it is unknown what root-mean-square deviation (
F. Ding, N. V. Dokholyan, Hajdin, C. E., Weeks, K. M., C. E. Hajdin, K. M. Weeks, Dokholyan, N. V., Ding, F.   +7 more
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Improving AlphaFold2-based protein tertiary structure prediction with MULTICOM in CASP15. [PDF]

Commun Chem, 2023
Liu J, Guo Z, Wu T, Roy RS, Chen C, Cheng J.   +5 more
europepmc   +1 more source

L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy

, 2006
Ribosomal proteins are assumed to stabilize specific RNA structures and promote compact folding of the large rRNA. The conformational dynamics of the protein between the bound and unbound state play an important role in the binding process.
Wöhnert, Jens, Hendrik R. A. Jonker, Harald Schwalbe, Ilin, Serge, S. Kaspar Grimm, Grimm, Steffen Kaspar, Jens Wöhnert, Jonker, Hendrik R. A., Schwalbe, Harald (Prof. Dr.), Serge Ilin   +9 more
core   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

To split or not to split: CASP15 targets and their processing into tertiary structure evaluation units. [PDF]

Proteins, 2023
Kryshtafovych A, Rigden DJ.
europepmc   +1 more source

Enhanced Honey Bees Colony Algorithms For Protein Tertiary Structure Prediction [PDF]

, 2011
There is no doubt about the role that protein plays in the biological processes inside the human body. Proteins are able to perform their biological functions when they fold into their tertiary structure.
Bahamish, Hesham Awadh Abdallah
core