Results 11 to 20 of about 258,881 (309)
A triphosphate tunnel metalloenzyme from pear (PbrTTM1) moonlights as an adenylate cyclase
Frontiers in Plant Science, 2023 Adenylyl cyclase (AC) is the vital enzyme for generating 3′,5′-cyclic adenosine monophosphate, an important signaling molecule with profound nutritional and medicinal values.
Ye Yuan +14 more
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Characterization of transcription profile and structural properties of avian NK-lysin
Poultry Science, 2020 This study aimed to determine the transcription profile of NK-lysin gene in native chickens. Moreover, it was targeted toward determining the primary, three-dimensional, and molecular dynamic structures of NK-lysin and granulysin peptides to understand ...
Maged M. Mahmoud, Haitham A. Yacoub
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Two triphosphate tunnel metalloenzymes from apple exhibit adenylyl cyclase activity
Frontiers in Plant Science, 2022 Adenylyl cyclase (AC) is the key catalytic enzyme for the synthesis of 3′,5′-cyclic adenosine monophosphate. Various ACs have been identified in microorganisms and mammals, but studies on plant ACs are still limited.
Ye Yuan +13 more
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Reducing Ensembles of Protein Tertiary Structures Generated De Novo via Clustering
Molecules, 2020 Controlling the quality of tertiary structures computed for a protein molecule remains a central challenge in de-novo protein structure prediction. The rule of thumb is to generate as many structures as can be afforded, effectively acknowledging that ...
Ahmed Bin Zaman +3 more
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A novel mutation in the cathepsin C (CTSC) gene in Iranian family with Papillon‐Lefevre syndrome
Clinical and Experimental Dental Research, 2021 Objectives In this study, we analyzed the whole exomes of CTSC gene in a family with history of PLS. Materials and methods Genomic DNA was extracted from peripheral blood and genotype analysis was performed.
Mahmoud Ghanei +4 more
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Molecular Therapy: Nucleic Acids, 2021 Aptamers are short, single-stranded DNA or RNA oligonucleotide molecules that function as synthetic analogs of antibodies and bind to a target molecule with high specificity.
Dmitry Morozov +18 more
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Generative Adversarial Learning of Protein Tertiary Structures
Molecules, 2021 Protein molecules are inherently dynamic and modulate their interactions with different molecular partners by accessing different tertiary structures under physiological conditions. Elucidating such structures remains challenging.
Taseef Rahman +3 more
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Plants, 2016 The two major storage proteins identified in Brassica napus (canola) were isolated and studied for their molecular composition, structural characteristics and the responses of structural features to the changes in pH and temperature.
Suneru P. Perera +2 more
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Journal of Lipid Research, 2010 Apolipoprotein A-I (apoA-I) Nichinan, a naturally occurring variant with ΔE235 in the C terminus, is associated with low plasma HDL levels. Here, we investigated the tertiary structure, lipid-binding properties, and ability to induce cellular cholesterol
Momoe Kono +9 more
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Biological Significance of the Genomic Variation and Structural Dynamics of SARS-CoV-2 B.1.617
Frontiers in Microbiology, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have been emerging and circulating globally since the start of the COVID-19 pandemic, of which B.1.617 lineage that was first reported in India at the end of 2020, soon became ...
Lin-qian Fan +7 more
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