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Computing tertiary structures of proteins
Journal of Protein Chemistry, 1990Using only data on sequence, a method of computing a low-resolution tertiary structure of a protein is described. The steps are: (a) Estimate the distances of individual residues from the centroid of the molecule, using data on hydrophobicity and additional geometrical constraints. (b) Using these distances, construct a two-valued matrix whose elements,
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1989
The polypeptide chain of globular protein is linear, but the three-dimensional of tertiary structure is quite contorted. This was apparent from the first crystallographic determination of the structure of a protein by Kendrew et al. (1960). The contortion arises because of the need to satisfy a multitude of conflicting interactions: the hydrogen ...
Fred E. Cohen, Irwin D. Kuntz
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The polypeptide chain of globular protein is linear, but the three-dimensional of tertiary structure is quite contorted. This was apparent from the first crystallographic determination of the structure of a protein by Kendrew et al. (1960). The contortion arises because of the need to satisfy a multitude of conflicting interactions: the hydrogen ...
Fred E. Cohen, Irwin D. Kuntz
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Maturation of Tertiary Lymphoid Structures
Tertiary lymphoid structures (TLS) are organized collections of B and T lymphocytes that arise in nonlymphoid tissue in response to chronic, unresolved inflammation. TLS have structural and functional similarities to germinal centers found in lymph nodes and are believed to support the establishment of lymph node-like adaptive immune responses at localDaniel H, Shu, Dimitrios N, Sidiropoulos
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Secondary and Tertiary Structure
1988The bond between the carbon atom of the carbonyl group and the amide nitrogen has partial double bond character that can be attributed to resonance: Open image in new window Accordingly, the carbonyl carbon and oxygen atoms, the amide nitrogen and hydrogen and the two adjacent α-carbon atoms He approximately in the same plane.
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[Tertiary structure of histones].
TSitologiia i genetika, 1976Optical absorption and fluorescence of histones F2a and F2b were studied. An increase in pH and ionic strength induced the structure change in these histones fractions. The hydrofobic sites are formed in protein molecules and this leads to an intensification of histone-histone interactions.
S N, Khrapunov +2 more
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2003
Experimental methods such as nuclear magnetic resonance spectroscopy or x-ray diffraction analysis are widely used in order to determine tertiary pro- tein structures. But the rate at which protein structures can be determined by experimental techniques is much lower than the rate at which new genes are identified by the various genome projects ...
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Experimental methods such as nuclear magnetic resonance spectroscopy or x-ray diffraction analysis are widely used in order to determine tertiary pro- tein structures. But the rate at which protein structures can be determined by experimental techniques is much lower than the rate at which new genes are identified by the various genome projects ...
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Tertiary Structure of Proteins
2010In Chapter 4, we gave a brief introduction to proteins. The structures of a very large number of proteins have been determined and it is possible to ask fundamental questions: Given the primary sequence, what is tertiary structure? How does the protein fold into the final structure? This “folding problem” has attracted a great deal of attention, and it
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The prognostic value of the tertiary lymphoid structure in gastrointestinal cancers
Frontiers in Immunology, 2023Aoyang Yu, Kaile Zhang, Menghan Cao
exaly
The tertiary structure of clostridiopeptidase B
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1969W M, Mitchell, J J, Schmidt
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