Results 51 to 60 of about 2,910 (186)

The Avian Encephalomyelitis Virus (AEV) 5’ Untranslated Region Contains an IRES with Similarity to the Hepatitis C Virus IRES [PDF]

Iranian Journal of Public Health, 2005
Cap-independent internal initiation of protein synthesis has been shown to occur on a number of viral and cellular mRNAs. Initiation of protein synthesis is directed by an internal ribosome entry site (IRES) element within the 5’ untranslated region (UTR)
M Bakhshesh, L Roberts, G J Belsham
doaj   +2 more sources

Death receptor-based enrichment of Cas9-expressing cells [PDF]

, 2016
Background: The CRISPR/Cas9 genome editing system has greatly facilitated and expanded our capacity to engineer mammalian genomes, including targeted gene knock-outs. However, the phenotyping of the knock-out effect requires a high DNA editing efficiency.
Aschenbrenner, S., Beaudouin, J., Eils, Roland, Grimm, Dirk, Große, Stefanie, Liesche, Clarissa, Venkatraman, L.   +6 more
core   +1 more source

Congenital Microphthalmic Syndrome in a Swine

Case Reports in Veterinary Medicine, 2018
A 17-week-old crossbred finishing pig was presented for lameness of approximately one week. Clinical evaluation, including ophthalmologic examination, revealed ataxia, partial flaccid paresis of the pelvic limbs, skin lesions at feet and claws, and ...
Radka Andrysikova, Titus Sydler, Dolf Kümmerlen, Wolfgang Pendl, Robert Graage, Romana Moutelikova, Jana Prodelalova, Katrin Voelter   +7 more
doaj   +1 more source

Epidemics to eradication: the modern history of poliomyelitis [PDF]

, 2007
Poliomyelitis has afflicted humankind since antiquity, and for nearly a century now, we have known the causative agent, poliovirus. This pathogen is an enterovirus that in recent history has been the source of a great deal of human suffering.
Nidia H De Jesus
core   +2 more sources

A novel class of microRNA-recognition elements that function only within open reading frames. [PDF]

, 2018
MicroRNAs (miRNAs) are well known to target 3' untranslated regions (3' UTRs) in mRNAs, thereby silencing gene expression at the post-transcriptional level.
A Aizer, A Helwak, A Jakymiw, A Lal, AE Pasquinelli, AJ Giraldez, Alexander Dobin, AM Duursma, AR Buskirk, AR Quinlan, B Langmead, Bing Zhou, CJ Decker, CJ Shoemaker, CJ Woolstenhulme, CP Petersen, Dehe Wang, DP Bartel, DT Humphreys, E Huntzinger, EL Nostrand Van, GB Loeb, Guangqiao Liu, H Guo, HA Meijer, HO Iwakawa, I Behm-Ansmant, I Elcheva, J Hausser, J Liu, J Liu, JH Kim, Jie Zhou, JJ Forman, JP Broughton, K Seggerson, KA O’Donnell, Kai Zhang, L Wu, Ligang Wu, M Hafner, M Kouwenhove van, M Rehmsmeier, MD Robinson, MK Doma, ML Donnelly, N Rajewsky, NT Schirle, PA Maroney, Qian Zhao, R Ishimura, R Ishimura, R Parker, Ran Cao, RS Pillai, S Bagga, S Djuranovic, S Grosswendt, S Gu, S Jonas, S Nottrott, S Takagi, SN Bhattacharyya, SW Chi, SW Eichhorn, Timothy Nilsen, TT Tat, V Presnyak, W Filipowicz, Wen Ruan, X Adiconis, Xiang-Dong Fu, Xiaorong Zhang, Y Ishigaki, Y Liao, Y Tay, Y Wang, Y Xue, Y Zhao, Ya Zhao, Yan Qin, Yu Zhou, Yuanchao Xue, Z Cai, Zhiqiang Cai, Zonggui Chen   +85 more
core   +2 more sources

SPLICEIT Fluorescent Sensor for Integrating Dopamine Release with Cellular Resolution

Angewandte Chemie, Volume 137, Issue 33, August 11, 2025.
“Single‐chain protein‐based ligand indication through a chimerically‐engineered integrator tool” (SPLICEIT) is a G‐protein coupled receptor‐based sensor design that leaves a permanent fluorescent mark. We show dopamine detection in primary cultured neurons with a fourfold signal increase normalized to an mCherry (mCh) marker.
Steven M. Havens, Brian Georgis, Jian Weng, Jessi Rodriguez, Hannah Rivett, Shadan Alrawi, Peng Li, Wenjing Wang   +7 more
wiley   +2 more sources

Protease-Independent Production of Poliovirus Virus-like Particles in Pichia pastoris: Implications for Efficient Vaccine Development and Insights into Capsid Assembly

Microbiology Spectrum, 2023
The production of enterovirus virus-like particles (VLPs) that lack the viral genome have great potential as vaccines for a number of diseases, such as poliomyelitis and hand, foot, and mouth disease.
Lee Sherry, Jessica J. Swanson, Keith Grehan, Huijun Xu, Mai Uchida, Ian M. Jones, Nicola J. Stonehouse, David J. Rowlands   +7 more
doaj   +1 more source

Developing a disease prevention strategy in the Caribbean: the importance of assessing animal health-related risks at regional level [PDF]

, 2011
En 2009, le réseau CaribVET a réalisé une enquête au sein des Services vétérinaires des pays et territoires de la Caraïbe afin d'évaluer les perceptions associées à l'évaluation du risque et d'identifier les principales maladies exotiques d'intérêt pour ...
Bournez, Laure, Delgado, Amy, Depaz, M., Frias Lepoureau, Maria Teresa, Gomez, L., Gongora, Victor, Guitian, Javier, Herbert-Hackshaw, K., Lazarus, C., Lefrançois, Thierry, Lopez, J.F., Parris Aaron, M., Percedo Abreu, M.I., Petit Sinturel, Marion, Phanord, Siméon, Pradel, Jennifer, Sanford, Bryan, Titus, S., Trotman, Mark   +18 more
core   +1 more source

Detection and molecular characterization of porcine enterovirus G15 and teschovirus from India

Pathogens and Disease, 2020
ABSTRACT Porcine enterovirus G (EV-G) and teschovirus (PTV) generally cause asymptomatic infections. Although both viruses have been reported from various countries, they are rarely detected from India. To detect these viruses in Western India, fecal samples (n = 26) of diarrheic piglets aged below three months from private pig farms ...
Pradeep Mahadev Sawant, Nitin Atre, Abhijeet Kulkarni, Varanasi Gopalkrishna   +3 more
openaire   +2 more sources

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

Angewandte Chemie International Edition, EarlyView.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source