Detection of Porcine Teschovirus and Enterovirus Type II by Reverse Transcription–Polymerase Chain Reaction [PDF]
Journal of Veterinary Diagnostic Investigation, 2002 Porcine enteroviruses (PEVs) have been recognized as the causative agents of various clinical manifestations such as fertility disorders, neurological defects, and dermal lesions in pigs. Currently, the diagnosis of PEV infection is carried out by virus isolation, which although useful, is labor- and time-intensive. The present investigation describes
Joseph M, Palmquist +4 more
openaire +2 more sources
Advanced Science, Volume 12, Issue 39, October 20, 2025.A next‐generation cytosine base editor (zTadCBE) and other variants are developed by combining the high‐efficiency (TadCBEa) and low‐indel (TadCBEMax) architectures, followed by the introduction of zebrafish‐optimized mutations (V82S, Q154R) in the TadA domain.
Wei Qin +7 more
wiley +1 more source
Virology Journal, 2018 Background Emergence and re-emergence of porcine epidemic diarrhea virus (PEDV) in North America, Asia and Europe has caused severe economic loss to the global swine industry.
Qi Chen +9 more
doaj +1 more source
Risk analysis tool developed to assist with decision-making on prevention of swine diseases. Application to Porcine Epidemic Diarrhea in Caribbean countries. [P029] [PDF]
, 2015 Purpose Classical Swine Fever (CSF) and Teschovirus Encephalomyelitis (TE) have been identified as priority diseases for the Caribbean because of their sanitary, economic and social repercussions in affected countries, together with their high diffusion ...
Calvo, Francisco +9 more
core
Multiple Sclerosis Gene Therapy Using Recombinant Viral Vectors: Overexpression of IL-4, IL-10 and Leukemia Inhibitory Factor in Wharton's Jelly Stem Cells in The EAE Mice Model [PDF]
, 2017 Objective: Immunotherapy and gene therapy play important roles in modern medicine. The aim of this study is to evaluate the overexpression of interleukin-4 (IL-4), IL-10 and leukemia inhibitory factor (LIF) in Wharton's jelly stem cells (WJSCs) in the ...
Abdolhosseinzadeh, Baharak. +7 more
core +1 more source
Antigenic and immunogenic properties of industrial strains of Porcine Teschovirus
Agroecological journal, 2015 90 samples of brain and spinal cord from dead or forced slaughtered pigs with clinical signs Teschen disease were selected and investigated. Of the 28 samples taken we selected isolates viruses which have morphological, physical, chemical, biological, molecular-genetic and antigenic properties attributed to species Porcine teschovirus (PTV) genus ...
openaire +3 more sources
Influence of brain-derived neurotrophic factor on pathfinding of dentate granule cell axons, the hippocampal mossy fibers [PDF]
, 2009 Mossy fibers, the dentate granule cell axons, are generated throughout an animal's lifetime. Mossy fiber paths and synapses are primarily restricted to the stratum lucidum within the CA3 region.
Makoto Tamura +6 more
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Animal Models and Experimental Medicine, Volume 8, Issue 8, Page 1468-1479, August 2025.We generated two neuron‐specific Cre rat lines, Thy1‐Cre and NeuN‐Cre, using CRISPR/Cas9‐mediated targeted insertion. Both lines were validated for high neural specificity by crossing them with a Cre reporter rat. When bred with an ND1 conditional knockout rat, the two Cre lines produced distinct phenotypic outcomes. These rat lines have been deposited
Keru Li +15 more
wiley +1 more source
The complete genome of klassevirus – a novel picornavirus in pediatric stool
Virology Journal, 2009 Background Diarrhea kills 2 million children worldwide each year, yet an etiological agent is not found in approximately 30–50% of cases. Picornaviral genera such as enterovirus, kobuvirus, cosavirus, parechovirus, hepatovirus, teschovirus, and ...
Ganem Donald +6 more
doaj +1 more source
Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis [PDF]
, 2017 Genetic alterations conferring resistance to the effects of chemical inhibitors are valuable tools for validating on-target effects in cells. Unfortunately, for many therapeutic targets such alleles are not available.
Arai, E. +7 more
core +1 more source