Results 61 to 70 of about 2,879 (174)

Immunohistochemical Distribution of Viral Antigens in Pigs Naturally Infected with Porcine Teschovirus

open access: yesJournal of Veterinary Medical Science, 2008
A distribution of porcine teschovirus (PTV) antigens in pigs naturally infected with PTV is presented using the method of immunohistochemical examination. In the nervous system, PTV antigens were found in the cytoplasm of neuronal cells and glial cells distributed in the spinal ventral horn and brain stem, and also in the cytoplasm of ganglion cells in
Manabu, Yamada   +8 more
openaire   +3 more sources

Prediction of Potential Epitopes for Peptide Vaccine Formulation Against Teschovirus A Using Immunoinformatics [PDF]

open access: yesInternational Journal of Peptide Research and Therapeutics, 2019
Teschovirus A belongs to the family Picornaviridae and is a causal agent of the disease Teschovirus encephalomyelitis and other infections that remain asymptomatic. The present study was performed to design epitope-based peptide vaccine against Teschovirus A by identifying the potential T cell and B-cell epitopes from capsid proteins (VP1, VP3 and VP2)
Barman, Antara   +2 more
openaire   +2 more sources

A Comprehensive Multiomics Approach Illuminates the Biosynthetic Mechanism of Scoparone in Artemisia capillaris

open access: yesPlant Biotechnology Journal, Volume 24, Issue 1, Page 346-360, January 2026.
ABSTRACT Artemisia capillaris, a traditional Chinese medicinal plant, has displayed favourable effects in the treatment of jaundice, inflammation of the liver and cholecystitis for thousands of years. However, the biosynthesis of scoparone, the major active component in A. capillaris, remains unclear.
Fuyou Guo   +15 more
wiley   +1 more source

Developing a disease prevention strategy in the Caribbean: the importance of assessing animal health-related risks at regional level [PDF]

open access: yes, 2011
En 2009, le réseau CaribVET a réalisé une enquête au sein des Services vétérinaires des pays et territoires de la Caraïbe afin d'évaluer les perceptions associées à l'évaluation du risque et d'identifier les principales maladies exotiques d'intérêt pour ...
Bournez, Laure   +18 more
core   +1 more source

Rationally Designed TadA‐Derived Cytosine Editors Enable Context‐Independent Zebrafish Genome Editing

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
A next‐generation cytosine base editor (zTadCBE) and other variants are developed by combining the high‐efficiency (TadCBEa) and low‐indel (TadCBEMax) architectures, followed by the introduction of zebrafish‐optimized mutations (V82S, Q154R) in the TadA domain.
Wei Qin   +7 more
wiley   +1 more source

A viral metagenomic survey identifies known and novel mammalian viruses in bats from Saudi Arabia.

open access: yesPLoS ONE, 2019
Bats are implicated as natural reservoirs for a wide range of zoonotic viruses including SARS and MERS coronaviruses, Ebola, Marburg, Nipah, Hendra, Rabies and other lyssaviruses.
Nischay Mishra   +15 more
doaj   +1 more source

Epidemics to eradication: the modern history of poliomyelitis [PDF]

open access: yes, 2007
Poliomyelitis has afflicted humankind since antiquity, and for nearly a century now, we have known the causative agent, poliovirus. This pathogen is an enterovirus that in recent history has been the source of a great deal of human suffering.
Nidia H De Jesus
core   +2 more sources

Metagenomic analysis of the RNA fraction of the fecal virome indicates high diversity in pigs infected by porcine endemic diarrhea virus in the United States

open access: yesVirology Journal, 2018
Background Emergence and re-emergence of porcine epidemic diarrhea virus (PEDV) in North America, Asia and Europe has caused severe economic loss to the global swine industry.
Qi Chen   +9 more
doaj   +1 more source

Generation of a TALEN-mediated, p63 knock-in in human induced pluripotent stem cells [PDF]

open access: yes, 2017
The expression of p63 in surface ectodermal cells during development of the cornea, skin, oral mucosa and olfactory placodes is integral to the process of cellular self-renewal and the maintenance of the epithelial stem cell status.
Hayashi, R.   +3 more
core   +3 more sources

Comparative analysis of two newly established Cre rat lines, NeuN‐Cre and Thy1‐Cre, for neurological research

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 8, Page 1468-1479, August 2025.
We generated two neuron‐specific Cre rat lines, Thy1‐Cre and NeuN‐Cre, using CRISPR/Cas9‐mediated targeted insertion. Both lines were validated for high neural specificity by crossing them with a Cre reporter rat. When bred with an ND1 conditional knockout rat, the two Cre lines produced distinct phenotypic outcomes. These rat lines have been deposited
Keru Li   +15 more
wiley   +1 more source

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