Results 101 to 110 of about 79,305 (292)

Development and validation of an explainable machine learning model for mortality prediction in ICU patients with lung cancer

Frontiers in Cell and Developmental Biology
Background and ObjectiveLung cancer is the leading cause of cancer-related death worldwide, with a particularly high mortality risk among patients admitted to the intensive care unit (ICU).
Jinhong Xia, Jingyuan Zhang, Siyu Zhang, Cheng Liu, Zhiyu Liu, Yuxi Zhao, Huaran Zhang, Min Shen   +7 more
doaj   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Analysis of different IDS-based machine learning models for secure data transmission in IoT networks

Open Computer Science
The Internet of Things (IoT) encompasses a network of interconnected devices that collect, analyze, and exchange vast amounts of data. However, this connectivity creates opportunities for various types of cyberattacks, making IoT systems vulnerable and ...
Gladić Dejana, Petrovački Jelena, Sladojević Srdan, Arsenović Marko, Ristić Sonja   +4 more
doaj   +1 more source

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source

Propensity Score Adjustment in Measurement Invariance [PDF]

, 2017
Measurement invariance testing is prerequisite if meaningful comparisons of latent construct across groups are important to the study in social science.
Cao, Qian
core  

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Gold Price Forecasting using Time Series Modeling on a Web Platform

Journal of Innovation Information Technology and Application
Gold is one of the most favored investment instruments due to its stability and its ability to preserve value against inflation. However, its price movements are volatile and influenced by various global economic factors, currency exchange rates, and ...
Dwi Ratna Puspita Sari, Sirli Fahriah, Kurnianingsih, Santi Purwaningrum   +3 more
doaj   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source

Relationship Between Systematic Risk and ESG in Brazil

Revista Catarinense da Ciência Contábil
Sustainability has become a central concern for both academia and financial markets, particularly regarding the potential of Environmental, Social, and Governance (ESG) practices to mitigate corporate risk.
Pedro Henrique de Oliveira Santos, Marcio Marcelo Belli, Luiz Eduardo Gaio   +2 more
doaj   +1 more source

Test-Based Accountability and Student Achievement: An Investigation of Differential Performance on NAEP and State Assessments [PDF]

This paper explores the phenomenon referred to as test score inflation, which occurs when achievement gains on "high-stakes" exams outpace improvements on "low-stakes" tests.
Brian A. Jacob
core