Results 41 to 50 of about 8,095,618 (291)

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay   +13 more
wiley   +1 more source

Further Comment on "'Lake Woebegone,' Twenty Years Later"

open access: yesNonpartisan Education Review, 2006
no ...
Richard P. Phelps
doaj  

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera   +20 more
wiley   +1 more source

“Lake Woebegone,” Twenty Years Later

open access: yesNonpartisan Education Review, 2006
Twenty years ago, John Cannell developed data on test scores that became known as the “Lake Woebegone effect.” This commentary describes that experience.
John Jacob Cannell, M.D.
doaj  

Score Tests for Semiparametric Zero-inflated Poisson Models

open access: yesInternational Journal of Statistics and Probability, 2012
Count data sets often produce many zeros. It is sometimes potentially questionable to use a linear predictor to model the effect of a continuous covariate of interest in zero-inflated count data. To relax the restriction, Li (2011) proposed a semiparametric zero-inflated Poisson (ZIP) regression model by using fixed-knot cubic $basis$ splines or $B ...
openaire   +2 more sources

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

Item - Test Alternate Title

open access: yes
Item - Test Description ...
Item - Test Creator 1   +2 more
core   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno   +19 more
wiley   +1 more source

Comments on "'Lake Woebegone,' Twenty Years Later"

open access: yesNonpartisan Education Review, 2006
J. J. Cannell’s article on the so-called “Lake Woebegone” effect for K-12 educational testing systems is mostly an historical account of technical issues and policy considerations that led in part to development of new types of test instruments for K-12 ...
D. J. McRae, Ph.D.
doaj  

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram   +3 more
wiley   +1 more source

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