Results 131 to 140 of about 5,712,508 (248)

Molecular Tumor Boards in Malignant Melanoma: Uncovering Challenges and Opportunities in a Bicenter Retrospective Analysis in Germany

International Journal of Cancer, Volume 159, Issue 9, Page 2290-2299, 1 November 2026.
Molecular tumor boards (MTB), interdisciplinary teams that use tumor genomic data to guide personalized treatment decisions, have emerged as a promising strategy in melanoma care, although their real‐world clinical impact remains uncertain. This retrospective study evaluated advanced melanoma patients to assess molecularly guided treatment ...
Glenn Geidel, Theresa Lowinus, Patrick Metzger, Rebecca Czurda, Vincent Schipperges, Ulrike Paul, Alessandra Rünger, Julian Kött, Isabel Heidrich, Saskia Lehr, Julia Kühn, Heiko Becker, Cornelius Miething, Martin Werner, Silke Laßmann, Justus Duyster, Tilman Brummer, Ronald Simon, Winfried Alsdorf, Maximilian Christopeit, Carsten Bokemeyer, Kilian Eyerich, Stefan W. Schneider, David Rafei, Melanie Börries, Frank Meiss, Christoffer Gebhardt   +26 more
wiley   +1 more source

Testisin, a new human serine proteinase expressed by premeiotic testicular germ cells and lost in testicular germ cell tumors [PDF]

, 1999
We have cloned and characterized a cDNA encoding a new human serine proteinase, testisin, that is abundantly expressed only in the testis and is lost in testicular tumors.
Antalis, T., Stuttgen, M., Loveland, K. A. L., Dickinson, Joanne L., Sutherland, Grant R., Nicol, D., Eyre, H., Normyle, J., Hooper, John D., Lakoski-Loveland, Kate A., Douglas, Meaghan L., Eyre, Helen J., Hooper, J. D., Stuttgen, Melanie A., Dickinson, J., Sutherland, G., Dickinson, J. L., Eyre, H. J., Hooper, J., Normyle, John F., Scarman, A., Antalis, T. M., Nicol, David L., Scarman, A. L., Stuttgen, M. A., Douglas, M., Loveland, K., Douglas, M. L., Antalis, Toni M., Normyle, J. F., Sutherland, G. R., Scarman, Anthony L., Nicol, D. L.   +32 more
core  

Diagnosis, treatment, and long-term follow-up of a 13-year-old boy with a testicular mixed germ cell tumor (yolk sac tumor and embryonal carcinoma): a case report and literature review

Frontiers in Pediatrics
Testicular germ cell tumors (TGCTs) are rare in children under 15 years of age. We report the first documented case of a mixed yolk sac tumor and embryonal carcinoma in the left testis of a 13-year-old boy in the early stages of puberty (12–14 years ...
Jing Yang, Jianjun Lai, Shiping Zheng, Huanmei Tang   +3 more
doaj   +1 more source

Rapidly Progressive Metastatic Sertoli Cell Tumor Associated With an Adenomatous Polyposis Coli Mutation: A Case Report and Literature Review

IJU Case Reports, Volume 9, Issue 6, November 2026.
ABSTRACT Introduction Sertoli cell tumors are rare testicular sex cord‐stromal tumors, and clinically malignant behavior is uncommon. We report a rapidly progressive metastatic Sertoli cell tumor associated with an APC mutation. Case Presentation A 27‐year‐old man with familial adenomatous polyposis (FAP) presented with painless right scrotal ...
Kotaro Obayashi, Mika Terasaki, Hiroya Hasegawa, Hikaru Mikami, Masato Yanagi, Hayato Takeda, Yuki Endo, Yuka Toyama, Ryuji Ohashi, Jun Akatsuka   +9 more
wiley   +1 more source

Trends in testicular germ cell cancer incidence in Australia

, 2008
Objective: Although increasing incidence of testicular\ud germ cell cancer has been reported in many developed\ud nations, national estimates for Australia, with histological\ud differentiation, are not currently available.-----\ud Methods: Using data ...
Baade, Peter D., Carriere, Philippe, Fritschi, Lin, Carrière, P., Baade, Peter, Fritschi, L.   +5 more
core   +1 more source

Protective Effects of Lactobacillus‐Derived Probiotics and Postbiotics on Renal and Reproductive Function in Escherichia coli–Infected Rats

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
A Lactobacillus‐derived probiotic and postbiotic mixture alleviates E. coli–induced renal and reproductive dysfunction by modulating oxidative stress, inflammatory responses, and apoptosis, leading to improved tissue integrity and sperm quality. ABSTRACT Background Escherichia coli infections of the genitourinary tract are a major cause of renal and ...
Saeid Sedghi, Zahra Keshtmand, Saba Hosseini   +2 more
wiley   +1 more source

Sociodemographic Factors Associated With Later Stage at Diagnosis of Pediatric Germ Cell Tumors: A Report From Children's Oncology Group Registries ACCRN07 and APEC14B1

Pediatric Blood &Cancer, Volume 73, Issue 10, October 2026.
ABSTRACT Background Germ cell tumors (GCTs) often arise in the ovaries and testes (extracranial) but can also develop in the brain (intracranial). We examined the relationship of individual, family, and community‐level socioeconomic status (SES) with stage of disease at diagnosis in a cohort of pediatric patients with GCT from Children's Oncology Group
Heydon K. Kaddas, Judy Y. Ou, Todd Alonzo, Logan G. Spector, Negar Fallahazad, Emily Owens, Anne C. Kirchhoff, Adam L. Green   +7 more
wiley   +1 more source

Does age affect the prognosis of patients with testicular germ cell tumor?

, 2007
Introduction: In this study, the effect of age on the prognosis of testicular germ cell tumors in patients over 40 was investigated. Materials and Methods: Ninety- three patients with testicular germ cell tumor who were 40 years old and over were ...
Tasar, Celik, Ergen, Ali, Ozen, Haluk, Akdogan, Bulent, Dogan, Hasan Serkan, Inci, Kubilay   +5 more
core   +1 more source

Cancer Risk in Marfan Syndrome: A Swedish Population‐Based Cohort Study

International Journal of Cancer, Volume 159, Issue 7, Page 1707-1714, 1 October 2026.
The cancer risk in Marfan syndrome, an autosomal dominant connective tissue disorder, largely remains to be explored. In this population‐based matched cohort study of 1544 Swedish patients, the overall cancer risk in adults with Marfan syndrome showed no significant increase, except for the risk of endocrine tumours with a nearly threefold increase ...
Ida Nordgren, Anna Skarin Nordenvall, Alexandra Wachtmeister, Fulya Taylan, Yunxia Lu, Christina Norrby, Anna Lindstrand, Giedre Grigelioniene, Giorgio Tettamanti   +8 more
wiley   +1 more source

Adult Type Granulosa Cell Tumor of the Testis: Case Report and Review of the Literature

Eurasian Journal of Medicine, 2019
Testicular granulosa cell tumors are extremely rare in adults. We report a case of a testicular germ cell tumor (GCT) in a 21-year-old man. The tumor was treated successfully with radical orchiectomy, and follow-up computed tomography revealed no ...
Zafer Kucukodaci, Muzaffer Keles, Turgut Yapanoğlu, Bilal Firat Alp, Yilmaz Aksoy, İsa Özbey   +5 more
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