Results 121 to 130 of about 5,712,508 (248)

A Noncanonical Protein Degradation Pathway That Regulates Germ Cell Maintenance

open access: yesCell Proliferation, EarlyView.
SENP8 regulates a non‐canonical NEDD8‐dependent pathway to stabilize STAT1, promote CCL2/CCL5 transcription, and maintain germ cell proliferation and migration.
Meng Liu   +11 more
wiley   +1 more source

A case of bilateral testicular germ cell tumor [PDF]

open access: yes, 1989
A case of bilateral successive tumor of germ cell origin is reported. A 29-year-old man visited our clinic with a complaint of swelling of right scrotal contents 18 months after initial left orchiectomy for a seminoma. The right orchiectomy was performed
川村, 寿一   +6 more
core  

Primary lung chordoma: a case report

open access: yesDiagnostic Pathology
Background Chordoma, a rare malignant tumor arising from notochordal tissue, usually occurs along the spinal axis. Only a few published reports of primary lung chordomas exist.
Naoko Shigeta   +7 more
doaj   +1 more source

Wt1 Is Required for the Regression of Müllerian Ducts in Male Mice by Inducing Wif1 and Osx Expression

open access: yesCell Proliferation, EarlyView.
Wt1 expressed in the MD mesenchyme promotes MD regression by inducing Wif1 and Osx transcription. In male mice, mesenchyme‐specific inactivation of Wt1 results in MD retention. ABSTRACT In mammals, Müllerian ducts (MDs) are the precursors of the female reproductive tract which regress in males during embryonic development.
Min Chen   +12 more
wiley   +1 more source

CASE REPORT: Cytologic Diagnosis of Metastatic Seminoma in Neck Nodes as Initial Presentation [PDF]

open access: yesJournal of Krishna Institute of Medical Sciences University, 2012
Background: Testicular germ cell tumors usually present as scrotal swelling. Very rarely the primary is occult. Germ cell tumor frequently affects the undescended testis. However germ cell tumor of inguinal testis presenting as metastatic disease in neck
Sabera Tamboli   +2 more
doaj  

Testicular torsion in foals and stallions

open access: yesEquine Veterinary Education, EarlyView.
Summary Testicular torsion is a rare condition in horses characterised by a change in the position of the testis due to the testicular mesentery twisting around its own axis; it can occur both when the testis is still in the abdominal cavity and when it has descended into the scrotum.
C. P. Bartmann
wiley   +1 more source

Testicular Germ Cell Tumor Metastatic to the Right Atrium

open access: yes, 2011
P>We describe a right atrial metastasis of a testicular germ cell tumor, which was successfully removed from the tricuspid valve and subvalvular apparatus without the need for valve replacement. (J Card Surg 2011;26:276-279)
TÜRKÖZ, HÜSEYİN KEMAL   +3 more
core   +1 more source

Pattern‐based interpretation of SOX2 expression in ovarian teratomas: avoiding diagnostic pitfalls in the distinction between immature and mature neuroectodermal elements

open access: yesHistopathology, EarlyView.
Ovarian immature teratoma grading may be confounded by mature neuroectodermal mimics. SOX2 labelled immature neuroepithelium but also mature ependymal and glial tissue, while SALL4 was negative in mature mimics and variably expressed in immature neuroepithelium.
Agnese Orsatti   +14 more
wiley   +1 more source

Understanding extracellular vesicles in antiaging

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad   +3 more
wiley   +1 more source

PD-L1 expression in testicular germ cell tumors undergoing spontaneous regression

open access: yesBiomolecules & Biomedicine
Spontaneous regression of testicular germ cell tumors is a well-known phenomenon; however, the precise mechanisms of spontaneous regression are still unknown.
Ivan Novak   +8 more
doaj   +1 more source

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