Results 101 to 110 of about 5,712,508 (248)

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Treatment Strategy for Stage I Testicular Germ Cell Tumor [PDF]

, 2012
Most stage I testicular germ cell tumors are curable by orchiectomy alone. However, some tumors recur and require subsequent treatment. The point for the management of stage I testicular germ cell tumors is how to reduce the recurrence rate by ...
植村, 元秀, 中井, 康友, 永原, 啓, 野々村, 祝夫, 高山, 仁志   +4 more
core  

Improving the Understanding of Late Effects of Testicular Cancer in Adolescent and Young Adult Survivors: TRANSCEND‐XR

Andrology, EarlyView.
ABSTRACT Background Testicular cancer (TC) is the most common malignancy amongst adolescents and young adults (AYAs) aged 15–39 years assigned male at birth. Survivors often experience late effects of treatment and report unmet supportive care needs.
Mohamad M. Saab, Josephine Hegarty, Jack P. Gleeson, David Murphy, Sheena McHugh, Frances Shiely, Aileen Murphy, Ann Kirby, Ida J. Korfage, Sophie Terhaard, Agnes van der Heide, Johannes Sivesgaard, Matias Katajavaara Seidler, Anna Patrikidou, Davor Ježek, Lynda Corrigan, Patrice Kearney Sheehan, Daniele Raggi, Alison Reid, Michal Chovanec, Patrizia Gianntempo, Jourik A. Gietema, Justine Fleur van der Feen, Francisco Lupiáñez‐Villanueva, Ana Roca‐Umbert, Joanne Reid, Paulo Alves, Joana Soares, Karen Galvin, Michal Kubo, Maria O'Malley   +30 more
wiley   +1 more source

Rapid progression of a germ cell tumor encasing the inferior vena cava and aorta following a radical orchiectomy

Rare Tumors, 2013
Early stage testicular germ cell tumors are highly curable malignancies, but the need for close radiologic and biomarker surveillance is pivotal. Even in the setting of recurrence, rescue therapy has been successfully implemented.
Hekmat Hakiman, Sergio Huerta, Payal Kapur, Vitaly Margulis   +3 more
doaj   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source

The human germ cell lineage: pluripotency, tumourigenesis and proliferation

, 2008
EThOS - Electronic Theses Online ServiceGBUnited ...
Perrett, Rebecca Mary
core   +2 more sources

Is gynecomastia related to the disease characteristics and prognosis in testicular germ cell tumor patients?

Diagnostic and Interventional Radiology, 2019
PURPOSEWe aimed to assess the relationship between gynecomastia and tumor markers, histologic subtypes, and prognosis in patients with testicular germ cell tumors.METHODSThis study included 73 testicular germ cell cancer patients with pretreatment chest,
Ahmet Veysel Polat, Mesut Öztürk, İlkay Çamlıdağ, Behiç Akyüz   +3 more
doaj   +1 more source

Prognostic factors of metastatic testicular non-seminomatous germ cell tumors after chemotherapy

Journal of Cancer Research and Practice, 2018
Background: We evaluated the prognostic factors of metastatic testicular non-seminomatous germ cell tumor (NSGCT) after chemotherapy. Materials and methods: Data from 20 metastatic testicular NSGCT patients were retrospectively collected between January ...
Tzu-Yao Liao, Chuang-Chi Liaw, Cheng-Keng Chuang, Ying-Hsu Chang, Cheng-Lung Hsu, Meng-Ting Peng, John Wen-Cheng Chang   +6 more
doaj   +1 more source

Parallel Liquid Biopsy Analysis of miR‐371a‐3p and Cell‐Free DNA in an Unselected Cohort of Patients With Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background Despite robust data showing strong potential to improve diagnosis and disease monitoring in testicular germ cell tumors (TGCTs), miR‐371a‐3p testing has not yet been implemented in routine clinical practice. Cell‐free DNA (cfDNA) represents another promising liquid biopsy biomarker that may provide complementary molecular ...
Laura Matouskova, Romy Kralova, Eva Parobkova, Violeta Bakardjieva‐Mihaylova, Martina Zwyrtkova, Karolina Skvarova Kramarzova, Ludmila Boublikova   +6 more
wiley   +1 more source

Impact of Treatment Intensity on Quality of Life in Patients With Metastatic Testicular Cancer

Andrology, EarlyView.
ABSTRACT Introduction Testicular cancer (TC) is the most common malignancy in young men and is highly curable with platinum‐based chemotherapy. With growing survivorship rates, treatment‐related symptom burden and quality of life (QoL) have become increasingly important.
Pailin Pongratanakul, Tamim Hadjizada, Sophia Thy, Marieke Vermeulen‐Spohn, Günter Niegisch, Peter Albers, Yue Che   +6 more
wiley   +1 more source