Results 81 to 90 of about 5,712,508 (248)

Loss of TSLC1 causes male infertility due to a defect at the spermatid stage of spermatogenesis. [PDF]

, 2006
Tumor suppressor of lung cancer 1 (TSLC1), also known as SgIGSF, IGSF4, and SynCAM, is strongly expressed in spermatogenic cells undergoing the early and late phases of spermatogenesis (spermatogonia to zygotene spermatocytes and elongating spermatids to
Arends, Mark J., Affara, Nabeel, Adams, David J., Ellis, Peter J.I., Bradley, Allan, Chausiaux, Oriane E., van der Weyden, Louise, Surani, M. Azim, Lange, Ulrike C., Murakami, Yoshinori   +9 more
core   +1 more source

Testicular choriocarcinoma with pelvic and pulmonary metastases: a case report

Frontiers in Oncology
Testicular tumors represent a common form of solid tumor in young men, with choriocarcinoma of the testis being a rare, non-granulomatous germ cell tumor. It accounts for less than 0.3% of all testicular germ cell tumors.
Xin Bai, Xiao H. Liu, Hai W. Liang, Yi S. Li, Biao F. Shan, Jian M. Tang   +5 more
doaj   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source

Pure Adenocarcinoma with Intestinal Differentiation of The Testis as The First Presentation of a Testicular Teratoma: A Case Report with Literature Review of Management

Архивъ внутренней медицины
Pure adenocarcinoma is a somatic-type malignancy that comes from a germ cell tumor and is extremely rare but has been reported. It is usually seen as sarcoma, and less often as carcinoma. This rare phenomenon is generally attributed to the development of
Najla Saleh Ben Ghashir, Alingal Mohammed Babitha, Aref Chehal, Ashraf ALakkad   +3 more
doaj   +1 more source

Unilateral testicular seminoma with simultaneous contralateral torsion: a case report

Journal of Medical Case Reports, 2012
Introduction Testicular germ cell tumors are the most common malignancies in men. Testicular torsion is also a scrotal phenomenon seen in adolescence and adulthood. The co-occurrence of these two scrotal disorders is extremely rare.
Taguchil Kazumi, Yasui Takahiro, Naiki Taku, Umemoto Yukihiro, Kojima Yoshiyuki, Kawai Noriyasu, Tozawa Keiichi, Hayashi Yutaro, Kohri Kenjiro   +8 more
doaj   +1 more source

Impact of Chemotherapy on Sperm Functional Characteristics in Patients With Testicular Germ Cell Tumours

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec, Ondrej Simonik, Zuzana Kratka, Lukas Ded, Jana Vondrakova, Maryam Qasemi, Barbora Bryndova, Michala Krejci, Daniela Spevakova, Vishma Pratap Sur, Radomir Kren, Tomas Hradec, Pavel Skrobanek, Ludmila Boublikova, Libor Zamecnik, Tomas Buchler, Jiri Neuzil, Pavla Postlerova, Katerina Komrskova   +18 more
wiley   +1 more source

testicular germ cell tumor

, 2023
Supplementary Table S1: The list of 1,793 immune-related genes (IRGs) was collected from the IMMPORT database. Supplementary Table S2: The progression-free interval (PFI) data of TCGT. Supplementary Table S3: The list of highly amplified, over-expressed, and frequently mutated genes, 203 overlapping genes were identified as potential candidate TGCT ...
openaire   +2 more sources

In Situ Expression of miR‐371a‐3p and miR‐373‐3p in Testicular Germ Cell Tumours and Detection in Serum

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCTs) are the most common type of tumour diagnosed in young men, and reliable non‐invasive biomarkers are crucial for clinical management. MicroRNAs (miRNAs) from the miR‐371–373 cluster have recently been identified as novel and more sensitive serum biomarkers than the conventional protein‐based ...
Nina Mørup, Merve Tatli, Thomas Wagner, Helle Margit Albrechtsen, Gülizar Saritas, Gedske Daugaard, Sofia B. Winge, Kristian Almstrup   +7 more
wiley   +1 more source

The first reported case of a palpable and hypoechoic burned out testicular tumor

Nigerian Journal of Medicine, 2017
Primary extra gonadal germ cell tumors are rare. In case of the diagnosis of a midline retroperitoneal mass in a male, germ cell tumors should be taken into consideration.
Naser Yousefzade, Saeed Farhadi Niaki, Mojtaba Ameli, Leila Gholami Mahtaj   +3 more
doaj   +1 more source

Broader Familial Cancer Risk in Relatives of Testicular Cancer Patients: Insights From Two Mediterranean Populations

Andrology, EarlyView.
ABSTRACT Background Familial clustering of testicular germ cell tumour (TGCT) is well‐established, whereas the risk of non‐testicular cancer among relatives remains inconsistent across studies. Objective To evaluate the overall and site‐specific cancer risk among first‐degree relatives and grandparents of TGCT patients compared to cancer‐free controls.
Csilla Krausz, Chiara Abrardo, Viktoria Rosta, Daniel Moreno‐Mendoza, Luca Bressan, Matteo Vannucci, Rebecca Passerotti, Arianna Meacci, Ginevra Farnetani, Viola Bonini, Giovanni Corona, Maria Grazia Fino, Eduard Ruiz‐Castañé, Antoni Riera‐Escamilla   +13 more
wiley   +1 more source