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Immunotherapy in Testicular Germ Cell Tumors [PDF]

open access: goldFrontiers in Oncology, 2020
Testicular germ cell tumors (TGCTs) are malignancies with very high curative potential even in metastatic settings, mainly due to the introduction of cisplatin in the treatment of this disease.
Katarina Kalavska   +6 more
doaj   +4 more sources

Testicular mixed germ cell tumor in a newborn child: A rare case

open access: diamondJournal of Indian Association of Pediatric Surgeons, 2019
Testicular tumors are rare in children but highly treatable and usually curable. Seminomas are extremely rare in prepubertal children. Among nonseminomatous germ cell tumors, the most common are teratomas and yolk sac tumors. Mixed germ cell tumor (MGCT)
Aditya Pratap Singh   +5 more
doaj   +2 more sources

PD-L1 expression in testicular germ cell tumors undergoing spontaneous regression [PDF]

open access: yesBiomolecules & Biomedicine
Spontaneous regression of testicular germ cell tumors is a well-known phenomenon; however, the precise mechanisms of spontaneous regression are still unknown.
Ivan Novak   +8 more
doaj   +2 more sources

Organ-Sparing Surgery for Testicular Germ Cell Tumors: A Current Perspective [PDF]

open access: yesMedicina, 2023
Background and Objectives: We aimed to evaluate the oncological and functional outcomes of organ-sparing surgery for testicular germ cell tumors, a procedure that seeks to strike a balance between effective cancer control and organ preservation, in the ...
Esther García Rojo   +11 more
doaj   +2 more sources

The value of contrast-enhanced ultrasonography in differential diagnosis of primary testicular germ cell tumors and non-germ cell tumors over 50 years old

open access: yesFrontiers in Oncology, 2023
BackgroundUnlike young and middle-aged patients, seminoma is not common in patients with primary testicular tumors over the age of 50, so it cannot follow the general ideas and norms for diagnosing and treating testicular tumors, and its characteristics ...
Nianyu Xue   +3 more
doaj   +1 more source

Bilateral testicular germ cell tumors [PDF]

open access: yesTürk Üroloji Dergisi/Turkish Journal of Urology, 2013
Testicular cancer represents 1% to 1.5% of neoplasias in males and 5% of urologic tumors in general. The incidence of bilateral testicular tumors is 1-5%. Approximately one third of the cases are diagnosed as synchronous, while the other two thirds are diagnosed as metachronous tumors.
Haşmet, Sarıcı   +2 more
openaire   +2 more sources

Testicular germ cell tumor genomics [PDF]

open access: yesCurrent Opinion in Urology, 2017
Testicular germ cell tumors (TGCTs) are a model for curable cancer because of exquisite chemosensitivity and incorporation of multimodal therapy. Nevertheless, our ability to predict metastases in early-stage disease and responders to chemotherapy in advanced disease is limited. Treatment options for cisplatin-resistant disease are sparse.
Solomon L, Woldu   +2 more
openaire   +2 more sources

Lost in descent: Complications of cryptorchidism

open access: yesRadiology Case Reports, 2023
Cryptorchidism is a relatively common and important clinical entity and can lead to an array of downstream complications if it is not corrected in a timely manner, most notably with the development of testicular germ cell tumors.
Lauren Facer, MD   +2 more
doaj   +1 more source

Testicular cancer metastasis to the soft tissue: A case report and review of the literature

open access: yesRadiology Case Reports, 2021
While germ cell testicular cancer is rare and only accounts for 1% of cancers in males, it is the most common solid malignancy among men between 14 and 44 years of age.
Matthew A. Crain, BS   +5 more
doaj   +1 more source

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