Results 91 to 100 of about 70,701 (334)

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

BMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan, Ye Zhu, Zhi Ye, Huayang Zhang, Junxi Wang, Guozhong Yi, Zhiyong Li, Rongyang Xu, Luyao Wang, Zhenzhen Wu, Songtao Qi, Guanglong Huang, Shanqiang Qu   +12 more
wiley   +1 more source

Testicular Adrenal Rest Tumors: Sonographic and Magnetic Resonance Imaging Characteristics of Its Different Stages [PDF]

International Journal of Biomedicine
Testicular adrenal rest tumors (TARTs) are benign lesions that occur in a high percentage of patients with congenital adrenal hyperplasia and are characterized by the deficiency of adrenocortical enzymes, particularly 21-hydroxylase.
Mohamed Sherif El-Sharkawy
doaj   +1 more source

Cumulative Burden of Morbidity Among Testicular Cancer Survivors After Standard Cisplatin-Based Chemotherapy: A Multi-Institutional Study [PDF]

, 2018
Purpose In this multicenter study, we evaluated the cumulative burden of morbidity (CBM) among > 1,200 testicular cancer survivors and applied factor analysis to determine the co-occurrence of adverse health outcomes (AHOs).
AnnaLynn M. Williams, Christian Kollmannsberger, Chunkit Fung, Clair Beard, Darren R. Feldman, David J. Vaughn, Deepak M. Sahasrabudhe, Howard D. Sesso, Jeri Kim, Lawrence H. Einhorn, Lois B. Travis, Mohammad I. Abu Zaid, null null, Patrick O. Monahan, Robert A. Huddart, Robert J. Hamilton, Ryan Cook, Sarah L. Kerns, Shirin Ardeshir-Rouhani-Fard, Sophie D. Fossa, Timothy E. Stump   +20 more
core   +1 more source

Assessment of piRNA biogenesis and function in testicular germ cell tumors and their precursor germ cell neoplasia in situ

BMC Cancer, 2018
Aberrant overexpression of PIWI/piRNA pathway proteins is shown for many types of tumors. Interestingly, these proteins are downregulated in testicular germ cell tumors (TGCTs) compared to normal testis tissues. Here, we used germline and TGCT markers to
I. Gainetdinov, Y. Skvortsova, S. Kondratieva, Alexey Klimov, A. Tryakin, T. Azhikina   +5 more
semanticscholar   +1 more source

The ductal network in the human testis and epididymis: What belongs to which?

Clinical Anatomy, EarlyView.
Abstract The testes and epididymis are traversed by a system of tubules in which sperm cells are generated, matured, nourished, and transported. Among these are the efferent ductules, which connect the rete testis to the duct of the epididymis. In the Terminologia Anatomica (TA), the efferent ductules are assigned to the testicles, while numerous ...
Andreas Gocht, Axel Stuart Merseburger, Süleyman Ergün, Marie Christine Roesch   +3 more
wiley   +1 more source

Unilateral testicular seminoma with simultaneous contralateral torsion: a case report

Journal of Medical Case Reports, 2012
Introduction Testicular germ cell tumors are the most common malignancies in men. Testicular torsion is also a scrotal phenomenon seen in adolescence and adulthood. The co-occurrence of these two scrotal disorders is extremely rare.
Taguchil Kazumi, Yasui Takahiro, Naiki Taku, Umemoto Yukihiro, Kojima Yoshiyuki, Kawai Noriyasu, Tozawa Keiichi, Hayashi Yutaro, Kohri Kenjiro   +8 more
doaj   +1 more source

Extranodal diffuse large B‐cell lymphoma: Clinical and molecular insights with survival outcomes from the multicenter EXPECT study

Cancer Communications, EarlyView.
Abstract Background Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of aggressive non‐Hodgkin's lymphoma with distinct clinical and molecular heterogeneity. DLBCL that arises in extranodal organs is particularly linked to poor prognosis. This study aimed to determine the clinical and molecular characteristics of extranodal involvement (
Si‐Yuan Chen, Peng‐Peng Xu, Ru Feng, Guo‐Hui Cui, Li Wang, Shu Cheng, Rong‐Ji Mu, Hui‐Lai Zhang, Xiao‐Lei Wei, Yong‐Ping Song, Kai‐Yang Ding, Li‐Hua Dong, Zun‐Min Zhu, Shen‐Miao Yang, Xin Wang, Ting‐Bo Liu, Jian‐Da Hu, Xiao‐Yun Zheng, Ou Bai, Jing‐Yan Xu, Liang Huang, Wei Sang, Ke‐Qian Shi, Fan Zhou, Fei Li, Ai‐Bin Liang, Hui Zhou, Si‐Guo Hao, Hong‐Hui Huang, Bin Xu, Wen‐Bin Qian, Cai‐Xia Li, Zhi‐Ming Li, Chong‐Yang Wu, Xiao‐Bo Wang, Wen‐Yu Shi, Shu‐Ye Wang, Yu‐Yang Tian, Xi Zhang, Ke‐Shu Zhou, Li‐Juan Cui, Hui Liu, Huo Tan, Qing Leng, Dong‐Lu Zhao, Ting Niu, Wei‐Li Zhao   +46 more
wiley   +1 more source

Male reproductive health and environmental xenoestrogens [PDF]

, 1996
EHP is a publication of the U.S. government. Publication of EHP lies in the public domain and is therefore without copyright. Research articles from EHP may be used freely; however, articles from the News section of EHP may contain photographs or ...
A Giwercman, Ansell PE, Avellan L, B Jégou, Baird DD, Baumrucker GO, Berkowitz GD, Berkowitz GS, Bibbo M, Bigler WJ, Bj N, Blom K, Bostofte E, Bradbury RB, Bromage NR, Brown LM, Buemann B, Campbell DM, Cassidy A, Chung CS, Clemens MJ, Conover MR, Copeland PA, Czeizel A, Depue RH, Driscoll SG, E Rajpert-De Meyts, Forman D, Fox GA, Freeman HC, Frst P, Fry DM, Gray LEJ, Gray LEJ, Greco TL, H Leffers, Hakulinen T, Halevi HS, Harris LE, Hautau ER, Henderson BE, Hirasing RA, Hohlbein R, Hsieh J-T, Ikeda Y, J A McLachlan, J C Larsen, J Müller, J Sumpter, J Toppari, Jennings ML, Jost A, Kallen B, Kallen B, Korach KS, Kupfer D, L J Guillette, Leatherland JF, Leatherland JF, McDonnell DP, McIntosh R, N E Skakkebaek, N Keiding, Newbold RR, O Meyer, P Christiansen, P Grandjean, P Jouannet, Panayotou PC, Pearce N, Peterson RE, Pohjanvirta R, R Sharpe, Rey RA, Schumacher GFB, Scully RE, Sell S, Soto AM, Sweet RA, T K Jensen, T Scheike, Thomas KB, Thomas KB, Thorup J, Tryphonas L, Turscott B, Vessey MP, Wallace HM, Ward B, Wilkinson TJ   +89 more
core   +2 more sources

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

An unusual cause of gynaecomastia in a male [PDF]

, 2019
Summary: Beta-human chorionic gonadotropin (βhCG) is normally produced by syncytiotrophoblasts of the placenta during pregnancy and aids embryo implantation.
Bano, G, Beharry, N, Du Parcq, J, Hameed, A, Rehman, T   +4 more
core   +1 more source