Results 121 to 130 of about 70,701 (334)

Benign cystic Teratoma and Gonadoblastoma developed in bilateral abdominal undescended testis

Urology Case Reports, 2022
Cryptorchidism is one of the most common congenital malformations in humans and one of its most important consequences is the development of testicular cancer.
Hormoz Karami, Omid Aminirad, Mahmoud Akhavan Tafti   +2 more
doaj  

Leydig cell tumor of testis in a child: An uncommon presentation

Journal of Indian Association of Pediatric Surgeons, 2017
Leydig cell tumors (LCTs) are rare testicular tumors. Incidence is 1%–3% of all testicular neoplasms, bilateral in 10%. They are frequently hormonally active, leading to feminizing or virilizing syndromes.
Madhumita Mukhopadhyay, Chhanda Das, Sucharita Sarkar, Biswanath Mukhopadhyay, Bedabrata Mukhopadhyay, Rishavdeb Patra   +5 more
doaj   +1 more source

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source

Testicular mixed germ cell tumor in a newborn child: A rare case

Journal of Indian Association of Pediatric Surgeons, 2019
Testicular tumors are rare in children but highly treatable and usually curable. Seminomas are extremely rare in prepubertal children. Among nonseminomatous germ cell tumors, the most common are teratomas and yolk sac tumors. Mixed germ cell tumor (MGCT)
Aditya Pratap Singh, Ramesh Tanger, Deepika Mishra, Maryem Ansari, Arun Kumar Gupta, Arvind Kumar Shukla   +5 more
doaj   +1 more source

ErbBs inhibition by lapatinib blocks tumor growth in an orthotopic model of human testicular germ cell tumor [PDF]

, 2018
In this work, we have analyzed the expression of different members of the ErbB family in human samples of testicular germ cell tumors (GCTs). We observed expression of ErbB1 or ErbB2 in different tumor subtypes, but we also found high expression of ErbB3
Casanovas i Casanovas, Oriol, Castillo-Ávila, Wilmar, Condom i Mundó, Enric, García del Muro Solans, Xavier, Germà Lluch, José Ramón, Graupera i Garcia-Milà, Mariona, Hernández-Losa, Javier, Juliachs Milà, Mercè, Pandiella, Atanasio, Piulats, Josep M., Teixidó, C., Vidal-Bel, August, Villanueva Garatachea, Alberto, Viñals Canals, Francesc   +13 more
core   +1 more source

Increased tumor vascularization is associated with the amount of immune competent PD-1 positive cells in testicular germ cell tumors

Oncology Letters, 2018
Testicular germ cell cancer in a metastatic state is curable with a cisplatin-based first line chemotherapy. However, 10–15% of these patients are resistant to first line chemotherapy and are thus left with only palliative options.
L. Jennewein, G. Bartsch, K. Gust, H. Kvasnicka, A. Haferkamp, R. Blaheta, M. Mittelbronn, P. Harter, J. Mani   +8 more
semanticscholar   +1 more source

A non‐hormonal reversible contraceptive targeting GSK3α, a protein kinase, essential for epididymal sperm maturation

Andrology, EarlyView.
Abstract Background and objectives Epididymal transit renders key competence to mammalian spermatozoa for fertilizing eggs. Generally, the two paralogs of glycogen synthase kinase 3, GSK3α and GSK3β, functionally overlap except in testis and sperm. We showed that GSK3α is essential for epididymal sperm maturation and fertilization.
Mustfa Kabi, Aditi Khamamkar, Kwaku Kyei‐Baffour, Michel Weïwer, Srinivasan Vijayaraghavan, Souvik Dey   +5 more
wiley   +1 more source

Risk stratification for venous thromboembolism in patients with testicular germ cell tumors

PLoS ONE, 2016
Background Patients with testicular germ cell tumors (TGCT) have an increased risk for venous thromboembolism (VTE). We identified risk factors for VTE in this patient cohort and developed a clinical risk model. Methods In this retrospective cohort study
A. Bezan, F. Posch, F. Ploner, T. Bauernhofer, M. Pichler, J. Szkandera, G. Hutterer, K. Pummer, T. Gary, H. Samonigg, J. Beyer, T. Winder, T. Hermanns, C. Fankhauser, A. Gerger, M. Stotz   +15 more
semanticscholar   +1 more source

First application of three‐dimensional light sheet fluorescence microscopy to human testicular tumors: New perspectives in histopathology

Andrology, EarlyView.
Abstract Background Testicular tumors are among the most frequently diagnosed cancers in young men. The consequences of this diagnosis are orchiectomies, severely restricting fertility. For these young patients, a comprehensive diagnostics would be desirable, achieving a refined diagnosis and improved therapeutic patient stratification.
Diana Pinkert‐Leetsch, Ahmad Kareem, Simon F. Merz, Marc Teckentrup, Alexander Fichtner, Felix Bremmer, Jeannine Missbach‐Guentner   +6 more
wiley   +1 more source

Age-related biological features of germ cell tumors. [PDF]

, 2013
Germ cell tumors (GCTs) are rare but clinically and pathologically diverse tumors that occur in an extensive range of age groups, from children to older adults and which include both seminomatous and nonseminomatous tumors.
Coleman, Nicholas, Collinson, Kate, Cummings, Michele, Joffe, Johnathan K, Murray, Matthew J, Orsi, Nicolas M, Shipley, Janet, Stark, Daniel   +7 more
core   +3 more sources