Results 11 to 20 of about 70,701 (334)
Absence of microsatellite instability and BRAF (V600E) mutation in testicular germ cell tumors [PDF]
Andrology, 2016 Testicular germ cell tumors (TGCT) are the most common malignant neoplasm in young men. DNA mismatch repair deficiency can lead to microsatellite instability (MSI), an important mechanism of genetic instability.
Basto +46 more
core +2 more sources
Frontiers in Oncology, 2023 BackgroundUnlike young and middle-aged patients, seminoma is not common in patients with primary testicular tumors over the age of 50, so it cannot follow the general ideas and norms for diagnosing and treating testicular tumors, and its characteristics ...
Nianyu Xue +3 more
doaj +1 more source
Epigenetics and testicular germ cell tumors.
Gene, 2018 Abstract Malignant testicular germ cell tumors (TGCTs) are the most frequent testicular cancers in Caucasian males, developing at the most productive age of man. We are briefly reviewing TGCT-tumorigenesis with an emphasis on epigenetics. Epigenetic mechanisms such as DNA methylation and histone modifications together with RNA interference that all ...
R. Buljubašić +7 more
semanticscholar +8 more sources
miRNAs and Biomarkers in Testicular Germ Cell Tumors: An Update
International Journal of Molecular Sciences, 2021 Testicular germ cell tumors (TGCTs) are the leading form of solid cancer and death affecting males between the ages of 20 and 40. Today, their surgical resection and chemotherapy are the treatments of first choice, even if sometimes this is not enough to
Marco De Martino +2 more
semanticscholar +1 more source
Somatic-type Malignancies in Testicular Germ Cell Tumors
American Journal of Surgical Pathology, 2021 The development of somatic-type malignancies (SMs) in testicular germ cell tumors (GCTs) is a rare but well-recognized phenomenon. We studied the pathologic features of 63 GCTs with SMs in the testis (n=22) or metastases (n=41) and correlated these ...
Michael J. Hwang +6 more
semanticscholar +1 more source
Fertility in men with testicular germ cell tumors [PDF]
Fertility and Sterility, 2003 To assess the prevalence of fertility or infertility in men before and after treatment for unilateral testicular cancer. The results were compared with the lifetime prevalence of infertility in the general population (20%-28%).Survey.University referral center for testicular cancer.Two hundred twenty-six patients treated for testicular cancer ...
J.R. Spermon +5 more
openalex +4 more sources
Acta oncologica, 2020 Introduction: To minimize the radiation exposure of mostly young testicular cancer patients, it is essential to find out whether CT could be replaced by magnetic resonance imaging (MRI) in the staging and follow-up of the patients.
M. Laukka +4 more
semanticscholar +1 more source
Bilateral testicular germ cell tumors [PDF]
Türk Üroloji Dergisi/Turkish Journal of Urology, 2013 Testicular cancer represents 1% to 1.5% of neoplasias in males and 5% of urologic tumors in general. The incidence of bilateral testicular tumors is 1-5%. Approximately one third of the cases are diagnosed as synchronous, while the other two thirds are diagnosed as metachronous tumors.
Muzaffer Eroglu +2 more
openaire +2 more sources
Retroperitoneal germ cell tumor, primary or secondary: A diagnostic conundrum
MGM Journal of Medical Sciences, 2023 Germ cell tumor, seminoma, is the most common cancer in young men’s testis. However, a small subset of tumors (1%–2%) originate in other locations and are referred to as primary extragonadal germ cell tumors. But such type of tumors’ origin is thought to
Surabhi Singh +4 more
doaj +1 more source
Development of CNS-type Primitive Neuroectodermal Tumor in Metastatic Testicular Mixed Germ Cell Tumor. [PDF]
, 2016 A 29-year-old man presenting with a retroperitoneal mass was found to have a testis lesion consistent with mixed germ cell tumor and the RPLND specimen showed teratoma with an area of central nervous system-type primitive neuroectodermal tumor (PNET) not
Meng, Maxwell V +2 more
core +5 more sources