Results 61 to 70 of about 331,784 (343)
Advanced Science, Volume 12, Issue 28, July 24, 2025.In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang +10 more
wiley +1 more source
Effect of recombinant human vascular endothelial growth factor on testis tissue xenotransplants from prepubertal boys: a three-case study [PDF]
, 2019 Research question Does recombinant human vascular endothelial growth factor (VEGF-165) improve the efficiency of human immature testis tissue (ITT) xenotransplantation?
Goossens, Ellen +5 more
core +1 more source
Cancer, 1970 The prognosis for lymphoma clinically localized to the testis at the time of original diagnosis is relatively favorable after orchiectomy and radiation therapy to the regional lymph nodes the previously held belief that life expectancy is poor for men with testicular lymphoma was due to failure in most reports to separate survival of those with ...
David C. Utz +3 more
openaire +3 more sources
Advanced Science, EarlyView.This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan +6 more
wiley +1 more source
Haematologica, 2011 Background In multiple myeloma, expression of cancer testis antigens may provide prognostic markers and potential targets for immunotherapy. Expression at relapse has not yet been evaluated for a large panel of cancer testis antigens which can be ...
Mark van Duin +11 more
doaj +1 more source
Methylation of the Gpat2 promoter regulates transient expression during mouse spermatogenesis [PDF]
, 2015 Spermatogenesis is a highly regulated process that involves both mitotic and meiotic divisions, as well as cellular differentiation to yield mature spermatozoa from undifferentiated germinal stem cells.
Cattaneo, Elizabeth Renee +6 more
core +2 more sources
Advanced Science, EarlyView.This study reports for the first time an oral targeted nanomedicine that conducts ion exchange through engineered Ganoderma‐derived extracellular vesicle, managing both the in‐copper and ex‐copper in a multi‐pronged approach, offering a promising therapeutic strategy for addressing WD with reproductive dysfunction.
Tingting Wang +12 more
wiley +1 more source
Laboratory Animal Research, 2016 Descending of the testes is an important process for spermatogenesis and cryptorchidism is one of the most relevant genital defects in dogs. In a previous study, we observed abnormal morphology and proliferation of Sertoli cells in a cryptorchid testis ...
Hyo Young Jung +7 more
doaj +1 more source
An unexpected long-term complication of genital burn in a child: Secondary cryptorchidism [PDF]
, 2018 Genital and perineal burns are rare and challenging injuries with serious long-term complications. Involvement of the testes is a sign of severity. There is limited knowledge in the literature about the management of complications and testes involvement ...
Deliağa, H. +3 more
core +1 more source
A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche
Advanced Science, EarlyView.A hydrogel microneedle‐based system enables whole testicular cultivation, supporting spermatogonial proliferation and enhancing spermatogenesis in vitro. This ‘whole testicular spermatogonia pool’ (WTSP) significantly increases spermatid production and fertility potential in mice. This system also promotes spermatogonial expansion in human fetal testes,
Yu Xia +14 more
wiley +1 more source