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Testosterone deficiency (TD) afflicts approximately 30% of men aged 40-79 years, with an increase in prevalence strongly associated with aging and common medical conditions including obesity, diabetes, and hypertension. A strong relationship is noted between TD and metabolic syndrome, although the relationship is not certain to be causal.
Abdulmaged M, Traish +3 more
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Alternatives to testosterone replacement: testosterone restoration
The European Male Aging Study has demonstrated that the hypogonadism of male aging is predominantly secondary. Theoretically with appropriate stimulation from the pituitary, the aging testis should be able to produce eugonadal levels of testosterone. The
Andrew McCullough
doaj +3 more sources
Sustained testosterone suppression: prognostic indicator in advanced hormone sensitive prostate cancer [PDF]
ObjectiveWe aimed to investigate the relationship between sustained testosterone suppression and clinical outcomes in advanced hormone-sensitive prostate cancer (aHSPC), which integrates longitudinal testosterone with castration duration to predict tumor
Dongsheng Ma +4 more
doaj +2 more sources
A Review of foods and food supplements increasing testosterone levels [PDF]
Androgens are essential for male physical activity. Age-related androgen deficiency, known as late-onset hypogonadism (LOH), is considered a risk factor for several diseases. There are many men’s health supplements on the market.
Tomoya Kataoka +2 more
doaj +1 more source
Testosterone undecanoate is a hormone agent with long-acting potential and is used for testosterone replacement therapy for hypogonadism. This study was designed to investigate application of testosterone undecanoate in maintaining high androgen levels ...
Jinho An, Hyunseok Kong
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Objective To investigate whether routine assessment of free testosterone improves the diagnostic accuracy of functional hypogonadism. Methods Total and free testosterone (calculated on SHBG levels) were determined in 188 patients with sexual symptoms and
Paolo Facondo +5 more
doaj +1 more source
Testosterone Deficiency Associated with Poor Glycemic Control in Korean Male Diabetics [PDF]
BackgroundRecent studies have shown that men with diabetes have lower testosterone levels than healthy men. However, studies on the correlation between testosterone and diabetes are rare in Korea.
Joo-Sung Kim +4 more
doaj +1 more source
Background Attention deficit/hyperactivity disorder (ADHD) entails inattention, impulsivity, and restlessness at a disabling level. The pharmacological treatment of ADHD rests on the use of centrally acting stimulants, such as methylphenidate and D ...
Ane Rogne, Bjørnar Hassel
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Serum Total Testosterone and Premature Mortality Among Men in the USA
The relationship between testosterone and premature mortality has caused recent controversy. While previous studies have demonstrated mixed results, this is partly because of variable patient populations, different testosterone thresholds, and the use of
Richard J. Fantus +6 more
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Barriers to diagnosis and accessing effective treatment and support for testosterone deficiency [PDF]
Testosterone deficiency is common but often undiagnosed and untreated with many men struggling with symptoms for years before reaching out for healthcare professional advice. In order to gain an holistic view of the barriers to men accessing effective
Janine David, Alexandra Charles
doaj +1 more source

