Results 11 to 20 of about 169,506 (312)
We have successfully characterized the structure of testosterone, one of the essential steroids, through high-resolution rotational spectroscopy. A single conformer has been detected, and a total of 404 transitions have been fitted, allowing a precise determination of the rotational constants.
Iker León+3 more
openaire +5 more sources
Testosterone and the Heart [PDF]
The development of a subnormal level of testosterone (T) is not universal in ageing men, with 75% of men retaining normal levels. However, a substantial number of men do develop T deficiency (TD), with many of them carrying a portfolio of cardiovascular (CV) risk factors, including type 2 diabetes (T2D) and the metabolic syndrome. TD increases the risk
Sudarshan Ramachandran+2 more
openaire +3 more sources
Testosterone and Sarcopenia [PDF]
Aging affects metabolism, leading to physiological and functional impairments, and is also related to changes in body composition, including reduced skeletal muscle mass and increased body fat. These changes are correlated with the pathophysiology of sarcopenia, which is defined as age-related loss of skeletal muscle mass and strength. Low testosterone
Myung Jun Shin+2 more
openaire +2 more sources
A Mn catalyst has been rationally redesigned to repel sp3hybridised substituents while attracting sp2 substituents, and hence enable enantioselective hydrogenation of cyclic ketones. DFT calculations enable a robust prediction of the level of enantiocontrol across a range of substrates.
Conor L. Oates+3 more
wiley +1 more source
Accessible ecophysiological tools for seabird conservation
Abstract Seabirds are the most endangered avian taxa on Earth, with over a third of species globally threatened. To help slow their decline, conservation physiology seeks to determine how seabird responses to climatic and anthropogenic threats influence demographic processes, but it is not widely utilized in monitoring.
Edin A. Whitehead, Brendon J. Dunphy
wiley +1 more source
Abstract A lack of understanding of the mechanisms underlying osteoarthritis (OA) progression limits the development of effective long‐term treatments. Quantitatively tracking spatiotemporal patterns of cartilage and bone degeneration is critical for assessment of more appropriately targeted OA therapies.
Deva D. Chan+8 more
wiley +1 more source
Risk of osteoporosis in testicular germ cell tumour survivors: A systematic review of the literature
Abstract Context Testicular germ cell tumour (TGCT) survivors are potentially at risk of developing osteoporosis, because of increased risk for disturbed bone remodelling associated with hypogonadism and anti‐cancer treatment. A number of studies show bone loss and increased fracture risk in TGCT survivors, but data are scarce.
Josephina P. M. Vrouwe+4 more
wiley +1 more source
Abstract Metformin, the first line pharmacotherapy for type 2 diabetes has demonstrated favourable effects in prostate cancer (PCa) across a range of studies evaluating PCa patient outcomes amongst metformin users. However, a lack of rigorously conducted prospective studies has stalled clinical use in this setting.
Nan Fang Wang+3 more
wiley +1 more source
Aims: Low plasma testosterone levels have been shown to predict worse outcome in men with severe atherosclerotic disease. We hypothesized that a low plasma testosterone level affects disease risk through changes in gene expression in atherosclerotic ...
Floor Groepenhoff+9 more
doaj +1 more source