Results 31 to 40 of about 312,372 (339)

Safety Aspects and Rational Use of Testosterone Undecanoate in the Treatment of Testosterone Deficiency: Clinical Insights

Drug, Healthcare and Patient Safety, 2023
Katherine Campbell,1 Akhil Muthigi,1 Armin Ghomeshi,2 Kyle Schuppe,3 Max D Sandler,4 Ranjith Ramasamy1 1Desai Sethi Urology Institute, University of Miami, Miami, Fl, 33136, USA; 2Herbert Wertheim College of Medicine, Florida International University ...
Campbell K, Muthigi A, Ghomeshi A, Schuppe K, Sandler MD, Ramasamy R   +5 more
doaj  

Testosterone concentrations and prescription patterns of 1% testosterone gel in transgender and gender diverse individuals

Therapeutic Advances in Endocrinology and Metabolism, 2022
Background: Masculinising hormone therapy with testosterone is used to align an individual’s physical characteristics with their gender identity. Standard testosterone doses and formulations recommended for hypogonadal cisgender men are typically ...
Brendan J. Nolan, Sav Zwickl, Alex F. Q. Wong, Peter Locke, Satu Simpson, Ling Li, Jeffrey D. Zajac, Ada S. Cheung   +7 more
doaj   +1 more source

Effects of Testosterone Treatment in Older Men.

New England Journal of Medicine, 2016
BACKGROUND Serum testosterone concentrations decrease as men age, but benefits of raising testosterone levels in older men have not been established. METHODS We assigned 790 men 65 years of age or older with a serum testosterone concentration of less ...
Peter J Snyder, S. Bhasin, Glenn R. Cunningham, Alvin M. Matsumoto, A. Stephens-Shields, Jane A. Cauley, Thomas M Gill, E. Barrett-Connor, Ronald S. Swerdloff, Christina Wang, Kristine E Ensrud, Cora E Lewis, John T Farrar, D. Cella, Raymond C Rosen, M. Pahor, Jill P. Crandall, M. Molitch, Denise Cifelli, Darlene Dougar, Laura Fluharty, Susan M. Resnick, T. Storer, S. Anton, S. Basaria, S. Diem, Xiaoling Hou, Emile R. Mohler, J. Kellogg Parsons, N. K. Wenger, B. Zeldow, J. Richard Landis, Susan S. Ellenberg   +32 more
semanticscholar   +1 more source

Testosterone and the heart [PDF]

International Journal of Clinical Practice, 2012
Several large scale studies in recent years have demonstrated increased cardiovascular mortality in men with low testosterone, especially those with existing cardiovascular disease and type 2 diabetes. In some patients the baseline measurement was a single total testosterone level, in others the association was seen only with free or bioavailable ...
openaire   +3 more sources

Free Testosterone Reflects Metabolic as well as Ovarian Disturbances in Subfertile Oligomenorrheic Women

International Journal of Endocrinology, 2018
Background. Diagnosing polycystic ovary syndrome (PCOS) is based on ovulatory dysfunction, ovarian ultrasound data, and androgen excess. Total testosterone is frequently used to identify androgen excess, but testosterone is mainly bound to sex hormone ...
L. Antonio, S. Pauwels, M. R. Laurent, D. Vanschoubroeck, I. Jans, J. Billen, F. Claessens, B. Decallonne, Diane De Neubourg, P. Vermeersch, D. Vanderschueren   +10 more
doaj   +1 more source

Association of Testosterone Treatment With Alleviation of Depressive Symptoms in Men: A Systematic Review and Meta-analysis

JAMA psychiatry, 2019
Importance Countering depressive disorders is a public health priority. Currently, antidepressants are the first-line treatment, although they show modest effects. In men, testosterone treatment is a controversial alternative or adjunct treatment option.
A. Walther, J. Breidenstein, Robert Miller   +2 more
semanticscholar   +1 more source

Serum Testosterone and Cortisol Concentrations After Single-Dose Administration of 100-Mg Transdermal Testosterone in Healthy Men

Frontiers in Pharmacology, 2019
The growing interest in testosterone's effects on men's social behaviors, in particular aggressive, risk-taking, or status maintenance behaviors, is accompanied by a paucity of dose-dependent pharmacokinetic data. Examining the neurophysiological effects
Andrei A. Puiu, Andrei A. Puiu, Sina Radke, Mikhail Votinov, Mikhail Votinov, Ute Habel, Ute Habel, Beate Herpertz-Dahlmann, Bruce Turetsky, Kerstin Konrad, Kerstin Konrad   +10 more
doaj   +1 more source

A Reappraisal of Testosterone's Binding in Circulation: Physiological and Clinical Implications.

Endocrine reviews, 2017
In the circulation, testosterone and other sex hormones are bound to binding proteins, which play an important role in regulating their transport, distribution, metabolism, and biological activity. According to the free hormone hypothesis, which has been
A. Goldman, S. Bhasin, Frederick C W Wu, M. Krishna, A. Matsumoto, Ravi Jasuja   +5 more
semanticscholar   +1 more source

Testosterone trajectories and reference ranges in a large longitudinal sample of male adolescents.

PLoS ONE, 2014
PurposePubertal dynamics plays an important role in physical and psychological development of children and adolescents. We aim to provide reference ranges of plasma testosterone in a large longitudinal sample.
Ammar Khairullah, Laura Cousino Klein, Suzanne M Ingle, Margaret T May, Courtney A Whetzel, Elizabeth J Susman, Tomáš Paus   +6 more
doaj   +1 more source

Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells

Journal of Cell Biology, 2018
Testosterone is indispensable for sexual development and maintaining male characteristics, and deficiency of this hormone results in primary or late-onset hypogonadism (LOH).
Fengyi Gao, Guoping Li, Chao Liu, Hui Gao, Hao Wang, Weixiao Liu, Min Chen, Yongliang Shang, Lina Wang, Jian Shi, Wenlong Xia, Jianwei Jiao, F. Gao, Jian Li, Liang Chen, Wei Li   +15 more
semanticscholar   +1 more source