Results 31 to 40 of about 169,506 (312)
International Journal of Endocrinology, 2018 Background. Diagnosing polycystic ovary syndrome (PCOS) is based on ovulatory dysfunction, ovarian ultrasound data, and androgen excess. Total testosterone is frequently used to identify androgen excess, but testosterone is mainly bound to sex hormone ...
L. Antonio +10 more
doaj +1 more source
The World Journal of Men's Health, 2023 Purpose: Testosterone replacement therapy (TRT) can potentially cause decreased spermatogenesis and subsequent infertility. Recent studies have suggested that 17-hydroxyprogesterone (17-OHP) is a reliable surrogate for intratesticular testosterone (ITT)
Parris Diaz +7 more
doaj +1 more source
Time-varying testosterone level and risk of myocardial infarction and stroke among hypogonadal men: a longitudinal study in Germany [PDF]
Journal of Men's Health, 2022 Background and objective: Findings on the association between testosterone and cardiovascular risk in men have been inconsistent. Previous studies investigated this association based on testosterone level measured at one single point in time (e.g ...
Xiao Zhang +7 more
doaj +1 more source
Testosterone and the heart [PDF]
International Journal of Clinical Practice, 2012 Several large scale studies in recent years have demonstrated increased cardiovascular mortality in men with low testosterone, especially those with existing cardiovascular disease and type 2 diabetes. In some patients the baseline measurement was a single total testosterone level, in others the association was seen only with free or bioavailable ...
openaire +4 more sources
Drug Testing and Analysis, Volume 14, Issue 11-12, Page 1864-1870, November-December 2022., 2022 The detection of putative 18‐methyl‐19‐norandrosterone in a forensic urine sample has triggered a follow‐up investigation. Doping substances in the possession of the suspect were examined with regard to possible precursor steroids. 18‐Methyl‐19‐nortestosterone proved to be a suitable marker for reliable detection in doping analysis.
Detlef Thieme +5 more
wiley +1 more source
, 2021 Testosterone is a hormone produced majorly by the testicles in adult human _ men. The hormone affects a man’s appearance and sexual development, stimulates sperm production and regulates a man’s sex drive. It also helps build muscles and bone mass. Testosterone production decreases with age.
Irene Porcari +2 more
openaire +4 more sources
Therapeutic Advances in Endocrinology and Metabolism, 2022 Background: Masculinising hormone therapy with testosterone is used to align an individual’s physical characteristics with their gender identity. Standard testosterone doses and formulations recommended for hypogonadal cisgender men are typically ...
Brendan J. Nolan +7 more
doaj +1 more source
Hormonal Factors Moderate the Associations Between Vascular Risk Factors and White Matter Hyperintensities [PDF]
arXiv, 2022 Objective: To examine the moderation effects of hormonal factors on the associations between vascular risk factors and white matter hyperintensities (WMH) in men and women, separately. Methods: WMH were automatically segmented and quantified in the UK Biobank dataset (N = 18,294). Generalised linear models were applied to examine 1) the main effects of
arxiv
Profiling of FSHR Negative Allosteric Modulators on LH/CGR Reveals Biased Antagonism with Implications in Steroidogenesis [PDF]
Molecular and Cellular Endocrinology, 436:10--22 (2016), 2018 Biased signaling has recently emerged as an interesting mean to modulate the function of many G protein-coupled receptors (GPCRs). Previous studies reported two negative allosteric modulators (NAMs) of follicle-stimulating hormone receptor (FSHR), ADX68692 and ADX68693, with differential effects on FSHR-mediated steroidogenesis and ovulation.
arxiv +1 more source
Frontiers in Pharmacology, 2019 The growing interest in testosterone's effects on men's social behaviors, in particular aggressive, risk-taking, or status maintenance behaviors, is accompanied by a paucity of dose-dependent pharmacokinetic data. Examining the neurophysiological effects
Andrei A. Puiu +10 more
doaj +1 more source