Results 51 to 60 of about 502,065 (385)

Testicular endocrine activity is upregulated by D-Aspartic acid in the green frog Rana esculenta [PDF]

open access: yes, 2004
This study investigated the involvement of D-aspartic acid (D-Asp) in testicular steroidogenesis of the green frog Rana esculenta and its effect on stimulation of thumb pad morphology and glandular activity, a typical testosterone-dependent secondary ...
ASSISI, LOREDANA   +5 more
core   +1 more source

Association of Testosterone Treatment With Alleviation of Depressive Symptoms in Men: A Systematic Review and Meta-analysis

open access: yesJAMA psychiatry, 2019
Importance Countering depressive disorders is a public health priority. Currently, antidepressants are the first-line treatment, although they show modest effects. In men, testosterone treatment is a controversial alternative or adjunct treatment option.
A. Walther   +2 more
semanticscholar   +1 more source

Effect of soy in men with type 2 diabetes mellitus and subclinical hypogonadism: a randomised controlled study [PDF]

open access: yes, 2016
Context: Isoflavones found in soy products have a chemical structure similar to estrogen, leading to concerns of an adverse estrogenic effect in men, particularly in those with type 2 diabetes mellitus (T2DM) who have low testosterone levels due to ...
Atkin, Stephen L.   +5 more
core   +1 more source

Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells

open access: yesJournal of Cell Biology, 2018
Testosterone is indispensable for sexual development and maintaining male characteristics, and deficiency of this hormone results in primary or late-onset hypogonadism (LOH).
Fengyi Gao   +15 more
semanticscholar   +1 more source

The Anti-Inflammatory Effects of Testosterone

open access: yesJournal of the Endocrine Society, 2018
Low plasma testosterone (T) levels correlated with metabolic syndrome, cardiovascular diseases, and increased mortality risk. T exerts a significant effect on the regulation of adipose tissue accumulation, and in the glucose and lipids metabolism ...
V. Bianchi
semanticscholar   +1 more source

Fabrication of silastic testosterone enanthate implants to achieve virilizing levels of serum testosterone in swine

open access: yesMethodsX
The aim of this study was to create a continuous drug delivery system that would yield serum testosterone levels in sexually mature, female pigs consistent with serum testosterone levels of human transgender men.
Nirvana Mahabir, Annie E. Newell-Fugate
doaj   +1 more source

Testosterone protects mice against zika virus infection and suppresses the inflammatory response in the brain

open access: yesiScience, 2022
Summary: Testosterone is essential to human growth and development as well as immune regulation. Zika virus (ZIKV), an emerging arbovirus associated with neurological complications including neuroinflammation, can also cause testicular damage and ...
Bohan Zheng   +8 more
doaj   +1 more source

Transcriptomic and lipid profiling analysis reveals a functional interplay between testosterone and growth hormone in hypothyroid liver

open access: yesFrontiers in Endocrinology, 2023
Preclinical and clinical studies suggest that hypothyroidism might cause hepatic endocrine and metabolic disturbances with features that mimic deficiencies of testosterone and/or GH.
Leandro Fernández-Pérez   +12 more
doaj   +1 more source

Second to fourth digit ratio (2D:4D) and concentrations of circulating sex hormones in adulthood [PDF]

open access: yes, 2011
BACKGROUND: The second to fourth digit ratio (2D:4D) is used as a marker of prenatal sex hormone exposure. The objective of this study was to examine whether circulating concentrations of sex hormones and SHBG measured in adulthood was associated with 2D:
Bassett, J   +7 more
core   +2 more sources

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao   +2 more
wiley   +1 more source

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