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Tet-on, or Tet-off, that is the question: Advanced conditional gene expression in Aspergillus [PDF]
Fungal Genetics and Biology, 2016 In Aspergillus, controlled gene expression is often achieved using the reverse tetracycline-controlled transactivator (rtTA) dependent Tet-on system, whereby transcription is activated in a titratable manner by addition of the tetracycline derivative ...
Timothy C Cairns +2 more
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Cellular and Molecular Life Sciences, 2017
During the past decade, we have learnt that the most common DNA modification, 5-methylcytosine (5mC), playing crucial roles in development and disease, is not stable but can be actively reversed to its unmodified form via enzymatic catalysis involving the TET enzymes. These ground-breaking discoveries have been achieved thanks to technological advances
Peppi, Koivunen, Tuomas, Laukka
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During the past decade, we have learnt that the most common DNA modification, 5-methylcytosine (5mC), playing crucial roles in development and disease, is not stable but can be actively reversed to its unmodified form via enzymatic catalysis involving the TET enzymes. These ground-breaking discoveries have been achieved thanks to technological advances
Peppi, Koivunen, Tuomas, Laukka
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TET protein inhibitors: Potential and limitations
Biomedicine and Pharmacotherapy, 2023 TET proteins (methylcytosine dioxygenases) play an important role in the regulation of gene expression. Dysregulation of their activity is associated with many serious pathogenic states such as oncological diseases.
Petr Dytrych
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2021
The 5-methylcytosine (5mC) oxidation pathway mediated by TET proteins involves step-wise oxidation of 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). 5fC and 5caC can be removed from DNA by base excision repair and the completion of this pathway results in "demethylation" of 5mC by converting the modified ...
Zhijun, Huang +4 more
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The 5-methylcytosine (5mC) oxidation pathway mediated by TET proteins involves step-wise oxidation of 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). 5fC and 5caC can be removed from DNA by base excision repair and the completion of this pathway results in "demethylation" of 5mC by converting the modified ...
Zhijun, Huang +4 more
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Communications in Numerical Methods in Engineering, 2002
AbstractMotivated by the need for fast robust generation of unstructured grids comprised entirely of hexahedral cells, we approach the issue via an intermediate tetrahedral discretization. This is then followed by subdivision of the tetrahedra into hexahedra and in this note we focus on the geometric construction, properties and limitations of a ‘best ...
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AbstractMotivated by the need for fast robust generation of unstructured grids comprised entirely of hexahedral cells, we approach the issue via an intermediate tetrahedral discretization. This is then followed by subdivision of the tetrahedra into hexahedra and in this note we focus on the geometric construction, properties and limitations of a ‘best ...
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Tet repressor-tet operator interaction
1989Tetracycline resistance genes are widespread among gram-negative aerobic bacteria. A large number of independent isolates have been characterized and most of them shown to belong to five different classes of determinants, named classes A to E. They are usually plasmid- or transposon-encoded and share several genetic and mechanistic features (Chopra et ...
Wolfgang Hillen, Andreas Wissmann
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The American Journal of Emergency Medicine, 2009
Cyanosis is a bluish skin due to deoxygenated hemoglobin or methomoglobin in the arterial blood.Central cyanosis mostly results from cardiovascular or pulmonary shunts. Tet spell is an episodic central cyanosis due to total occlusion of right ventricle outflow in a patient with a congenital heart disease, such as Tetralogy of Fallot (TOF).
Yi-Ming, Weng +3 more
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Cyanosis is a bluish skin due to deoxygenated hemoglobin or methomoglobin in the arterial blood.Central cyanosis mostly results from cardiovascular or pulmonary shunts. Tet spell is an episodic central cyanosis due to total occlusion of right ventricle outflow in a patient with a congenital heart disease, such as Tetralogy of Fallot (TOF).
Yi-Ming, Weng +3 more
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Deception and the tet offensive
Journal of Strategic Studies, 1990(1990). Deception and the tet offensive. Journal of Strategic Studies: Vol. 13, No. 2, pp. 82-98.
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Index on Censorship, 1979
Big Story: How the American Press and Television Reported and Interpreted the Crisis of Tet 1968 in Vietnam and Washington by Peter Braestrup Westview Press, Boulder, Colorado (two volumes) 1,496pp ...
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Big Story: How the American Press and Television Reported and Interpreted the Crisis of Tet 1968 in Vietnam and Washington by Peter Braestrup Westview Press, Boulder, Colorado (two volumes) 1,496pp ...
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