Results 21 to 30 of about 472,621 (287)

Development and application of real-time PCR assays for quantification of genes encoding tetracycline resistance [PDF]

, 2005
We report here the development, validation, and use of three real-time PCR assays to quantify the abundance of the following three groups of tetracycline resistance genes: tet(A) and tet(C); tet(G); and tet genes encoding ribosomal protection proteins ...
Hansen, Glenn, Michel, Frederick C., Morrison, Mark, Wittum, Thomas, Yu, Zhongtang   +4 more
core   +2 more sources

DNA methylation aberrancies as a guide for surveillance and treatment of human cancers

Epigenetics, 2017
DNA methylation aberrancies are hallmarks of human cancers and are characterized by global DNA hypomethylation of repetitive elements and non-CpG rich regions concomitant with locus-specific DNA hypermethylation.
Gangning Liang, Daniel J. Weisenberger
doaj   +1 more source

A novel inhibitor of monooxygenase reversed the activity of tetracyclines against tet(X3)/tet(X4)-positive bacteria

EBioMedicine, 2022
Summary: Background: Tigecycline is one of the few last-resort antibiotics for the treatment of carbapenem-resistant Enterobacteriaceae infection, the incidence of which has been rapidly increasing.
Lei Xu, Yonglin Zhou, Sen Niu, Zhiying Liu, Yinuo Zou, Yanan Yang, Haihua Feng, Dejun Liu, Xiaodi Niu, Xuming Deng, Yang Wang, Jianfeng Wang   +11 more
doaj   +1 more source

3D Printing Provides a Precise Approach in the Treatment of Tetralogy of Fallot, Pulmonary Atresia with Major Aortopulmonary Collateral Arteries. [PDF]

, 2018
Patients with tetralogy of Fallot, pulmonary atresia, and multiple aortopulmonary collateral arteries (Tet PA MAPCAs) have a wide spectrum of anatomy and disease severity.
Anwar, Shafkat, Eghtesady, Pirooz, Raptis, Demetrios A, Rockefeller, Toby, Woodard, Pamela K   +4 more
core   +1 more source

Detection and linkage to mobile genetic elements of tetracycline resistance gene tet(M) in Escherichia coli isolates from pigs [PDF]

, 2014
BACKGROUND: In Escherichia coli the genes involved in the acquisition of tetracycline resistance are mainly tet(A) and tet(B). In addition, tet(M) is the most common tetracycline resistance determinant in enterococci and it is associated with conjugative
Agersø, Yvonne, de la Fuente, Ricardo, de Vries, Lisbeth Elvira, Jurado-Rabadan, Sonia, Orden, Jose A., Ruiz-Santa-Quiteria, Jose A.   +5 more
core   +2 more sources

A nationwide assessment of hepatocellular adenoma resection: Indications and pathological discordance

Hepatology Communications, EarlyView., 2022
Abstract Hepatocellular adenomas (HCAs) are benign liver tumors associated with bleeding or malignant transformation. Data on the indication for surgery are scarce. We analyzed indications and outcome of patients operated for HCAs < 50 mm compared to HCAs ≥ 50 mm. Changes in final postoperative diagnosis were assessed.
Martijn P. D. Haring, Arthur K. E. Elfrink, Christiaan A. J. Oudmaijer, Paul C. M. Andel, Alicia Furumaya, Nenke de Jong, Colin J. J. M. Willems, Thijs Huits, Julie M. L. Sijmons, Eric J. T. Belt, Koop Bosscha, Esther C. J. Consten, Mariëlle M. E. Coolsen, Peter van Duijvendijk, Joris I. Erdmann, Paul Gobardhan, Robbert J. de Haas, Tjarda van Heek, Hwai‐Ding Lam, Wouter K. G. Leclercq, Mike S. L. Liem, Hendrik A. Marsman, Gijs A. Patijn, Türkan Terkivatan, Babs M. Zonderhuis, Izaak Quintus Molenaar, Wouter W. te Riele, Jeroen Hagendoorn, Alexander F. M. Schaapherder, Jan N. M. IJzermans, Carlijn I. Buis, Joost M. Klaase, Koert P. de Jong, Vincent E. de Meijer, the Dutch Benign Liver Tumor Group, R. B. Takkenberg, J. Verheij, O. M. van Delden, J. I. Erdmann, B. V. van Rosmalen, A. Furumaya, G. Kazemier, D. Ramsoekh, J. N. M. IJzermans, R. A. de Man, M. D. Doukas, M. G. Thomeer, A. J. Klompenhouwer, A. F. M. Schaapherder, M. E. Tushuizen, M. J. Coenraad, A. S. L. P. Crobach, M. C. Burgmans, S. Feshtali, M. M. E. Coolsen, M. Kramer, J. C. Beckervordersandforth, I. V. Samarska, C. van der Leij, R. Miclea, J. H. W. de Wilt, P. B. van den Boezem, E. T. T. L. Tjwa, I. Munsterman, S. Vos, S. van Koeverden, V. E. de Meijer, F. J. C. Cuperus, R. J. de Haas, E. W. Duiker, M. P. D. Haring   +70 more
wiley   +1 more source

DNA hypermethylation in disease: mechanisms and clinical relevance

Epigenetics, 2019
Increasing numbers of studies implicate abnormal DNA methylation in cancer and many non-malignant diseases. This is consistent with numerous findings about differentiation-associated changes in DNA methylation at promoters, enhancers, gene bodies, and ...
Melanie Ehrlich
doaj   +1 more source

Various Profiles of tet Genes Addition to tet(X) in Riemerella anatipestifer Isolates From Ducks in China

Frontiers in Microbiology, 2018
To investigate tetracycline resistance and resistant genotype in Riemerella anatipestifer, the tetracycline susceptibility of 212 R. anatipestifer isolates from China between 2011 and 2017 was tested.
De-Kang Zhu, De-Kang Zhu, Hong-Yan Luo, Hong-Yan Luo, Ma-Feng Liu, Ma-Feng Liu, Xin-Xin Zhao, Xin-Xin Zhao, Ren-Yong Jia, Ren-Yong Jia, Shun Chen, Shun Chen, Kun-Feng Sun, Kun-Feng Sun, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Xiao-Yue Chen, Xiao-Yue Chen, An-Chun Cheng, An-Chun Cheng, Ming-Shu Wang, Ming-Shu Wang   +23 more
doaj   +1 more source

Identification of novel tetracycline resistance gene tet(X14) and its co-occurrence with tet(X2) in a tigecycline-resistant and colistin-resistant Empedobacter stercoris

Emerging Microbes and Infections, 2020
Tigecycline is one of the last-resort antibiotics to treat severe infections. Recently, tigecycline resistance has sporadically emerged with an increasing trend, and Tet(X) family represents a new resistance mechanism of tigecycline.
Yingying Cheng, Yong Chen, Yang Liu, Yuqi Guo, Yanzi Zhou, Tingting Xiao, Shuntian Zhang, Hao Xu, Yunbo Chen, Tongling Shan, Yonghong Xiao, Kai Zhou   +11 more
doaj   +1 more source

Characterization of two multidrug-resistant Klebsiella pneumoniae harboring tigecycline-resistant gene tet(X4) in China

Frontiers in Microbiology, 2023
ObjectivesTigecycline is recognized as one of the last-line antibiotics to treat serious bacterial infection caused by carbapenem-resistant Klebsiella pneumoniae (CRKP). The plasmid-borne gene tet(X4) mediates high resistance to tigecycline. However, the
Yanxian Yang, Yanxian Yang, Yanxian Yang, Ruowen He, Ruowen He, Ruowen He, Ruowen He, Yiping Wu, Yiping Wu, Yiping Wu, Mingyang Qin, Mingyang Qin, Jieyun Chen, Jieyun Chen, Jieyun Chen, Yu Feng, Yu Feng, Yu Feng, Runping Zhao, Lei Xu, Xilong Guo, Xilong Guo, Xilong Guo, Guo-Bao Tian, Guo-Bao Tian, Guo-Bao Tian, Min Dai, Bin Yan, Bin Yan, Bin Yan, Li-Na Qin, Li-Na Qin   +31 more
doaj   +1 more source