Results 151 to 160 of about 139,661 (236)

Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review

JEADV Clinical Practice, EarlyView.
ABSTRACT In recent years, innovative topical medications with novel mechanisms of action have emerged to treat common dermatologic conditions such as acne, atopic dermatitis, vitiligo, and actinic keratoses. These molecularly targeted therapies offer improved safety and tolerability compared to traditional options like corticosteroids.
Mary Dyson, Kara Hurley, Hannah Chaudhury, Lara Shehadeh, Cameron West   +4 more
wiley   +1 more source

Surface Chemical Analysis of Plastic Materials by X‐Ray Photoelectron Spectroscopy: Understanding Weathering, Fragmentation and Contaminant Uptake in Marine Environments

Macromolecular Materials and Engineering, EarlyView.
This Perspective demonstrates how X‐ray photoelectron spectroscopy (XPS) uncovers surface chemical changes in plastics, providing insight into weathering‐driven fragmentation and contaminant adsorption. The Perspective underscores XPS's pivotal role in elucidating fragmentation mechanisms, predicting pollutant–plastic interactions, and guiding ...
Tiziano Di Giulio, Cosimino Malitesta, Elisabetta Mazzotta   +2 more
wiley   +1 more source

Mono‐ and Bivalent Poly(iso‐butylene)‐Alanines for Drug‐Delivery of Nimodipine and Triamcinolone Acetonide

Macromolecular Rapid Communications, EarlyView.
Mono‐ and bivalent‐, alanine‐modified poly‐iso‐butylenes, folding into beta‐sheets, were prepared by living carbocationic polymerization and subsequent endgroup modification. These PIB‐conjugates are useful as solid polymers for the drug release of triamcinolone and nimodipine. ABSTRACT Poly‐iso‐butylene (PIB) is a well known biocompatible polymer with
Philipp S. Hilgeroth, Julius F. Butter, Wolfgang H. Binder   +2 more
wiley   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

Comparative Efficiency of ZIF‐67 and ZIF‐67@ZnO Nanocomposites for Trypan Blue Adsorption: Preparation and RSM Modeling

Nano Select, EarlyView.
This study investigates the comparative efficiency of ZIF‐67 and ZIF‐67@ZnO in removing Trypan blue dye from wastewater. The materials exhibit excellent adsorption capacity, stability, and reusability, highlighting their potential as cost‐effective and eco‐friendly adsorbents.
Hassan Aberrwaila, Hajer Chemingui, Amor Hafiane, Madiha Kamoun   +3 more
wiley   +1 more source

Dysregulated proteolytic cascades in Netherton syndrome: from molecular pathology to preclinical drug testing

The Journal of Pathology, EarlyView.
Abstract Netherton syndrome (NS) is a rare, severe, and often life‐threatening disease for which current therapeutic approaches are limited and show variable effectiveness. NS is characterized by excessive epidermal desquamation that results in a highly defective epidermal barrier, constitutive skin inflammation, allergies, and hair abnormalities.
Eleni Zingkou, Evangelos Bisyris, Georgios Pampalakis, Georgia Sotiropoulou   +3 more
wiley   +1 more source

Evidence‐Based and Consensus‐Based Approach to the Treatment of Hidradenitis Suppurativa: Based on the Updated European SK2 Guidelines for the Treatment of Hidradenitis Suppurativa/Acne Inversa

JEADV Clinical Practice, EarlyView.
Wayne P. Gulliver
wiley   +1 more source

An integrated social and natural sciences case study for the reuse of organic wastes as soil amendments

PLANTS, PEOPLE, PLANET, EarlyView.
Reusing organic waste materials, such as animal manure, as soil amendments reduces water and fertiliser demand, contributing to achieving the Sustainable Development Goals. However, organic wastes may contain contaminants of emerging concern (CECs), posing potential ecosystem and human health risks. Despite the importance of this issue, there is a lack
Felicity C. T. Elder, Jose‐Luis Fajardo‐Escoffié, Laura Carter, Emily K. Durant, Katie J. Field, John Nightingale, Brett Sallach, Andrea‐Lorena Garduño‐Jiménez   +7 more
wiley   +1 more source

Contaminants of emerging concern in agricultural soils: Current understanding, overlooked issues, and future priorities

PLANTS, PEOPLE, PLANET, EarlyView.
Contaminants of emerging concern (CECs) in agriculture represent a growing global challenge for food safety and public health. In this review, we synthesized evidence on how substances such as pharmaceuticals, microplastics, and per‐ and polyfluoroalkyl substances (PFAS) enter soils, accumulate in crops, and affect ecological and human health. We found
Laura J. Carter, Evyatar Ben Mordechay, Benny Chefetz, Zeyou Chen, Xinyi Cui, Jay Gan, Hui Li, Audrey Moores, Xiaoyu Gao   +8 more
wiley   +1 more source

Sulfur Vacancy Engineering of Coralloidal Bi2S3@In2S3 Heterojunction for Enhanced Photocatalytic Removal of Cr(VI)/Antibiotic Mixed Pollutants

Rare Metals, EarlyView.
ABSTRACT Defects can tune the band structure of semiconductors, thereby reconfiguring the corresponding heterojunctions. In this study, coralloidal Bi2S3@In2S3 heterostructures rich in sulfur vacancies were successfully developed via a one‐step hydrothermal method with content regulation of the sulfur source.
Lei Zhang, Jianhao Qiu, Biyao Fang, Guanglu Xia, Chen Chen, Meng Liu, Yixin Li, Yiliang Chen, Jianfeng Yao   +8 more
wiley   +1 more source