Results 101 to 110 of about 230,746 (160)

Archaeosomes for Oral Drug Delivery: From Continuous Microfluidics Production to Powdered Formulations

Pharmaceutics
Archaeosomes were manufactured from natural archaeal lipids by a microfluidics-assisted single-step production method utilizing a mixture of di- and tetraether lipids extracted from Sulfolobus acidocaldarius.
Ivan Vidakovic, Karin Kornmueller, Daniela Fiedler, Johannes Khinast, Eleonore Fröhlich, Gerd Leitinger, Christina Horn, Julian Quehenberger, Oliver Spadiut, Ruth Prassl   +9 more
doaj   +1 more source

Membrane lipids of mesophilic anaerobic bacteria thriving in peats have typical archaeal traits

, 2006
The 16S ribosomal DNA based distinction between the bacterial and archaeal domains of life is strongly supported by the membrane lipid composition of the two domains; Bacteria generally contain dialkyl glycerol diester lipids, whereas Archaea produce
Damsté, Jaap S Sinninghe, Hopmans, EC, Hopmans, E.C., Schouten, S, Schouten, S., Sinninghe Damsté, J.S., David, ORP, Coleman, J.M., Weijers, J.W.H., Coleman, JM, Geenevasen, J.A.J., Pancost, R.D., Weijers, JWH, David, O.R.P., Geenevasen, JAJ, Pancost, RD   +15 more
core   +1 more source

Liposomes Containing Tetraether Lipids and Cell‐Penetrating Peptides as Platform Technology for Oral Delivery of Peptides: A Comparative Study on GLP‐1 Analogs

Nano Select
In this study, the potential of liposomes containing tetraether lipids (TELs) and cell‐penetrating peptides (CPPs) as a platform technology for oral delivery of peptides, using the glucagon‐like peptide 1 (GLP‐1) analogs semaglutide, exenatide, and ...
Lorenz Herbster, Giulia Pander, Manuel Ben Böhmann, Tom Eisenzapf, Sabrina Wohlfart, Eric Mühlberg, Walter Mier, Gert Fricker, Philipp Uhl   +8 more
doaj   +1 more source

Glycerol dialkyl glycerol tetraether membrane lipids in lacustrine environments and their application as proxies for palaeoclimate reconstructions. Geologica Ultraiectina (322) [PDF]

, 2010
Lacustrine sediments often contain relatively high amounts of organic matter because of limited bottom water oxygenation and relatively high sedimentation rates.
Freshwater crenarchaeotal membrane lipids as proxy for lake surface temperatures., Sub AW Strat PA OG 3e geldstroom, Blaga, C.I., Organic geochemistry, Sinninghe Damste, Jaap, Reichart, Gert-Jan   +5 more
core  

Folate-conjugated stealth archaeosomes for the targeted delivery of novel antitumoral peptides

, 2016
International audienceIn this work, novel archaeosomes based on Egg-PC and a mixture of PEGylated archaeal tetraether lipids were investigated as nanocarriers for in vitro delivery of an original anticancer peptide.
Jiblaoui, A., Benvegnu, T., Barbeau, J., Glippa, V., Vivès, T., Cormier, P., Cosson, B.   +6 more
core   +1 more source

Air/water interface study of cyclopentane-containing archaeal bipolar lipid analogues.

, 2010
International audienceThe synthesis of novel archaeal lipid analogues is described. The hydrophobic core of these tetraether bipolar lipids were based on a disubstituted 1,3-cyclopentane unit which was further equipped with mannosyl polar head groups ...
Véronique Vié, Julie Barbeau, Alicia Jacquemet, Jacquemet, Alicia, Loïc Lemiègre, Vié, Véronique, Lemiègre, Loïc, Barbeau, Julie, Thierry Benvegnu, Benvegnu, Thierry   +9 more
core   +1 more source

Indices derived from archaeal glycerol dialkyl glycerol tetraether lipids and tetraether-derived sea surface temperature estimates in sediment core MD99-2348 and borehole PRGL1-4

, 2019
Metadata (core/borehole, section, and sample name) and original data (depth, age, and tetraether-based data) generated by Davtian et al. (2019). The age model is based on Sierro et al. (2009) and Frigola et al. (2012). The 1σ analytical uncertainties are
Nina Davtian (7885409), Guillemette Ménot (6975158), Yoann Fagault (7885412), Édouard Bard (6976076)   +3 more
core   +1 more source

Archaeol to tetraether ratio of M. Thermoautotrophicus

, 2018
Archaeol to tetraether ratio of M ...
Könneke, Martin, Evans, Thomas W, Elvert, Marcus, Martin Könneke (6978479), Kai-Uwe Hinrichs (6960101), Heidi Taubner (7578335), Lipp, Julius S, Taubner, Heidi, Julius S Lipp (6977507), Hinrichs, Kai-Uwe, Rishi Ram Adhikari (7578332), Marcus Elvert (6979217), Thomas W Evans (7578329), Adhikari, Rishi Ram   +13 more
core   +1 more source

GDGT cyclization proteins identify the dominant archaeal sources of tetraether lipids in the ocean. [PDF]

Proc Natl Acad Sci U S A, 2019
Zeng Z, Liu XL, Farley KR, Wei JH, Metcalf WW, Summons RE, Welander PV.   +6 more
europepmc   +1 more source

Redox-dependent niche differentiation provides evidence for multiple bacterial sources of glycerol tetraether lipids in lakes. [PDF]

Proc Natl Acad Sci U S A, 2018
Weber Y, Sinninghe Damsté JS, Zopfi J, De Jonge C, Gilli A, Schubert CJ, Lepori F, Lehmann MF, Niemann H.   +8 more
europepmc   +1 more source