Results 121 to 130 of about 1,695 (156)
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Archaeal tetraether bipolar lipids: Structures, functions and applications
Biochimie, 2009Archaea have developed specific tools permitting life under harsh conditions and archaeal lipids are one of these tools. This microreview describes the particular features of tetraether-type archaeal lipids and their potential applications in biotechnology.
Loïc Lemiegre, Thierry Benvegnú
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Stability and proton-permeability of liposomes composed of archaeal tetraether lipids
Biochimica Et Biophysica Acta - Biomembranes, 1994Liposomes composed of tetraether lipids originating from the thermoacidophilic archaeon Sulfolobus acidocaldarius were analyzed for their stability and proton permeability from 20 degrees C up to 80 degrees C. At room temperature, these liposomes are considerably more stable and have a much lower proton permeability than liposomes composed of diester ...
Arnold J M Driessen +2 more
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Archaebacterial bipolar tetraether lipids: Physico-chemical and membrane properties
Chemistry and Physics of Lipids, 2010Bipolar tetraether lipids (BTL) are abundant in archaea and can be chemically synthesized. The structures of BTL are distinctly different from the lipids found in bacteria and eukaryotes. In aqueous solution, BTL can form extraordinarily stable liposomes with different sizes, lamellarities and membrane packing densities.
Parkson Lee-Gau Chong
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Oral peptide delivery by tetraether lipid liposomes
International Journal of Pharmaceutics, 2011The aim of this study is to improve of oral peptide delivery by a novel type of liposomes containing tetraether lipids (TELs) derived from archaea bacteria. Liposomes were used for the oral delivery of the somatostatin analogue octreotide. TELs were extracted from Sulfolobus acidocaldarius and subsequently purified to single compounds.
Johannes, Parmentier +3 more
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Archaeal Tetraether Lipids: Unique Structures and Applications
Applied Biochemistry and Biotechnology, 2002The extremely stable biomolecules manufactured by organisms from extreme environments are of great scientific and engineering interest in the development of robust and stable industrial biocatalysts. Identification of molecules that impart stability under extremes will also have a profound impact on our understanding of cellular survival.
Michael J, Hanford, Tonya L, Peeples
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Biradical Tetraether Lipids from Thermoacidophilic Archaebacteria
1988Archaebacteria are a novel class of micro-organisms, commonly encountered in exceptional ecological niches: methanogens in the absence of oxygen and in the presence of hydrogen and carbon dioxide, halophiles at high salt concentration, thermophiles at high temperature ranging from 60° to 105°. A variety of phylogenetic arguments has led some authors to
A. Gulik +3 more
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Molecular modeling of archaebacterial bipolar tetraether lipid membranes
Chemistry and Physics of Lipids, 2000Membranes composed of glycerol dialkylnonitol tetraether (GDNT) lipids from the thermoacidophilic archaebacterium Sulfolobus acidocaldarius have been studied by molecular modeling. GDNT membranes containing eight cyclopentane rings in the molecule are packed much tighter than those without rings.
J L, Gabriel, P L, Chong
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Purification and characterization of a liposomal-forming tetraether lipid fraction
Biochemical and Biophysical Research Communications, 1990Polar lipid E, PLE, a native tetraether lipid mixture from Sulfolobus acidocaldarius is shown to spontaneously form multilamellar liposomes in aqueous media. PLE lipids were isolated as a single fraction from the crude lipid extract of S. acidocaldarius on a reverse-phase column followed by TLC and methanol precipitation.
S L, Lo, E L, Chang
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Constraints on the Biological Source(s) of the Orphan Branched Tetraether Membrane Lipids
Geomicrobiology Journal, 2009A soil profile from the Saxnäs Mosse peat bog, Sweden, has been analysed for glycerol dialkyl glycerol tetraether (GDGT) membrane lipids and 16S rRNA genes in order to constrain the source of the yet ‘orphan,’ but supposedly bacterial, branched GDGTs. Branched GDGT lipids dominate over archaeal membrane lipids.
Stefan Schouten +2 more
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Total Synthesis of Archaeal 72-Membered Macrocyclic Tetraether Lipids
The Journal of Organic Chemistry, 1998Total synthesis of archaeal 72-membered macrocyclic tetraether lipids 3a and 3b is reported. The synthesis was principally composed of preparation of the functionalized half-sized diether compounds 11 and 15 first followed by appropriate dimerization through Julia coupling and final macrocyclization of the crucial dialdehydes 23 and 31 by McMurry ...
T. Eguchi, K. Ibaragi, K. Kakinuma
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